Emeritus Professor Istvan Toth

Wang, Jingwen, Bashiri, Sahra, Toth, Istvan and Skwarczynski, Mariusz (2024). An analytical protocol for detecting antibody titer levels in serum/saliva by indirect Enzyme-Linked Immunosorbent Assay (ELISA). Peptide antibodies: methods and protocols. (pp. 205-216) edited by Gunnar Houen. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-3914-6_16

Gábos, András and Tóth, István György (2024). A foglalkoztatás és a szegénység alakulásának összefüggései az Európai Unió országaiban és Magyarországon. Társadalmi Riport. (pp. 135-156) TÁRKI Társadalomkutatási Intézet Zrt.. doi: 10.61501/trip.2024.6

Tóth, István György and Csathó, Ábel (2024). Társadalmi konvergencia a kelet-közép-európai országok és referenciaországaik között. Társadalmi Riport. (pp. 45-67) TÁRKI Társadalomkutatási Intézet Zrt.. doi: 10.61501/trip.2024.2

Fan, Jingyi, Toth, Istvan and Stephenson, Rachel J. (2023). Bioconjugated materials in the development of subunit vaccines. Bioconjugated Materials Part 2 Applications in Drug Delivery, Vaccine Formulations and Important Conjugates for Cancer Therapy. (pp. 59-103) edited by Sandeep Kumar Verma and Ashok Kumar Das. Amsterdam, Netherlands: Elsevier. doi: 10.1016/bs.coac.2023.02.005

Faruck, Mohammad Omer, Skwarczynski, Mariusz and Toth, Istvan (2022). Polymer–Peptide Conjugate Vaccine for Oral Immunization. Methods in Molecular Biology. (pp. 35-44) New York, NY: Humana Press Inc.. doi: 10.1007/978-1-0716-1892-9_3

Yang, Jieru, Azuar, Armira, Toth, Istvan and Skwarczynski, Mariusz (2022). Liposomes for the delivery of lipopeptide vaccines. Methods in Molecular Biology. (pp. 295-307) New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-1892-9_15

Zhao, Lili, Bashiri, Sahra, Toth, Istvan and Skwarczynski, Mariusz (2022). Preparation of Trimethyl Chitosan-Based Polyelectrolyte Complexes for Peptide Subunit Vaccine Delivery. Methods in Molecular Biology. (pp. 141-149) New York, NY: Humana Press Inc.. doi: 10.1007/978-1-0716-1900-1_9

Koirala, Prashamsa, Bashiri, Sahra, Toth, Istvan and Skwarczynski, Mariusz (2022). Current Prospects in Peptide-Based Subunit Nanovaccines. Methods in Molecular Biology. (pp. 309-338) New York, NY: Humana Press Inc.. doi: 10.1007/978-1-0716-1892-9_16

Firdaus, Farrhana Ziana, Skwarczynski, Mariusz and Toth, Istvan (2022). Developments in vaccine adjuvants. Vaccine Design: Methods and Protocols, Volume 3: Resources for Vaccine Development. (pp. 145-178) edited by Sunil Thomas. New York, United States: Humana Press. doi: 10.1007/978-1-0716-1892-9_8

Tóth, István György (2022). Kompország lakói 2022-ben: Az USA, az EU, Oroszország és Kína megítélése a magyar közvéleményben. Társadalmi Riport 2022. (pp. 431-453) Budapest, Hungary: TÁRKI Társadalomkutatási Intézet. doi: 10.61501/trip.2022.22

Hussein, Waleed H., Stephenson, Rachel J. and Toth, Istvan (2021). Preface. Peptide conjugation: methods and protocols. (pp. v-v) New York, NY USA: Humana Press.

Hussein, Waleed M. and Toth, Istvan (2021). Peptide-pegylated lipid conjugation via copper-catalyzed alkyne-azide 1,3-dipolar cycloaddition. Peptide conjugation: methods and protocols. (pp. 57-64) New York, NY United States: Humana Press. doi: 10.1007/978-1-0716-1617-8_6

Hussein, Waleed M., Skwarczynski, Mariusz and Toth, Istvan (2021). Double conjugation using mercapto-acryloyl and alkyne-azide reactions for the synthesis of branched multiantigenic vaccine candidates. Peptide conjugation: methods and protocols. (pp. 141-150) New York, NY United States: Humana Press. doi: 10.1007/978-1-0716-1617-8_13

Hussein, Waleed M., Toth, Istvan and Skwarczynski, Mariusz (2021). Peptide-Polymer Conjugation Via Copper-Catalyzed Alkyne-Azide 1,3-Dipolar Cycloaddition. Methods in Molecular Biology. (pp. 1-7) New York, NY United States: Humana Press. doi: 10.1007/978-1-0716-1617-8_1

Madge, Harrison Y.R., Stephenson, Rachel J. and Toth, Istvan (2021). Nanocarrier-based vaccine delivery systems for synthetic peptide vaccines. Handbook of nanotechnology applications: environment, energy, agriculture and medicine. (pp. 509-535) edited by Woei Jye Lau, Kajornsak Faungnawakij, Kuakoon Piyachomkwan and Uracha Rungsardthong Ruktanonchai. Amsterdam, Netherlands: Elsevier. doi: 10.1016/b978-0-12-821506-7.00020-x

Hussein, Waleed M., Skwarczynski, Mariusz and Toth, Istvan (2020). An isodipeptide building block for microwave-assisted solid-phase synthesis of difficult sequence-containing peptides. Peptide synthesis: methods and protocols. (pp. 139-150) edited by Waleed M. Hussein, Mariusz Skwarczynski and Istvan Toth. New York, NY, United States: Springer. doi: 10.1007/978-1-0716-0227-0_9

Hussein, Waleed M., Skwarczynski, Mariusz and Toth, Istvan (2020). Preface. Peptide synthesis: methods and protocols. (pp. v-v) edited by Waleed M. Hussein, Mariusz Skwarczynski and Istvan Toth. New York, NY, United States: Springer.

Tóth, István György and Hudácskó, Szilvia (2020). A koronavírus-járvány társadalmi hatásai a közvélemény-kutatások tükrében. Társadalmi Riport 2020. (pp. 553-572) TÁRKI Társadalomkutatási Intézet Zrt.. doi: 10.61501/trip.2020.25

Medgyesi, Márton and Tóth, István György (2020). Kelet-Közép-Európa legújabb felzárkózási kísérlete: harminc évvel a rendszerváltások után. Társadalmi Riport 2020. (pp. 15-38) TÁRKI Társadalomkutatási Intézet Zrt.. doi: 10.61501/trip.2020.1

Tóth, István György and Szelényi, Iván (2019). The upper middle class: a new aristocracy? Posing the question for post-communist Hungary. Social Report. (pp. 101-119) TÁRKI Társadalomkutatási Intézet Zrt.. doi: 10.61501/trip.2019.6

Nevagi, Reshma J., Toth, Istvan and Skwarczynski, Mariusz (2018). Peptide-based vaccines. Peptide applications in biomedicine, biotechnology and bioengineering. (pp. 327-358) edited by Sotirios Koutsopoulos. Duxford, United Kingdom: Woodhead Publishing (Elsevier). doi: 10.1016/B978-0-08-100736-5.00012-0

Tóth, István György and Szelényi, Iván (2018). Bezáródás és fluiditás a magyar társadalom szerkezetében : Adatolt esszé a felső középosztály bezáródásáról. Társadalmi Riport. (pp. 25-46) TÁRKI Társadalomkutatási Intézet Zrt.. doi: 10.61501/trip.2018.2

Skwarczynski, Mariusz and Toth, Istvan (2017). Micro- and Nanotechnology in Vaccine Development - Introduction. Micro- and Nanotechnology in Vaccine Development . (pp. XVII-XVIII) edited by Skwarczynski, M. and Toth, I.. Kidlington, Oxford, United Kingdom: Elsevier Science.

Marasini, N., Ghaffar, K.A., Skwarczynski, M. and Toth, I. (2017). Liposomes as a vaccine delivery system. Micro and Nanotechnology in Vaccine Development. (pp. 221-239) edited by Mariusz Skwarczynski and Istvan Toth. Kidlington, Oxford, United Kingdom: Elsevier. doi: 10.1016/B978-0-323-39981-4.00012-9

Eskandari, Sharareh, Stephenson, Rachel and Toth, Istvan (2016). Current boundaries in the formulation of lipid based delivery systems. Liposomal delivery systems: advances and challenges. (pp. 160-174) edited by Abdus Samad, Sarwar Beg and Iram Nazish. London, United Kingdom: Future Medicine. doi: 10.4155/9781910419083

Ahmad Fuaad, Abdullah A. H., Skwarczynski, Mariusz and Toth, Istvan (2016). The use of microwave-assisted solid-phase peptide synthesis and click chemistry for the synthesis of vaccine candidates against hookworm infection. Vaccine design: methods and protocols: volume 1: vaccines for human diseases. (pp. 639-653) edited by Thomas, Sunil. New York, NY United States: Springer New York. doi: 10.1007/978-1-4939-3387-7_36

Skwarczynski, Mariusz and Toth, Istvan (2016). Introduction. Micro and nanotechnology in vaccine development: micro and nano technologies. (pp. xvii-xviii) edited by Mariusz Skwarczynski and Istvan Toth. Oxford, United Kingdom: Elsevier. doi: 10.1016/B978-0-323-39981-4.00027-0

Tóth, István György (2016). Középosztály(ok) Magyarországon és Európában. Társadalmi Riport. (pp. 75-97) TÁRKI Társadalomkutatási Intézet Zrt.. doi: 10.61501/trip.2016.4

Skwarczynskim, Mariusz, Zaman, Mehfuz and Toth, Istvan (2013). Lipo-peptides/saccharides in peptide vaccine delivery. Handbook of biologically active peptides. (pp. 571-579) edited by Abba J. Kastin. Amsterdam, Netherlands: Academic Press/Elsevier. doi: 10.1016/B978-0-12-385095-9.00078-6

Skwarczynski, Mariusz and Toth, Istvan (2011). Lipid core peptide system for self-adjuvanting synthetic vaccine delivery. Bioconjugation protocols: Strategies and methods. (pp. 297-308) edited by Sonny S. S. Mark. New York , U.S.A: Humana Press. doi: 10.1007/978-1-61779-151-2_18

Jackson, David C., Chua, Brendon Y., Brown, Lorena E., Moyle, Peter and Toth, Istvan (2010). Lipopeptide-based vaccines. New generation vaccines. (pp. 315-326) edited by Myron M. Levine. New York, U.S.A.; London, U.K.: Informa Healthcare. doi: 10.3109/9781420060744-32

Zaman, Mehfuz, Skwarczynski, Marius and Toth, Istvan (2010). Toll-like receptor 2 mediated dendritic cell activation: Key target for lipopeptide vaccines design. Dendritic Cells: Types, Life Cycles and Biological Functions. (pp. 63-80) edited by Lorraine C. Welles. New York, NY, U.S.A.: Nova Science Publishers.

Simerska, Pavla, Moyle, Peter M., Olive, Colleen and Toth, Istvan (2009). Strategies in oral immunization. Oral Delivery of Macromolecular Drugs: Barriers, Strategies and Future Trends. (pp. 195-222) edited by Bernkop-Schnurch, Andreas. New York, United States: Springer. doi: 10.1007/978-1-4419-0200-9_11

Blanchfield, J. T. and Toth, I. (2005). Modification of peptides and other drugs using lipoamino acids and sugars. Methods in Molecular Biology: Peptide Synthesis and Applications. (pp. 45-61) edited by John Howl. New Jersey: Humana Press. doi: 10.1385/1-59259-877-3:045

Wong, A., Bender, V. and Toth, I. (2003). Drug delivery systems utilizing lipids and sugars. Molecular Pathomechanisms and New Trends in Drug Research. (pp. 599-612) edited by G. Keri and I. Toth. London & New York: Taylor & Francis. doi: 10.1201/9780203219973.ch45

Keri, G. and Toth, I. (2003). Introduction: A breakthrough in modern drug research. Molecular Pathomechanisms and New Trends in Drug Research. (pp. 1-4) edited by G. Keri and I. Toth. London & New York: Taylor & Francis.

Falconer, Robert A. and Toth, Istvan (2002). Lipoamino acid based glycoconjugates for peptide and drug delivery. Peptides for the New Millennium. (pp. 77-78) Dordrecht, The Netherlands: Kluwer Academic Publishers. doi: 10.1007/0-306-46881-6_310

Chan, Yiu-Ngok, Wong, Allan K. and Toth, Istvan (2001). Lipoamino Acid and Liposaccharide Conjugated Peptides: Enhancement of Bioavailability. Peptides: The Wave of the Future. (pp. 955-956) Dordrecht, The Netherlands: Springer Netherlands. doi: 10.1007/978-94-010-0464-0_445

Toth, Istvan, McGeary, Ross, Blanchfield, Joanne, Rhee, Handoo, Alewood, Paul, Adams, David and Good, Michael (2001). Liposaccharides: Utilisation for peptide delivery and for enhancing synthetic peptide immunogenicity. Peptides: The Wave of the Future. (pp. 937-939) edited by Michal Lebl and Richard A. Houghten. Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/978-94-010-0464-0_437

Toth, Istvan, Danton, Malcolm, Reid, Ronald E., Zhong, Guangming, Brunham, Robert, Tóth, Gábor K. and Gibbons, William A. (1993). Lipidic amino acid based synthetic peptide vaccine adjuvant. Peptides 1992. (pp. 823-824) Dordrecht, The Netherlands: Springer Netherlands. doi: 10.1007/978-94-011-1470-7_377

Hussain, Rohanah, Toth, Istvan and Gibbons, William A. (1992). Synthesis of lipidic peptide conjugates of nucleoside antiviral and cytostatic agents. Peptides. (pp. 450-451) Dordrecht, The Netherlands: Springer Netherlands. doi: 10.1007/978-94-011-2264-1_170

del Olmo, Esther, Toth, Istvan, Fonteh, Alfred N. and Gibbons, William A. (1992). Synthesis and biological activity of heteroalkyl lipidic amino acids. Peptides. (pp. 452-453) Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/978-94-011-2264-1_171

Tóth, István György (2025). Mobilitási rezsimek Magyarországon : Az államszocializmus végétől a munkaalapú társadalom időszakáig. socio.hu, 15 (3), 47-65. doi: 10.18030/socio.hu.2025.3.51

Shalash, Ahmed O., Hussein, Waleed M., Nahar, Ummey J., Wang, Jingwen, Lu, Lantian, Azuar, Armira, Kiong, Jolynn J. E., Koirala, Prashamsa, Khalil, Zeinab G. and Toth, Istvan (2025). Rational development of a novel emulgel adjuvant for single‐shot effective vaccination: a multivariate analysis approach. Advanced Materials, 37 (33) 2506496, 1-17. doi: 10.1002/adma.202506496

Akarçeşme, Sümeyra, Cantillon, Bea, Gábos, András, Nolan, Brian and Tóth, István György (2025). Simulating the Impact of Employment Growth on Poverty: Implications for the European Social Targets. Social Inclusion, 13 9903, 13. doi: 10.17645/si.9903

Phumrattanaprapin, Wuttipong, Shalash, Ahmed O., Skwarczynski, Mariusz, Smout, Michael J., Laha, Thewarach, Toth, Istvan and Loukas, Alex (2025). Development of an efficacious oral peptide vaccine against infection with the carcinogenic liver fluke Opisthorchis viverrini. Vaccine, 61 127400, 127400-61. doi: 10.1016/j.vaccine.2025.127400

Shalash, Ahmed O., Wang, Wanyi, Xia, Yihui, Hussein, Waleed M., Bashiri, Sahra, D'Occhio, Michael J., Stephenson, Rachel J., Skwarczynski, Mariusz and Toth, Istvan (2025). Evaluation of novel single-dose vaccine candidates against gonadotropin-releasing hormone (GnRH) in mice. Vaccine, 53 127092, 127092. doi: 10.1016/j.vaccine.2025.127092

Skwarczynski, Mariusz, Alharbi, Nedaa, Nahar, Ummey J., Shalash, Ahmed O., Azuar, Armira, Koirala, Prashamsa, Khisty, Shefali J., Wang, Jingwen, Marasini, Nirmal, Hussein, Waleed M., Khalil, Zeinab G. and Toth, Istvan (2025). Influence of component structural arrangement on cholesterol-antigen conjugate immunogenicity and antisera bactericidal activity against group A Streptococcus. Bioorganic Chemistry, 157 108248, 108248. doi: 10.1016/j.bioorg.2025.108248

Zhao, Guangzu, Sathkumara, Harindra D., Miranda-Hernandez, Socorro, Seifert, Julia, Valencia-Hernandez, Ana Maria, Puri, Munish, Huang, Wenbin, Toth, Istvan, Daly, Norelle, Skwarczynski, Mariusz and Kupz, Andreas (2025). A modular self-assembling and self-adjuvanting multiepitope peptide nanoparticle vaccine platform to improve the efficacy and immunogenicity of BCG. Small, 21 (7) 2406874, 1-16. doi: 10.1002/smll.202406874

Zhang, Jiahui, Madge, Harrison Y. R., Mahmoud, Asmaa, Lu, Lantian, Wang, Wanyi, Huang, Wenbin, Koirala, Prashamsa, Gonzalez Cruz, Jazmina L., Kong, Wei Yang, Bashiri, Sahra, Shalash, Ahmed O., Hussein, Waleed M., Khalil, Zeinab G., Wells, James W., Toth, Istvan and Stephenson, Rachel J. (2025). A synthetic cyclic peptide for promoting antigen presentation and immune activation. NPJ Vaccines, 10 (1) 9, 9-1. doi: 10.1038/s41541-024-01050-4

Nahar, Ummey J., Wang, Jingwen, Shalash, Ahmed O., Lu, Lantian, Islam, Md. T., Alharbi, Nedaa, Koirala, Prashamsa, Khalil, Zeinab G., Capon, Robert J., Hussein, Waleed M., Toth, Istvan and Skwarczynski, Mariusz (2024). Self-assembled monovalent lipidated mannose ligand as a standalone nanoadjuvant. Vaccine, 42 (23) 126060, 126060. doi: 10.1016/j.vaccine.2024.06.027

Fan, Jingyi, Toth, Istvan and Stephenson, Rachel J. (2024). Self-assembling peptides for vaccine adjuvant discovery. Immuno, 4 (4), 325-343. doi: 10.3390/immuno4040021

Huang, Wenbin, Madge, Harrison Y. R., Toth, Istvan and Stephenson, Rachel J. (2024). Cyclic Peptide Conjugate Vaccines and Physically Mixed Cyclic Peptide Vaccines for Subcutaneous Immunization. Methods in Molecular Biology, 2821, 111-127. doi: 10.1007/978-1-0716-3914-6_9

Alharbi, Nedaa, Shalash, Ahmed O., Koirala, Prashamsa, Boer, Jennifer C., Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert J., Plebanski, Magdalena, Toth, Istvan and Skwarczynski, Mariusz (2024). Cholesterol as an inbuilt immunoadjuvant for a lipopeptide vaccine against group A Streptococcus infection. Journal of Colloid and Interface Science, 663, 43-52. doi: 10.1016/j.jcis.2024.02.134

Zhao, Ziyao, Bashiri, Sahra, Ziora, Zyta M., Toth, Istvan and Skwarczynski, Mariusz (2024). COVID-19 variants and vaccine development. Viruses, 16 (5) 757, 757. doi: 10.3390/v16050757

Rivera-Hernandez, Tania, Carnathan, Diane G., Richter, Johanna, Marchant, Patrick, Cork, Amanda J., Elangovan, Gayathiri, Henningham, Anna, Cole, Jason N., Choudhury, Biswa, Moyle, Peter M., Toth, Istvan, Batzloff, Michael R., Good, Michael F., Agarwal, Paresh, Kapoor, Neeraj, Nizet, Victor, Silvestri, Guido and Walker, Mark J. (2024). Efficacy of alum-adjuvanted peptide and carbohydrate conjugate vaccine candidates against Group A Streptococcus pharyngeal infection in a non-human primate model. Vaccines, 12 (4) 382, 1-10. doi: 10.3390/vaccines12040382

Fan, Jingyi, Toth, Istvan and Stephenson, Rachel J. (2024). Recent scientific advancements towards a vaccine against Group A Streptococcus. Vaccines, 12 (3) 272, 1-20. doi: 10.3390/vaccines12030272

Gábos, András, Binder, Barbara, Branyiczki, Réka and Tóth, István György (2024). Unravelling the relationship between employment, social transfers and income poverty: policy and measurement. Journal of European Social Policy, 34 (3), 289-308. doi: 10.1177/09589287241232272

Lu, Lantian, Kong, Wei Yang, Zhang, Jiahui, Firdaus, Farrhana, Wells, James W., Stephenson, Rachel J., Toth, Istvan, Skwarczynski, Mariusz and Cruz, Jazmina L. Gonzalez (2024). Utilizing murine dendritic cell line DC2.4 to evaluate the immunogenicity of subunit vaccines in vitro. Frontiers in Immunology, 15 1298721, 1-13. doi: 10.3389/fimmu.2024.1298721

Koirala, Prashamsa, Shalash, Ahmed O., Chen, Sung-Po R., Faruck, Mohammad O., Wang, Jingwen, Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert J., Monteiro, Michael J., Toth, Istvan and Skwarczynski, Mariusz (2024). Polymeric nanoparticles as oral and intranasal peptide vaccine delivery systems: the role of shape and conjugation. Vaccines, 12 (2) 198, 1-14. doi: 10.3390/vaccines12020198

Madge, Harrison Y. R., Alexander, Suzy, Azuar, Armira, Zhang, Jiahui, Koirala, Prashamsa, Burne, Thomas H., Toth, Istvan and Stephenson, Rachel J. (2023). Synthetic anti-cocaine nanoaccine successfully prevents cocaine-induced hyperlocomotion. Journal of Medicinal Chemistry, 66 (17), 12407-12419. doi: 10.1021/acs.jmedchem.3c00889

Jin, Shengbin, Zhang, Jiahui, Nahar, Ummey J., Huang, Wenbin, Alharbi, Nedaa A., Shalash, Ahmed O., Koirala, Prashamsa, Yang, Jieru, Kiong, Jolynn J. E., Khalil, Zeinab G., Capon, Robert J., Stephenson, Rachel J., Skwarczynski, Mariusz, Toth, Istvan and Hussein, Waleed M. (2023). Activity relationship of poly(ethylenimine)-based liposomes as group A Streptococcus vaccine delivery systems. ACS Infectious Diseases, 9 (8), 1570-1581. doi: 10.1021/acsinfecdis.3c00159

Stephenson, Rachel J. and Toth, Istvan (2023). Anti-cocaine vaccine development: where are we now and where are we going?. Journal of Medicinal Chemistry, 66 (11), 7086-7100. doi: 10.1021/acs.jmedchem.3c00366

Sinclair, Frazer, Begum, Anjuman A., Dai, Charles C., Toth, Istvan and Moyle, Peter M. (2023). Recent advances in the delivery and applications of nonviral CRISPR/Cas9 gene editing. Drug Delivery and Translational Research, 13 (5), 1500-1519. doi: 10.1007/s13346-023-01320-z

Duong, Viet Tram, Skwarczynski, Mariusz and Toth, Istvan (2023). Towards the development of subunit vaccines against tuberculosis: The key role of adjuvant. Tuberculosis, 139 102307, 1-15. doi: 10.1016/j.tube.2023.102307

Duong, Viet Tram, Koirala, Prashamsa, Chen, Sung-Po R., Monteiro, Michael J., Skwarczynski, Mariusz and Toth, Istvan (2023). Multiepitope subunit peptide-based nanovaccine against porcine circovirus type 2 (PCV2) elicited high antibody titers in vaccinated mice. Molecules, 28 (5) 2248, 1-15. doi: 10.3390/molecules28052248

Firdaus, Farrhana Z., Bartlett, Stacey, Hussein, Waleed M., Lu, Lantian, Wright, Quentin, Huang, Wenbin, Nahar, Ummey J., Yang, Jieru, Khongkow, Mattaka, Veitch, Margaret, Koirala, Prashamsa, Ruktanonchai, Uracha R., Monteiro, Michael J., Gonzalez Cruz, Jazmina L., Stephenson, Rachel J., Wells, James W., Toth, Istvan and Skwarczynski, Mariusz (2023). Liposomal formulations of a polyleucine–antigen conjugate as therapeutic vaccines against cervical cancer. Pharmaceutics, 15 (2) 602, 1-15. doi: 10.3390/pharmaceutics15020602

Yang, Jieru, Boer, Jennifer C., Khongkow, Mattaka, Phunpee, Sarunya, Khalil, Zeinab G., Bashiri, Sahra, Deceneux, Cyril, Goodchild, Georgia, Hussein, Waleed M., Capon, Robert J., Ruktanonchai, Uracha, Plebanski, Magdalena, Toth, Istvan and Skwarczynski, Mariusz (2023). The development of surface-modified liposomes as an intranasal delivery system for group A Streptococcus vaccines. Vaccines, 11 (2) 305, 305. doi: 10.3390/vaccines11020305

Szerlauth, Adel, Varga, Árpád, Madácsy, Tamara, Sebők, Dániel, Bashiri, Sahra, Skwarczynski, Mariusz, Toth, Istvan, Maléth, József and Szilagyi, Istvan (2023). Confinement of triple-enzyme-involved antioxidant cascade in two-dimensional nanostructure. ACS Materials Letters, 5 (2), 565-573. doi: 10.1021/acsmaterialslett.2c00580

Koirala, Prashamsa, Chen, Sung‐Po R., Boer, Jennifer C., Khalil, Zeinab G., Deceneux, Cyril, Goodchild, Georgia, Lu, Lantian, Faruck, Mohammad Omer, Shalash, Ahmed O., Bashiri, Sahra, Capon, Robert J., Hussein, Waleed M., Monteiro, Michael J., Plebanski, Magdalena, Toth, Istvan and Skwarczynski, Mariusz (2023). Polymeric nanoparticles as a self‐adjuvanting peptide vaccine delivery system: the role of shape. Advanced Functional Materials, 33 (12) 2209304, 2209304. doi: 10.1002/adfm.202209304

Skwarczynski, Mariusz, Zhao, Guangzu, Ozberk, Victoria, Giddam, Ashwini Kumar, Khalil, Zeinab G., Pandey, Manisha, Hussein, Waleed M., Nevagi, Reshma J., Batzloff, Michael R., Capon, Robert J., Good, Michael F. and Toth, Istvan (2023). Polyphenylalanine as a self-adjuvanting delivery system for peptide-based vaccines: the role of peptide conformation. Australian Journal of Chemistry, 76 (8), 429-436. doi: 10.1071/ch22167

Alharbi, Nedaa, Skwarczynski, Mariusz and Toth, Istvan (2022). The influence of component structural arrangement on peptide vaccine immunogenicity. Biotechnology Advances, 60 108029, 1-24. doi: 10.1016/j.biotechadv.2022.108029

Nahar, Ummey Jannatun, Toth, Istvan and Skwarczynski, Mariusz (2022). Mannose in vaccine delivery. Journal of Controlled Release, 351, 284-300. doi: 10.1016/j.jconrel.2022.09.038

Kiong, Jolynn, Nahar, Ummey Jannatun, Jin, Shengbin, Shalash, Ahmed O., Zhang, Jiahui, Koirala, Prashamsa, Khalil, Zeinab G., Capon, Robert J., Skwarczynski, Mariusz, Toth, Istvan and Hussein, Waleed M. (2022). Development of multilayer nanoparticles for the delivery of peptide-based subunit vaccine against group a Streptococcus. Pharmaceutics, 14 (10) 2151, 1-12. doi: 10.3390/pharmaceutics14102151

Shalash, Ahmed O., Skwarczynski, Mariusz and Toth, Istvan (2022). Perspectives in the vaccine development against Opisthorchis viverrini liver fluke. MedComm – Biomaterials and Applications, 1 (2) e21, 1-8. doi: 10.1002/mba2.21

Azuar, Armira, Madge, Harrison Y. R., Boer, Jennifer C., Gonzalez Cruz, Jazmina L., Wang, Jingwen, Khalil, Zeinab G., Deceneux, Cyril, Goodchild, Georgia, Yang, Jieru, Koirala, Prashamsa, Hussein, Waleed M., Capon, Robert J., Plebanski, Magdalena, Toth, Istvan and Skwarczynski, Mariusz (2022). Poly(hydrophobic amino acids) and liposomes for delivery of vaccine against Group A Streptococcus. Vaccines, 10 (8) 1212, 1-14. doi: 10.3390/vaccines10081212

Fan, Jingyi, Jin, Shengbin, Gilmartin, Lachlan, Toth, Istvan, Hussein, Waleed M. and Stephenson, Rachel J. (2022). Advances in infectious disease vaccine adjuvants. Vaccines, 10 (7) 1120, 1-62. doi: 10.3390/vaccines10071120

Shalash, Ahmed O., Becker, Luke, Yang, Jieru, Giacomin, Paul, Pearson, Mark, Hussein, Waleed M., Loukas, Alex, Toth, Istvan and Skwarczynski, Mariusz (2022). Development of a peptide vaccine against hookworm infection: immunogenicity, efficacy, and immune correlates of protection. Journal of Allergy and Clinical Immunology, 150 (1), 157-169.e10. doi: 10.1016/j.jaci.2022.02.020

Shalash, Ahmed O., Toth, Istvan and Skwarczynski, Mariusz (2022). The potential of developing a protective peptide‐based vaccines against SARS‐CoV‐2. Drug Development Research, 83 (6), 1251-1256. doi: 10.1002/ddr.21969

Shalash, Ahmed O., Azuar, Armira, Madge, Harrison Y. R., Modhiran, Naphak, Amarilla, Alberto A., Liang, Benjamin, Khromykh, Alexander A., Hussein, Waleed M., Chappell, Keith J., Watterson, Daniel, Young, Paul R., Skwarczynski, Mariusz and Toth, Istvan (2022). Peptide-based vaccine against SARS-CoV-2: peptide antigen discovery and screening of adjuvant systems. Pharmaceutics, 14 (4) 856, 856. doi: 10.3390/pharmaceutics14040856

Huang, Wenbin, Madge, Harrison Y. R., Zhang, Jiahui, Gilmartin, Lachlan, Hussein, Waleed M., Khalil, Zeinab G., Koirala, Prashamsa, Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2022). Structure-activity relationship of lipid, cyclic peptide and antigen rearrangement of physically mixed vaccines. International Journal of Pharmaceutics, 617 121614, 1-12. doi: 10.1016/j.ijpharm.2022.121614

Skwarczynski, Mariusz, Bashiri, Sahra, Yuan, Ye, Ziora, Zyta M., Nabil, Osama, Masuda, Keita, Khongkow, Mattaka, Rimsueb, Natchanon, Cabral, Horacio, Ruktanonchai, Uracha, Blaskovich, Mark A. T. and Toth, Istvan (2022). Antimicrobial activity enhancers: towards smart delivery of antimicrobial agents. Antibiotics, 11 (3) 412, 412. doi: 10.3390/antibiotics11030412

Islam, Md. Tanjir, Ho, Mei-Fong, Nahar, Ummey J., Shalash, Ahmed O., Koirala, Prashamsa, Hussein, Waleed M., Stanisic, Danielle I., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2022). Investigation of liposomal self-adjuvanting peptide epitopes derived from conserved blood-stage Plasmodium antigens. PLoS One, 17 (3) e0264961, e0264961. doi: 10.1371/journal.pone.0264961

Mahmoud, Asmaa, Toth, Istvan and Stephenson, Rachel (2022). Developing an effective glycan‐based vaccine for Streptococcus pyogenes. Angewandte Chemie International Edition, 61 (11) e202115342, 1-21. doi: 10.1002/anie.202115342

Zhang, Jiahui, Fan, Jingyi, Skwarczynski, Mariusz, Stephenson, Rachel J, Toth, Istvan and Hussein, Waleed M (2022). Peptide-based nanovaccines in the treatment of cervical cancer: a review of recent advances. International Journal of Nanomedicine, 17, 869-900. doi: 10.2147/ijn.s269986

Madge, Harrison Y. R., Huang, Wenbin, Gilmartin, Lachlan, Rigau-Planella, Berta, Hussein, Waleed M., Khalil, Zeinab G., Koirala, Prashamsa, Santiago, Viviene S., Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2022). Physical mixture of a cyclic lipopeptide vaccine induced high titres of opsonic IgG antibodies against group A streptococcus. Biomaterials Science, 10 (1), 281-293. doi: 10.1039/d1bm01333e

Chowdhury, Silvia, Toth, Istvan and Stephenson, Rachel J. (2022). Dendrimers in vaccine delivery: recent progress and advances. Biomaterials, 280 121303, 121303. doi: 10.1016/j.biomaterials.2021.121303

Marasini, Nirmal, Er, Gerald, Fu, Changkui, Subasic, Christopher N., Ibrahim, Jibriil, Skwarczynski, Mariusz, Toth, Istvan, Whittaker, Andrew K. and Kaminskas, Lisa M. (2022). Development of a hyperbranched polymer-based methotrexate nanomedicine for rheumatoid arthritis. Acta Biomaterialia, 142, 298-307. doi: 10.1016/j.actbio.2022.01.054

Shalash, Ahmed O., Azuar, Armira, Madge, Harrison Y. R., Modhiran, Naphak, Amarilla, Alberto A., Liang, Benjamin, Khromykh, Alexander A., Watterson, Daniel, Young, Paul R., Toth, Istvan and Skwarczynski, Mariusz (2021). Detection and quantification of SARS-CoV-2 receptor binding domain neutralization by a sensitive competitive ELISA assay. Vaccines, 9 (12) 1493, 1-21. doi: 10.3390/vaccines9121493

Shalash, Ahmed O., Hussein, Waleed M., Skwarczynski, Mariusz and Toth, Istvan (2021). Hookworm infection: toward development of safe and effective peptide vaccines. Journal of Allergy and Clinical Immunology, 148 (6), 1394-1419.e6. doi: 10.1016/j.jaci.2021.10.013

Stanisic, Danielle I., Ho, Mei-Fong, Nevagi, Reshma, Cooper, Emily, Walton, Maddison, Islam, Md Tanjir, Hussein, Waleed M., Skwarczynski, Mariusz, Toth, Istvan and Good, Michael F. (2021). Development and evaluation of a cryopreserved whole-parasite vaccine in a rodent model of blood-stage malaria. mBio, 12 (5) e02657-21, e0265721. doi: 10.1128/mBio.02657-21

Bojarska, Joanna, Mieczkowski, Adam, Ziora, Zyta, Skwarczynski, Mariusz, Toth, Istvan, Shalash, Ahmed O., Parang, Keykavous, El-Mowafi, Shaima A., Mohammed, Eman H. M., Elnagdy, Sherif, AlKhazindar, Maha and Wolf, Wojciech M. (2021). Cyclic dipeptides: the biological and structural landscape with special focus on the anti-cancer proline-based scaffold. Biomolecules, 11 (10) 1515, 1515. doi: 10.3390/biom11101515

Shalash, Ahmed O., Becker, Luke, Yang, Jieru, Giacomin, Paul, Pearson, Mark, Hussein, Waleed M., Loukas, Alex, Skwarczynski, Mariusz and Toth, Istvan (2021). Oral peptide vaccine against hookworm infection: correlation of antibody titers with protective efficacy. Vaccines, 9 (9) 1034, 1034. doi: 10.3390/vaccines9091034

Azuar, Armira, Shibu, Mohini A., Adilbish, Nomin, Marasini, Nirmal, Hung, Hong, Yang, Jieru, Luo, Yacheng, Khalil, Zeinab G., Capon, Robert J., Hussein, Waleed M., Toth, Istvan and Skwarczynski, Mariusz (2021). Poly(hydrophobic amino acid) conjugates for the delivery of multiepitope vaccine against Group A Streptococcus. Bioconjugate Chemistry, 32 (11) acs.bioconjchem.1c00333, 2307-2317. doi: 10.1021/acs.bioconjchem.1c00333

Faruck, Mohammad O., Koirala, Prashamsa, Yang, Jieru, D’Occhio, Michael J., Skwarczynski, Mariusz and Toth, Istvan (2021). Polyacrylate-GnRH peptide conjugate as an oral contraceptive vaccine candidate. Pharmaceutics, 13 (7) 1081, 1-15. doi: 10.3390/pharmaceutics13071081

Shalash, Ahmed O., Hussein, Waleed M., Skwarczynski, Mariusz and Toth, Istvan (2021). Key considerations for the development of safe and effective SARS‐CoV‐2 subunit vaccine: a peptide‐based vaccine alternative. Advanced Science, 8 (16) 2100985, 1-35. doi: 10.1002/advs.202100985

Al-Nazal, Hanan A., Cooper, Emily, Ho, Mei Fong, Eskandari, Sharareh, Majam, Victoria, Giddam, Ashwini Kumar, Hussein, Waleed M., Islam, Md Tanjir, Skwarczynski, Mariusz, Toth, Istvan, Kumar, Sanjai, Zaid, Ali, Batzloff, Michael, Stanisic, Danielle I. and Good, Michael F. (2021). Pre-clinical evaluation of a whole-parasite vaccine to control human babesiosis. Cell Host and Microbe, 29 (6), 894-903. doi: 10.1016/j.chom.2021.04.008

Lu, Lantian, Duong, Viet Tram, Shalash, Ahmed O., Skwarczynski, Mariusz and Toth, Istvan (2021). Chemical conjugation strategies for the development of protein-based subunit nanovaccines. Vaccines, 9 (6) 563, 1-24. doi: 10.3390/vaccines9060563

Dai, Charles C., Huang, Wenbin, Yang, Jieru, Hussein, Waleed M., Wang, Jingwen, Khalil, Zeinab G., Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2021). Polyethylenimine quantity and molecular weight influence its adjuvanting properties in liposomal peptide vaccines. Bioorganic and Medicinal Chemistry Letters, 40 127920, 1-7. doi: 10.1016/j.bmcl.2021.127920

Yang, Jieru, Firdaus, Farrhana, Azuar, Armira, Khalil, Zeinab G., Marasini, Nirmal, Capon, Robert J., Hussein, Waleed M., Toth, Istvan and Skwarczynski, Mariusz (2021). Cell-penetrating peptides-based liposomal delivery system enhanced immunogenicity of peptide-based vaccine against group A streptococcus. Vaccines, 9 (5) 499, 499. doi: 10.3390/vaccines9050499

Khatun, Farjana, Dai, Charles C., Rivera-Hernandez, Tania, Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2021). Immunogenicity assessment of cell wall carbohydrates of Group A Streptococcus via self-adjuvanted glyco-lipopeptides. ACS Infectious Diseases, 7 (2) acsinfecdis.0c00722, 390-405. doi: 10.1021/acsinfecdis.0c00722

Azuar, Armira, Li, Zhuoqing, Shibu, Mohini A., Zhao, Lili, Luo, Yacheng, Shalash, Ahmed O., Khalil, Zeinab G., Capon, Robert J., Hussein, Waleed M., Toth, Istvan and Skwarczynski, Mariusz (2021). Poly(hydrophobic amino acid)-based self-adjuvanting nanoparticles for Group A Streptococcus vaccine delivery. Journal of Medicinal Chemistry, 64 (5) acs.jmedchem.0c01660, 2648-2658. doi: 10.1021/acs.jmedchem.0c01660

Apostolopoulos, Vasso, Bojarska, Joanna, Chai, Tsun-Thai, Elnagdy, Sherif, Kaczmarek, Krzysztof, Matsoukas, John, New, Roger, Parang, Keykavous, Lopez, Octavio Paredes, Parhiz, Hamideh, Perera, Conrad O., Pickholz, Monica, Remko, Milan, Saviano, Michele, Skwarczynski, Mariusz, Tang, Yefeng, Wolf, Wojciech M., Yoshiya, Taku, Zabrocki, Janusz, Zielenkiewicz, Piotr, AlKhazindar, Maha, Barriga, Vanessa, Kelaidonis, Konstantinos, Sarasia, Elham Mousavinezhad and Toth, Istvan (2021). A global review on short peptides: frontiers and perspectives. Molecules, 26 (2) 430, 430. doi: 10.3390/molecules26020430

Varamini, Pegah, Dhiman, Kimmi, Khazeni, Sepideh, Mansfeld, Frieda and Toth, Istvan (2021). Lipoamino acid-modified GnRH analogs with receptor-mediated antiproliferative activity in prostate and ovarian cancer cells. Medicinal Chemistry Research, 30 (8), 1577-1587. doi: 10.1007/s00044-021-02755-0

Zhao, Guangzu, Azuar, Armira, Toth, Istvan and Skwarczynski, Mariusz (2021). A potent vaccine delivery system. Bio-protocol, 11 (7) e3973, e3973. doi: 10.21769/bioprotoc.3973

Pandey, Manisha, Ozberk, Victoria, Eskandari, Sharareh, Shalash, Ahmed O., Joyce, Michael A., Saffran, Holly A., Day, Christopher J., Lepletier, Ailin, Spillings, Belinda L., Mills, Jamie-Lee, Calcutt, Ainslie, Fan, Fan, Williams, James T., Stanisic, Danielle I., Hattingh, Laetitia, Gerrard, John, Skwarczynski, Mariusz, Mak, Johnson, Jennings, Michael P., Toth, Istvan, Tyrrell, D. Lorne and Good, Michael F. (2021). Antibodies to neutralising epitopes synergistically block the interaction of the receptor-binding domain of SARS-CoV-2 to ACE 2. Clinical and Translational Immunology, 10 (3) e1260, e1260. doi: 10.1002/cti2.1260

Zhao, Lili, Yang, Jieru, Nahar, Ummey Jannatun, Khalil, Zeinab G., Capon, Robert J., Hussein, Waleed M., Skwarczynski, Mariusz and Toth, Istvan (2020). A dual-adjuvanting strategy for peptide-based subunit vaccines against group A Streptococcus: lipidation and polyelectrolyte complexes. Bioorganic and Medicinal Chemistry, 28 (24) 115823, 115823. doi: 10.1016/j.bmc.2020.115823

Rivera-Hernandez, Tania, Carnathan, Diane G., Jones, Scott, Cork, Amanda J., Davies, Mark R., Moyle, Peter M., Toth, Istvan, Batzloff, Michael R., McCarthy, James, Nizet, Victor, Goldblatt, David, Silvestri, Guido and Walker, Mark J. (2020). Erratum for: An experimental group a Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate model (mBio, (2019) 10, 2, 10.1128/mBio.00693-19). mBio, 11 (6) e02995-20, 1-1. doi: 10.1128/mBio.02995-20

Bashiri, Sahra, Koirala, Prashamsa, Toth, Istvan and Skwarczynski, Mariusz (2020). Carbohydrate immune adjuvants in subunit vaccines. Pharmaceutics, 12 (10) 965, 965-33. doi: 10.3390/pharmaceutics12100965

Dai, Charles C., Yang, Jieru, Hussein, Waleed M., Zhao, Lili, Wang, Xiumin, Khalil, Zeinab G., Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2020). Polyethylenimine: an intranasal adjuvant for liposomal peptide-based subunit vaccine against Group A Streptococcus. ACS Infectious Diseases, 6 (9) acsinfecdis.0c00452, 2502-2512. doi: 10.1021/acsinfecdis.0c00452

Skwarczynski, Mariusz, Chandrudu, Saranya, Rigau-Planella, Berta, Islam, Md. Tanjir, Cheong, Yee S., Liu, Genan, Wang, Xiumin, Toth, Istvan and Hussein, Waleed M. (2020). Progress in the development of subunit vaccines against malaria. Vaccines, 8 (3) 373, 1-19. doi: 10.3390/vaccines8030373

Dai, Chuankai, Khalil, Zeinab G., Hussein, Waleed M., Yang, Jieru, Wang, Xiumin, Zhao, Lili, Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2020). Opsonic activity of conservative versus variable regions of the Group A Streptococcus M protein. Vaccines, 8 (2) 210, 210. doi: 10.3390/vaccines8020210

Madge, Harrison Y. R., Sharma, Hansa, Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert John, Toth, Istvan and Stephenson, Rachel (2020). Structure–activity analysis of cyclic multicomponent lipopeptide self-adjuvanting vaccine candidates presenting Group A Streptococcus antigens. Journal of Medicinal Chemistry, 63 (10) acs.jmedchem.0c00203, 5387-5397. doi: 10.1021/acs.jmedchem.0c00203

Zhao, Lili, Jin, Wanli, Cruz, Jazmina Gonzalez, Marasini, Nirmal, Khalil, Zeinab G., Capon, Robert J., Hussein, Waleed M., Skwarczynski, Mariusz and Toth, Istvan (2020). Development of polyelectrolyte complexes for the delivery of peptide-based subunit vaccines against group A streptococcus. Nanomaterials, 10 (5) 823, 823. doi: 10.3390/nano10050823

Khatun, Farjana, Toth, Istvan and Stephenson, Rachel J. (2020). Immunology of carbohydrate-based vaccines. Advanced Drug Delivery Reviews, 165-166, 117-126. doi: 10.1016/j.addr.2020.04.006

Bartlett, Stacey, Eichenberger, Ramon M., Nevagi, Reshma J., Ghaffar, Khairunnisa Abdul, Marasini, Nirmal, Dai, Yang, Loukas, Alex, Toth, Istvan and Skwarczynski, Mariusz (2020). Lipopeptide-based oral vaccine against hookworm infection. The Journal of Infectious Diseases, 221 (6), 934-942. doi: 10.1093/infdis/jiz528

Skwarczynski, Mariusz and Toth, Istvan (2020). Non-invasive mucosal vaccine delivery: advantages, challenges and the future. Expert Opinion on Drug Delivery, 17 (4), 1-3. doi: 10.1080/17425247.2020.1731468

Bartlett, Stacey, Skwarczynski, Mariusz, Xie, Xin, Toth, Istvan, Loukas, Alex and Eichenberger, Ramon M. (2020). Development of natural and unnatural amino acid delivery systems against hookworm infection. Precision Nanomedicine, 3 (1), 471-482. doi: 10.33218/prnano3(1).191210.1

Skwarczynski, Mariusz, Zhao, Guangzu, Boer, Jennifer C., Ozberk, Victoria, Azuar, Armira, Gonzalez Cruz, Jazmina, Kumar Giddam, Ashwini, Khalil, Zeinab G., Pandey, Manisha, Shibu, Mohini A., Hussein, Waleed M., Nevagi, Reshma J., Batzloff, Michael R., Wells, James W., Capon, Robert J., Plebanski, Magdalena, Good, Michael F. and Toth, Istvan (2020). Poly(amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccines. Science Advances, 6 (5) eaax2285, eaax2285. doi: 10.1126/sciadv.aax2285

Faruck, Mohammad Omer, Zhao, Lili, Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert J., Skwarczynski, Mariusz and Toth, Istvan (2020). Polyacrylate–peptide antigen conjugate as a single-dose oral vaccine against Group A Streptococcus. Vaccines, 8 (1) 23, 1-10. doi: 10.3390/vaccines8010023

Bartlett, Stacey, Skwarczynski, Mariusz and Toth, Istvan (2020). Lipids as activators of innate immunity in peptide vaccine delivery. Current Medicinal Chemistry, 25 (17), 2887-2901. doi: 10.2174/0929867325666181026100849

Dai, Chuankai, Stephenson, Rachel J., Skwarczynski, Mariusz and Toth, Istvan (2020). Application of Fmoc-SPPS, thiol-maleimide conjugation, and copper(I)-catalyzed alkyne-azide cycloaddition "click" reaction in the synthesis of a complex peptide-based vaccine candidate against Group A Streptococcus. Methods in Molecular Biology, 2103, 13-27. doi: 10.1007/978-1-0716-0227-0_2

Ssemaganda, Aloysious, Giddam, Ashwini Kumar, Low, Leanne M., Liu, Xue Q., Ho, Mei-Fong, Zaman, Mehfuz, Hussein, Waleed M., Skwarczynski, Mariusz, Toth, Istvan, Stanisic, Danielle I. and Good, Michael F. (2019). Mannosylated liposomes formulated with whole parasite P. falciparum blood-stage antigens are highly immunogenic in mice. Vaccine, 38 (6), 1494-1504. doi: 10.1016/j.vaccine.2019.11.063

Zhao, Lili, Skwarczynski, Mariusz and Toth, Istvan (2019). Polyelectrolyte-based platforms for the delivery of peptides and proteins. ACS Biomaterials Science & Engineering, 5 (10) acsbiomaterials.9b01135, 4937-4950. doi: 10.1021/acsbiomaterials.9b01135

Skwarczynski, Mariusz and Toth, Istvan (2019). Cell-penetrating peptides in vaccine delivery: facts, challenges and perspectives. Therapeutic Delivery, 10 (8), 465-467. doi: 10.4155/tde-2019-0042

Azuar, Armira, Zhao, Lili, Hei, Tsui Ting, Nevagi, Reshma J., Bartlett, Stacey, Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert J., Toth, Istvan and Skwarczynski, Mariusz (2019). Cholic acid-based delivery system for vaccine candidates against Group A Streptococcus. ACS Medicinal Chemistry Letters, 10 (9) acsmedchemlett.9b00239, 1253-1259. doi: 10.1021/acsmedchemlett.9b00239

Prokai-Tatrai, Katalin, De La Cruz, Daniel L., Nguyen, Vien, Ross, Benjamin P., Toth, Istvan and Prokai, Laszlo (2019). Brain delivery of thyrotropin-releasing hormone via a novel prodrug approach. Pharmaceutics, 11 (7) 349, 349. doi: 10.3390/pharmaceutics11070349

Hussein, Waleed M., Cheong, Yee S., Liu, Chang, Liu, Genan, Begum, Anjuman Ara, Attallah, Maria Adly, Moyle, Peter Michael, Torchilin, Vladimir, Smith, Roger and Toth, Istvan (2019). Peptide-based targeted polymeric nanoparticles for siRNA delivery. Nanotechnology, 30 (41) 415604, 415604. doi: 10.1088/1361-6528/ab313d

Nevagi, Reshma J., Dai, Wei, Khalil, Zeinab G., Hussein, Waleed M., Capon, Robert J., Skwarczynski, Mariusz and Toth, Istvan (2019). Self-assembly of trimethyl chitosan and poly(anionic amino acid)-peptide antigen conjugate to produce a potent self-adjuvanting nanovaccine delivery system. Bioorganic and Medicinal Chemistry, 27 (14), 3082-3088. doi: 10.1016/j.bmc.2019.05.033

Azuar, Armira, Jin, Wanli , Mukaida, Saori, Hussein, Waleed , Toth, Istvan and Skwarczynski, Mariusz (2019). Recent advances in the development of peptide vaccines and their delivery systems against Group A Streptococcus. Vaccines, 7 (3) 58, 58. doi: 10.3390/vaccines7030058

Nevagi, Reshma J., Dai, Wei, Khalil, Zeinab G., Hussein, Waleed M., Capon, Robert J., Skwarczynski, Mariusz and Toth, Istvan (2019). Structure-activity relationship of group A streptococcus lipopeptide vaccine candidates in trimethyl chitosan-based self-adjuvanting delivery system. European Journal of Medicinal Chemistry, 179, 100-108. doi: 10.1016/j.ejmech.2019.06.047

Begum, Anjuman A., Toth, Istvan, Hussein, Waleed M. and Moyle, Peter Michael (2019). Advances in targeted gene delivery. Current Drug Delivery, 16 (7), 588-608. doi: 10.2174/1567201816666190529072914

Begum, Anjuman A., Toth, Istvan and Moyle, Peter M. (2019). Gastrin-releasing peptide receptor-targeted hybrid peptide/phospholipid pDNA/siRNA delivery systems. Nanomedicine, 14 (9), 1153-1171. doi: 10.2217/nnm-2018-0380

Nevagi, Reshma J., Skwarczynski, Mariusz and Toth, Istvan (2019). Polymers for subunit vaccine delivery. European Polymer Journal, 114, 397-410. doi: 10.1016/j.eurpolymj.2019.03.009

Rivera-Hernandez, Tania, Carnathan, Diane G., Jones, Scott, Cork, Amanda J., Davies, Mark R., Moyle, Peter M., Toth, Istvan, Batzloff, Michael R., McCarthy, James, Nizet, Victor, Goldblatt, David, Silvestri, Guido and Walker, Mark J. (2019). An experimental Group A Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate model. mBio, 10 (2) e00693-19. doi: 10.1128/mBio.00693-19

Ssemaganda, Aloysious, Giddam, Ashwini Kumar, Zaman, Mehfuz, Skwarczynski, Mariusz, Toth, Istvan, Stanisic, Danielle I. and Good, Michael F. (2019). Induction of Plasmodium-specific immune responses using liposome-based vaccines. Frontiers in Immunology, 10 135, 135. doi: 10.3389/fimmu.2019.00135

Yang, Jieru, Luo, Yacheng, Shibu, Mohini Anjna, Toth, Istvan and Skwarczynski, Mariusz (2019). Cell-penetrating peptides: efficient vectors for vaccine delivery. Current Drug Delivery, 16 (5), 430-443. doi: 10.2174/1567201816666190123120915

Toth, Istvan and Skwarczynski, Mariusz (2019). Drug delivery Asia. Current Drug Delivery, 16 (7), 586-587. doi: 10.2174/156720181607190917091556

Khongkow, Mattaka, Liu, Tzu-yu, Bartlett, Stacey, Hussein, Waleed M., Nevagi, Reshma, Jia, Zhongfan, Monteiro, Michael J., Wells, James, Ruktanonchai, Uracha Rungsardthong, Skwarczynski, Mariusz and Toth, Istvan (2018). Liposomal formulation of polyacrylate-peptide conjugate as a new vaccine candidate against cervical cancer. Precision Nanomedicine, 1 (3), 183-193. doi: 10.33218/prnano1(3).181003.1

Eskandari, Sharareh, Pattinson, David, Stephenson, Rachel J., Groves, Penny L., Apte, Simon H., Sedaghat, Bita, Chandurudu, Saranya, Doolan, Denise L. and Toth, Istvan (2018). The influence of physicochemical properties of lipopeptide adjuvants on immune response: a rationale for engineering a potent vaccine. Chemistry: A European Journal, 24 (39), 9892-9902. doi: 10.1002/chem.201801378

Begum, Anjuman Ara, Wan, Yu, Toth, Istvan and Moyle, Peter M. (2018). Bombesin/oligoarginine fusion peptides for gastrin releasing peptide receptor (GRPR) targeted gene delivery. Bioorganic and Medicinal Chemistry, 26 (2), 516-526. doi: 10.1016/j.bmc.2017.12.013

Hussein, Waleed M., Choi, Phil M., Zhang, Cheng, Sierecki, Emma, Johnston, Wayne, Jia, Zhongfan, Monteiro, Michael J., Skwarczynski, Mariusz, Gambin, Yann and Toth, Istvan (2018). Investigating the affinity of poly tert-butyl acrylate toward Toll-Like Receptor 2. AIMS Allergy and Immunology, 2 (3), 141-147. doi: 10.3934/allergy.2018.3.141

Nevagi, Reshma J., Khalil, Zeinab G., Hussein, Waleed M., Powell, Jessica, Batzloff, Michael R., Capon, Robert J., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2018). Polyglutamic acid-trimethyl chitosan-based intranasal peptide nano-vaccine induces potent immune responses against group A streptococcus. Acta Biomaterialia, 80, 278-287. doi: 10.1016/j.actbio.2018.09.037

Jaberolansar, Noushin, Chappell, Keith J., Watterson, Daniel, Bermingham, Imogen M., Toth, Istvan, Young, Paul R. and Skwarczynski, Mariusz (2017). Induction of high titred, non-neutralising antibodies by self-adjuvanting peptide epitopes derived from the respiratory syncytial virus fusion protein. Scientific Reports, 7 (1) 11130, 11130. doi: 10.1038/s41598-017-10415-w

Varamini, Pegah, Rafiee, Amirreza, Giddam, Ashwini Kumar, Mansfeld, Friederike M., Steyn, Frederik and Toth, Istvan (2017). Development of new gonadotropin-releasing hormone-modified dendrimer platforms with direct antiproliferative and gonadotropin releasing activity. Journal of Medicinal Chemistry, 60 (20), 8309-8320. doi: 10.1021/acs.jmedchem.6b01771

Schulze, Kai, Ebensen, Thomas, Chandrudu, Saranya, Skwarczynski, Mariusz, Toth, Istvan, Olive, Colleen and Guzman, Carlos A (2017). Bivalent mucosal peptide vaccines administered using the LCP carrier system stimulate protective immune responses against Streptococcus pyogenes infection. Nanomedicine : nanotechnology, biology, and medicine, 13 (8), 2463-2474. doi: 10.1016/j.nano.2017.08.015

Zhao, Guangzu, Chandrudu, Saranya, Skwarczynski, Mariusz and Toth, Istvan (2017). The application of self-assembled nanostructures in peptide-based subunit vaccine development. European Polymer Journal, 93, 670-681. doi: 10.1016/j.eurpolymj.2017.02.014

Marasini, Nirmal, Ghaffar, Khairunnisa Abdul, Giddam, Ashwini Kumar, Batzloff, Michael R., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2017). Highly immunogenic trimethyl chitosan-based delivery system for intranasal lipopeptide vaccines against group A streptococcus. Current Drug Delivery, 14 (5), 701-708. doi: 10.2174/1567201813666160721141322

Wan, Yu, Dai, Wei, Nevagi, Reshma J., Toth, Istvan and Moyle, Peter M. (2017). Multifunctional peptide-lipid nanocomplexes for efficient targeted delivery of DNA and siRNA into breast cancer cells. Acta Biomaterialia, 59, 257-268. doi: 10.1016/j.actbio.2017.06.032

Skwarczynski, Mariusz and Toth, Istvan (2017). Development and delivery of a peptide-based vaccine against group A Streptococcus. Infectious Diseases Hub.

Hussein, Waleed M., Mukaida, Saori, Liu, Tzu-Yu, Toth, Istvan and Skwarczynski, Mariusz (2017). Fluorinated lipids conjugated to peptide antigens do not induce immune responses against cervical cancer. Vaccination Research Open Journal, 1 (1), 39-44. doi: 10.17140/VROJ-1-107

Varamini, Pegah, Mansfeld, Friederike M., Giddam, Ashwini Kumar, Steyn, Frederik and Toth, Istvan (2017). New gonadotropin-releasing hormone glycolipids with direct antiproliferative activity and gonadotropin-releasing potency. International Journal of Pharmaceutics, 521 (1-2), 327-336. doi: 10.1016/j.ijpharm.2017.02.054

Fagan, Vincent, Hussein, Waleed M., Su, Mei, Gidda, Ashwini K., Batzloff, Michael R., Good, Michael F., Toth, Istvan and Simerska, Pavla (2017). Synthesis, characterization and immunological evaluation of self-adjuvanting group a streptococcal vaccine candidates bearing various lipidic adjuvanting moieties. ChemBioChem, 18 (6), 545-553. doi: 10.1002/cbic.201600639

Marasini, Nirmal, Skwarczynski, Mariusz and Toth, Istvan (2017). Intranasal delivery of nanoparticle-based vaccines. Therapeutic Delivery, 8 (3), 151-167. doi: 10.4155/tde-2016-0068

Hussein, Waleed M., Mukaida, Saori, Azmi, Fazren, Bartlett, Stacey, Olivier, Celine, Batzloff, Michael R., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2017). Comparison of fluorinated and nonfluorinated lipids in self-adjuvanting delivery systems for peptide-based vaccines. ACS Medicinal Chemistry Letters, 8 (2), 227-232. doi: 10.1021/acsmedchemlett.6b00453

Marasini, Nirmal, Giddam, Ashwini Kumar, Batzloff, Michael R. , Good, Michael F. , Skwarczynski, Mariusz and Toth, Istvan (2017). Poly-L-lysine-coated nanoparticles are ineffective in inducing mucosal immunity against group a streptococcus. Biochemical Compounds, 5 (1), 1.1-1.6. doi: 10.7243/2052-9341-5-1

Eskandari, Sharareh, Guerin, Thalia, Toth, Istvan and Stephenson, Rachel J. (2017). Recent advances in self-assembled peptides: Implications for targeted drug delivery and vaccine engineering. Advanced Drug Delivery Reviews, 110, 169-187. doi: 10.1016/j.addr.2016.06.013

Hussein, Waleed M., Xu, Jiaxin, Simerska, Pavla and Toth, Istvan (2017). Synthesis of multicomponent peptide-based vaccine candidates against group A streptococcus. Australian Journal of Chemistry, 70 (2), 184-190. doi: 10.1071/CH16501

Ghaffar, Khairunnisa Abdul, Marasini, Nirmal, Giddam, Ashwini Kumar, Batzloff, Michael R., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2017). The role of size in development of mucosal liposome-lipopeptide vaccine candidates against group A streptococcus. Medicinal Chemistry, 13 (1), 22-27. doi: 10.2174/1573406412666160720093138

Khatun, Farjana, Stephenson, Rachel J. and Toth, Istvan (2017). An overview of structural features of antibacterial glycoconjugate vaccines that influence their immunogenicity. Chemistry - A European Journal, 23 (18) chem.201781861, 4233-4254. doi: 10.1002/chem.201603599

Wan, Yu, Moyle, Peter M., Gn, Pei Z. and Toth, Istvan (2017). Design and evaluation of a stearylated multicomponent peptide-siRNA nanocomplex for efficient cellular siRNA delivery.. Nanomedicine, 12 (4), 281-293. doi: 10.2217/nnm-2016-0354

Hussein, Waleed, Choi, Phil, Zhang, Cheng, Su, Mei, Sierecki, Emma, Johnston, Wayne, Fagan, Vincent, Alexandrov, Kirill, Skwarczynski, Mariusz, Gambin, Yann, Toth, Istvan and Simerska, P. (2017). Evaluation of lipopeptides as toll-like receptor 2 ligands. Current Drug Delivery, 14 (7), 935-943. doi: 10.2174/1567201813666160804114107

Toth, Istvan (2017). Polyelectrolyte coated liposome delivery systems against Group A Streptococcus (GAS) infection. Journal of Nanomedicine & Nanotechnology, 08 (04). doi: 10.4172/2157-7439-c1-048

Zaman, Mehfuz, Ozberk, Victoria, Langshaw, Emma L., McPhun, Virginia, Powell, Jessica L., Phillips, Zachary N., Ho, Mei Fong, Calcutt, Ainslie, Batzloff, Michael R., Toth, Istvan, Hill, Geoffrey R., Pandey, Manisha and Good, Michael F. (2016). Novel platform technology for modular mucosal vaccine that protects against streptococcus. Scientific Reports, 6 (1) 39274, 1-11. doi: 10.1038/srep39274

Azmi, Fazren, Skwarczynski, Mariusz and Toth, Istvan (2016). Towards the development of synthetic antibiotics: designs inspired by natural antimicrobial peptides. Current Medicinal Chemistry, 23 (41), 4610-4624. doi: 10.2174/0929867323666160825162435

Marasini, Nirmal, Giddam, Ashwini K., Khalil, Zeinab G., Hussein, Waleed M., Capon, Robert J., Batzloff, Michael R., Good, Michael F., Toth, Istvan and Skwarczynski, Mariusz (2016). Double adjuvanting strategy for peptide-based vaccines: trimethyl chitosan nanoparticles for lipopeptide delivery. Nanomedicine, 11 (24), 3223-3235. doi: 10.2217/nnm-2016-0291

Marasini, Nirmal, Khalil, Zeinab G., Giddam, Ashwini K., Abdul Ghaffar, Khairunnisa, Hussein, Waleed M., Capon, Robert J., Batzloff, Michael R., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2016). Lipid core peptide/poly(lactic-co-glycolic acid) as a highly potent intranasal vaccine delivery system against Group A streptococcus. International Journal of Pharmaceutics, 513 (1-2), 410-420. doi: 10.1016/j.ijpharm.2016.09.057

Begum, Anjuman Ara, Moyle, Peter M. and Toth, Istvan (2016). Investigation of Bombesin peptide as a targeting ligand for the gastrin releasing peptide (GRP) receptor. Bioorganic and Medicinal Chemistry, 24 (22), 5834-5841. doi: 10.1016/j.bmc.2016.09.039

Giddam, Ashwini Kumar, Reiman, Jennifer M., Zaman, Mehfuz, Skwarczynski, Mariusz, Toth, Istvan and Good, Michael F. (2016). A semi-synthetic whole parasite vaccine designed to protect against blood stage malaria. Acta Biomaterialia, 44, 295-303. doi: 10.1016/j.actbio.2016.08.020

Hussein, Waleed M., Liu, Tzu-Yu, Jia, Zhongfan, McMillan, Nigel A. J., Monteiro, Michael J., Toth, Istvan and Skwarczynski, Mariusz (2016). Multiantigenic peptide-polymer conjugates as therapeutic vaccines against cervical cancer. Bioorganic and Medicinal Chemistry, 24 (18), 4372-4380. doi: 10.1016/j.bmc.2016.07.036

Pignatello, Rosario, Simerska, Pavla, Leonardi, Antonio, Abdelrahim, Adel S., Petronio, Giulio Petronio, Fuochi, Virginia, Furneri, Pio Maria, Ruozi, Barbara and Toth, Istvan (2016). Synthesis, characterization and in vitro evaluation of amphiphilic ion pairs of erythromycin and kanamycin antibiotics with liposaccharides. European Journal of Medicinal Chemistry, 120, 329-337. doi: 10.1016/j.ejmech.2016.04.074

Chandrudu, Saranya, Bartlett, Stacey, Khalil, Zeinab G., Jia, Zhongfan, Hussein, Waleed M., Capon, Robert J., Batzloff, Michael R., Good, Michael F., Monteiro, Michael J., Skwarczynski, Mariusz and Toth, Istvan (2016). Linear and branched polyacrylates as a delivery platform for peptide-based vaccines. Therapeutic Delivery, 7 (9), 601-609. doi: 10.4155/tde-2016-0037

Pignatello, Rosario, Musumeci, Teresa, Graziano, Adriana C. E., Lo Furno, Debora, Varamini, Pegah, Mansfeld, Friederike M., Cardile, Venera and Toth, Istvan (2016). A study on liposomal encapsulation of a lipophilic prodrug of LHRH. Pharmaceutical Development and Technology, 21 (6), 664-671. doi: 10.3109/10837450.2015.1041045

Stephenson, Rachel J., Toth, Istvan, Liang, Jiening, Mangat, Amanjot, McManus, Donald P. and You, Hong (2016). Identification of host insulin binding sites on Schistosoma japonicum insulin receptors. PLoS One, 11 (7) e0159704, e0159704. doi: 10.1371/journal.pone.0159704

Kamaruzaman, Khairul A., Moyle, Peter M. and Toth, Istvan (2016). Peptide-based multicomponent oligonucleotide delivery systems: optimisation of poly-l-lysine dendrons for plasmid DNA delivery. International Journal of Peptide Research and Therapeutics, 23 (1), 1-16. doi: 10.1007/s10989-016-9545-5

Rivera-Hernandez, Tania, Pandey, Manisha, Henningham, Anna, Cole, Jason, Choudhury, Biswa, Cork, Amanda J., Gillen, Christine M., Ghaffar, Khairunnisa Abdul, West, Nicholas P., Silvestri, Guido, Good, Michael F., Moyle, Peter M., Toth, Istvan, Nizet, Victor, Batzloff, Michael R. and Walker, Mark J. (2016). Differing efficacies of lead Group A Streptococcal vaccine candidates and full-length M protein in cutaneous and invasive disease models. mBio, 7 (3) e00618-16, e00618-16.1-e00618-16.9. doi: 10.1128/mBio.00618-16

Azmi, Fazren, Elliott, Alysha G., Marasini, Nirmal, Ramu, Soumya, Ziora, Zyta, Kavanagh, Angela M., Blaskovich, Mark A. T., Cooper, Matthew A., Skwarczynski, Mariusz and Toth, Istvan (2016). Short cationic lipopeptides as effective antibacterial agents: design, physicochemical properties and biological evaluation. Bioorganic and Medicinal Chemistry, 24 (10), 2235-2241. doi: 10.1016/j.bmc.2016.03.053

Lee, Wan Ling, Toth, Istvan and Simerska, Pavla (2016). Synthesis of glycolipid-based drug delivery systems for oral administration. Drug Delivery Letters, 6 (1), 38-45. doi: 10.2174/2210303106666160506155139

Marasini, Nirmal, Giddam, Ashwini K., Ghaffar, Khairunnisa A., Batzloff, Michael R., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2016). Multilayer engineered nanoliposomes as a novel tool for oral delivery of lipopeptide-based vaccines against group A Streptococcus. Nanomedicine, 11 (10), 1223-1236. doi: 10.2217/nnm.16.36

Ghaffar, Khairunnisa Abdul, Marasini, Nirmal, Giddam, Ashwini K., Batzloff, Michael, Good, Michael, Skwarczynski, Mariusz and Toth, Istvan (2016). Liposome-based intranasal Delivery of lipopeptide vaccine candidates against Group A Streptococcus. Acta Biomaterialia, 41, 161-168. doi: 10.1016/j.actbio.2016.04.012

Wan, Yu, Moyle, Peter M., Christie, Michelle P. and Toth, Istvan (2016). Nanosized, peptide-based multicomponent DNA delivery systems: optimization of endosome escape activity. Nanomedicine, 11 (8), 907-919. doi: 10.2217/nnm.16.27

Skwarczynski, Mariusz and Toth, Istvan (2016). Peptide-based synthetic vaccines. Chemical Science, 7 (2), 842-854. doi: 10.1039/c5sc03892h

Toth, Istvan (2016). Preface. Current Drug Delivery, 13 (1), 3-3. doi: 10.2174/156720181301160314153150

Moradi, Shayli Varasteh, Hussein, Waleed M., Varamini, Pegah, Simerska, Pavla and Toth, Istvan (2016). Glycosylation, an effective synthetic strategy to improve the bioavailability of therapeutic peptides. Chemical Science, 7 (4), 2492-2500. doi: 10.1039/C5SC04392A

Sedaghat, Bita, Stephenson, Rachel J., Giddam, Ashwini Kumar, Eskandari, Sharareh, Apte, Simon H., Pattinson, David J., Doolan, Denise L. and Toth, Istvan (2016). Synthesis of mannosylated lipopeptides with receptor targeting properties. Bioconjugate Chemistry, 27 (3), 533-548. doi: 10.1021/acs.bioconjchem.5b00547

Hussein, Waleed M., Liu, Tzu-Yu, Maruthayanar, Pirashanthini, Mukaida, Saori, Moyle, Peter M., Wells, James W., Toth, Istvan and Skwarczynski, Mariusz (2016). Double conjugation strategy to incorporate lipid adjuvants into multiantigenic vaccines. Chemical Science, 7 (3), 2308-2321. doi: 10.1039/C5SC03859F

Chandrudu, Saranya, Skwarczynski, Mariusz, Pattinson, David, Apte, Simon H., Doolan, Denise L. and Toth, Istvan (2016). Synthesis and immunological evaluation of peptide-based vaccine candidates against malaria. Biochemical Compounds, 4 (1). doi: 10.7243/2052-9341-4-1

Chan, Amy, Hussein, Waleed M., Ghaffar, Khairunnisa Abdul, Marasini, Nirmal, Mostafa, Ahmed, Eskandari, Sharareh, Batzloff, Michael R., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2016). Structure-activity relationship of lipid core peptide-based Group A Streptococcus vaccine candidates. Bioorganic and Medicinal Chemistry, 24 (14), 3095-3101. doi: 10.1016/j.bmc.2016.03.063

Varamini, Pegah and Toth, Istvan (2016). Recent advances in oral delivery of peptide hormones. Expert Opinion on Drug Delivery, 13 (4), 507-522. doi: 10.1517/17425247.2016.1142526

Apte, Simon H., Stephenson, Rachel J., Simerska, Pavla, Groves, Penny L., Aljohani, Salwa, Eskandari, Sharareh, Toth, Istvan and Doolan, Denise L. (2016). Systematic evaluation of self-adjuvanting lipopeptide nano-vaccine platforms for the induction of potent CD8+ T-cell responses. Nanomedicine, 11 (2), 137-152. doi: 10.2217/nnm.15.184

Simerska, Pavla, Lai, Hoi Ling and Toth, Istvan (2015). Luteinizing hormone releasing hormone/galactose core/lipopeptide. MolBank, 2015 (4) M881, M881. doi: 10.3390/M881

Toth, Istvan (2015). Meet our editorial board member. Mini-Reviews in Medicinal Chemistry, 15 (14), 1131-1131. doi: 10.2174/138955751514151006154835

Tóth, István and Schneider, György (2015). The cytolethal distending toxin-IV cdt coding region in an avian pathogenic Escherichia coli (APEC) strain shows instability and irregular excision pattern. Acta Microbiologica et Immunologica Hungarica, 62 (4), 423-433. doi: 10.1556/030.62.2015.4.7

Moyle, Peter M., Dai, Wei, Liu, Tzu-Yu, Hussein, Waleed M., Maruthayanar, Pirashanthini, Wells, James W., McMillan, Nigel A. J., Skwarczynski, Mariusz and Toth, Istvan (2015). Combined synthetic and recombinant techniques for the development of lipoprotein-based, self-adjuvanting vaccines targeting human papillomavirus type-16 associated tumors. Bioorganic and Medicinal Chemistry Letters, 25 (23), 5570-5575. doi: 10.1016/j.bmcl.2015.10.049

Eskandari, Sharareh, Stephenson, Rachel J., Fuaad, Abdullah Ahmad, Apte, Simon H., Doolan, Denise L. and Toth, Istvan (2015). Synthesis and characterisation of self-assembled and self-adjuvanting asymmetric multi-epitope lipopeptides of ovalbumin. Chemistry - A European Journal, 21 (3), 1251-1261. doi: 10.1002/chem.201404997

Varasteh Moradi, Shayli, Varamini, Pegah, Steyn, Frederik and Toth, Istvan (2015). In vivo pharmacological evaluation of a lactose-conjugated luteinizing hormone releasing hormone analogue. International Journal of Pharmaceutics, 495 (1), 106-111. doi: 10.1016/j.ijpharm.2015.08.095

Jaberolansar, Noushin, Toth, Istvan, Young, Paul R. and Skwarczynski, Mariusz (2015). Recent advances in the development of subunit-based RSV vaccines.. Expert Review of Vaccines, 15 (1), 53-68. doi: 10.1586/14760584.2016.1105134

Cupri, Sarha, Graziano, Adriana C. E., Cardile, Venera, Skwarczynski, Mariusz, Toth, Istvan and Pignatello, Rosario (2015). A study on the encapsulation of an occludin lipophilic derivative in liposomal carriers. Journal of Liposome Research, 25 (4), 287-293. doi: 10.3109/08982104.2014.992025

Chen, Ying-Shan, Green, Colin R., Teague, Rebecca, Perrett, Joshua, Danesh-Meyer, Helen V., Toth, Istvan and Rupenthal, Ilva D. (2015). Intravitreal injection of lipoamino acid-modified connexin43 mimetic peptide enhances neuroprotection after retinal ischemia. Drug Delivery and Translational Research, 5 (5), 480-488. doi: 10.1007/s13346-015-0249-8

Fuaad, Abdullah A. H. Ahmad, Pearson, Mark S., Pickering, Darren A., Becker, Luke, Zhao, Guangzu, Loukas, Alex C., Skwarczynski, Mariusz and Toth, Istvan (2015). Lipopeptide nanoparticles: development of vaccines against hookworm parasite. ChemMedChem, 10 (10), 1647-1654. doi: 10.1002/cmdc.201500227

Fuaad, Abdullah A. H. Ahmad, Pearson, Mark S., Pickering, Darren A., Becker, Luke, Zhao, Guangzu, Loukas, Alex C., Skwarczynski, Mariusz and Toth, Istvan (2015). Back Cover: Lipopeptide Nanoparticles: Development of Vaccines against Hookworm Parasite (ChemMedChem 10/2015). ChemMedChem, 10 (10), 1768-1768. doi: 10.1002/cmdc.201500390

Wan, Yu, Moyle, Peter M and Toth, Istvan (2015). Endosome escape strategies for improving the efficacy of oligonucleotide delivery systems. Current Medicinal Chemistry, 22 (29), 3326-3346. doi: 10.2174/0929867322666150825162941

Toth, Istvan (2015). Meet our editor. Medicinal Chemistry, 11 (5), 415-415. doi: 10.2174/157340641105150630122633

Rosli, Nurlina, Christie, Michelle, Moyle, Peter M. and Toth, Istvan (2015). Peptide based DNA nanocarriers incorporating a cell-penetrating peptide derived from neurturin protein and poly-L-lysine dendrons. Bioorganic & Medicinal Chemistry, 23 (10), 2470-2479. doi: 10.1016/j.bmc.2015.03.058

Moradi, Shayli Varasteh, Varamini, Pegah and Toth, Istvan (2015). Evaluation of the biological properties and the enzymatic stability of glycosylated luteinizing hormone-releasing hormone analogs. AAPS Journal, 17 (5), 1135-1143. doi: 10.1208/s12248-015-9769-x

Chang, Chenghung, Varamini, Pegah, Giddam, Ashwini Kumar, Mansfeld, Friederike M., D'Occhio, Michael J. and Toth, Istvan (2015). Investigation of structure–activity relationships of synthetic anti-gonadotropin releasing hormone vaccine candidates. ChemMedChem, 10 (5), 901-910. doi: 10.1002/cmdc.201500036

Goodwin, Daryn, Varamini, Pegah, Simerska, Pavla, D'Occhio, Michael J. and Toth, Istvan (2015). Design, synthesis and evaluation of a gonadotropin releasing hormone-based subunit vaccine in rams (Ovis aries). Vaccine, 33 (12), 1453-1458. doi: 10.1016/j.vaccine.2015.01.076

Ghaffar, Khairunnisa Abdul, Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert J., Skwarczynski, Mariusz and Toth, Istvan (2015). Levofloxacin and indolicidin for combination antimicrobial therapy. Current Drug Delivery, 12 (1), 108-114. doi: 10.2174/1567201811666140910094050

Ahmad Fuaad, Abdullah A. H., Roubille, Romain, Pearson, Mark S., Pickering, Darren A., Loukas, Alex C., Skwarczynski, Mariusz and Toth, Istvan (2015). The use of a conformational cathepsin D-derived epitope for vaccine development against Schistosoma mansoni. Bioorganic and Medicinal Chemistry, 23 (6), 1307-1312. doi: 10.1016/j.bmc.2015.01.033

Liu, Tzu-Yu, Hussein, Waleed M., Giddam, Ashwini Kumar, Jia, Zhongfan, Reiman, Jennifer M., Zaman, Mehfuz, McMillan, Nigel A. J., Good, Michael F., Monteiro, Michael J., Toth, Istvan and Skwarczynski, Mariusz (2015). Polyacrylate-based delivery system for self-adjuvanting anticancer peptide vaccine. Journal of Medicinal Chemistry, 58 (2), 888-896. doi: 10.1021/jm501514h

Eskandari, Sharareh, Stephenson, Rachel J., Fuaad, Abdullah Ahmad, Apte, Simon H., Doolan, Denise L. and Toth, Istvan (2015). Synthesis and characterisation of self-assembled and self-adjuvanting asymmetric multi-epitope lipopeptides of ovalbumin. Chemistry: A European Journal, 21 (3), 1251-1261. doi: 10.1002/chem.201404997

Liu, Tzu-Yu, Giddam, Ashwini Kumar, Hussein, Waleed M., Jia, Zhongfan, McMillan, Nigel A. J., Monteiro, Michael J., Toth, Istvan and Skwarczynski, Mariusz (2015). Self-adjuvanting therapeutic peptide-based vaccine induce CD8+ cytotoxic T lymphocyte responses in a murine human papillomavirus tumor model. Current Drug Delivery, 12 (1), 3-8. doi: 10.2174/1567201811666141001155729

Azmi, Fazren, Elliott, Alysha G., Khalil, Zeinab G., Hussein, Waleed M., Kavanagh, Angela, Huang, Johnny X., Quezada, Michelle, Blaskovich, Mark A. T., Capon, Robert J., Cooper, Matthew A., Skwarczynski, Mariusz and Toth, Istvan (2015). Self-assembling lipopeptides with a potent activity against Gram-positive bacteria, including multidrug resistant strains. Nanomedicine, 10 (22), 3359-3371. doi: 10.2217/nnm.15.137

Skwarczynski, Mariusz, Boyd, Ben J and Toth, Istvan (2015). Drug delivery Australia. Current Drug Delivery, 12 (1), 2-2. doi: 10.2174/156720181201150310141415

Toth, Istvan (2015). Meet our editorial board member. Current Drug Delivery, 12 (2), 121-121. doi: 10.2174/156720181202150423103624

Sváb, Domonkos, Bálint, Balázs, Maróti, Gergely and Tóth, István (2015). A novel transducible chimeric phage from Escherichia coli O157: H7 Sakai strain encoding Stx1 production. Infection, Genetics and Evolution, 29, 42-47. doi: 10.1016/j.meegid.2014.10.019

Skwarczynski, Mariusz and Toth, Istvan (2014). Recent advances in peptide-based subunit nanovaccines. Nanomedicine, 9 (17), 2657-2669. doi: 10.2217/nnm.14.187

Christie, Michelle P., Toth, Istvan and Simerska, Pavla (2014). Biophysical characterization of lectin-glycan interactions for therapeutics, vaccines and targeted drug-delivery.. Future Medicinal Chemistry, 6 (18), 2113-2129. doi: 10.4155/fmc.14.130

Namjoshi, Sarika, Toth, Istvan, Blanchfield, Joanne T., Trotter, Nicholas, Mancera, Ricardo L. and Benson, Heather A. E. (2014). Enhanced transdermal peptide delivery and stability by lipid conjugation: epidermal permeation, stereoselectivity and mechanistic insights. Pharmaceutical Research, 31 (12), 3304-3312. doi: 10.1007/s11095-014-1420-5

Zaman, Mehfuz, Chandrudu, Saranya, Giddam, Ashwini K., Reiman, Jennifer, Skwarczynski, Mariusz, McPhun, Virginia, Moyle, Peter M., Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2014). Group A Streptococcal vaccine candidate: contribution of epitope to size, antigen presenting cell interaction and immunogenicity. Nanomedicine, 9 (17), 2613-2624. doi: 10.2217/NNM.14.190

Rivera-Hernandez, Tania, Carnathan, Diane G., Moyle, Peter M., Toth, Istvan, West, Nicholas P., Young, Paul L., Silvestri, Guido and Walker, Mark J. (2014). The contribution of non-human primate models to the development of human vaccines. Discovery Medicine, 18 (101), 313-322.

Azmi, Fazren, Ahmad Fuaad, Abdullah Al Hadi, Giddam, Ashwini Kumar, Batzloff, Michael R., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2014). Self-adjuvanting vaccine against group A streptococcus: application of fibrillized peptide and immunostimulatory lipid as adjuvant. Bioorganic and Medicinal Chemistry, 22 (22), 6401-6408. doi: 10.1016/j.bmc.2014.09.042

Goodwin, Daryn, Varamini, Pegah, Simerska, Pavla and Toth, Istvan (2014). Stability, Permeability and Growth-Inhibitory Properties of Gonadotropin-Releasing Hormone Liposaccharides. Pharmaceutical Research, 32 (5), 1570-1584. doi: 10.1007/s11095-014-1558-1

Sedaghat, B., Stephenson, R. and Toth, I. (2014). Targeting the mannose receptor with mannosylated subunit vaccines. Current Medicinal Chemistry, 21 (30), 3405-3418. doi: 10.2174/0929867321666140826115552

Goodwin, Daryn, Simerska, Pavla, Chang, Cheng-Hung, Mansfeld, Friederike M., Varamini, Pegah, D'Occhio, Michael J. and Toth, Istvan (2014). Active immunisation of mice with GnRH lipopeptide vaccine candidates: importance of T helper or multi-dimer GnRH epitope. Bioorganic and Medicinal Chemistry, 22 (17), 4848-4854. doi: 10.1016/j.bmc.2014.06.052

Stephenson, Rachel, You, Hong, McManus, Donald P. and Toth, Istvan (2014). Schistosome vaccine adjuvants in preclinical and clinical research. Vaccines, 2 (3), 654-685. doi: 10.3390/vaccines2030654

Moradi, Shayli Varasteh, Varamini, Pegah and Toth, Istvan (2014). The transport and efflux of glycosylated luteinising hormone-releasing hormone analogues in Caco-2 cell model: contributions of glucose transporters and efflux systems. Journal of Pharmaceutical Sciences, 103 (10), 3217-3224. doi: 10.1002/jps.24120

Marasini, Nirmal, Skwarczynski, Mariusz and Toth, Istvan (2014). Oral delivery of nanoparticle-based vaccines. Expert Review of Vaccines, Early Online (11), 1361-1376. doi: 10.1586/14760584.2014.936852

Stephenson, Rachel, Varamini, Pegah, Butcher, Neville, Minchin, Rodney and Toth, Istvan (2014). Effect of lipidated gonadotropin-releasing hormone peptides on receptor mediated binding and uptake into prostate cancer cells in vitro. Nanomedicine: Nanotechnology, Biology and Medicine, 10 (8), 1799-1808. doi: 10.1016/j.nano.2014.06.015

Fagan, Vincent, Toth, Istvan and Simerska, Pavla (2014). Convergent synthetic methodology for the construction of self-adjuvanting lipopeptide vaccines using a novel carbohydrate scaffold. Beilstein Journal of Organic Chemistry, 10 (1), 1741-1748. doi: 10.3762/bjoc.10.181

Ghaffar, Khairunnisa Abdul, Giddam, Ashwini Kumar, Zaman, Mehfuz, Skwarczynski, Mariusz and Toth, Istvan (2014). Liposomes as Nanovaccine Delivery Systems. Current Topics in Medicinal Chemistry, 14 (9), 1194-1208. doi: 10.2174/1568026614666140329232757

Sarpietro, Maria G., Accolla, Maria L., Santoro, Nancy, Mansfeld, Friederike M., Pignatello, Rosario, Toth, Istvan and Castelli, Francesco (2014). Calorimetry and Langmuir-Blodgett studies on the interaction of a lipophilic prodrug of LHRH with biomembrane models. Journal of Colloid and Interface Science, 421, 122-131. doi: 10.1016/j.jcis.2014.01.040

Anjum, M. F., Jones, E., Morrison, V., Tozzoli, R., Morabito, S., Toth, I., Nagy, B., Smith, G., Aspan, A., Nielsen, E. M., Fach, P., Herrera-León, S., Woodward, M. J. and La Ragione, R. M. (2014). Use of virulence determinants and seropathotypes to distinguish high- and low-risk Escherichia coli O157 and non-O157 isolates from Europe. Epidemiology and Infection, 142 (5), 1019-1028. doi: 10.1017/S0950268813001635

Moyle, Peter M., Dai, Wei, Zhang, Yingkai, Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2014). Site-speciﬁc incorporation of three toll-like receptor 2 targeting adjuvants into semisynthetic, molecularly deﬁned nanoparticles: application to group A streptococcal vaccines. Bioconjugate Chemistry, 25 (5), 965-978. doi: 10.1021/bc500108b

Christie, Michelle P., Simerská, Pavla, Jen, Freda E.-C., Hussein, Waleed M., Rawi, Mohamad F. M., Hartley-Tassell, Lauren E., Day, Christopher J., Jennings, Michael P. and Toth, Istvan (2014). A drug delivery strategy: binding enkephalin to asialoglycoprotein receptor by enzymatic galactosylation. PLoS One, 9 (4) e95024, e95024.1-e95024.10. doi: 10.1371/journal.pone.0095024

Hussein, Waleed M., Liu, Tzu-Yu, Skwarczynski, Mariusz and Toth, Istvan (2014). Toll-like receptor agonists: a patent review (2011 - 2013). Expert Opinion on Therapeutic Patents, 24 (4), 453-470. doi: 10.1517/13543776.2014.880691

Azmi, Fazren, Fuaad, Abdullah Al Hadi Ahmad, Skwarczynski, Mariusz and Toth, Istvan (2014). Recent progress in adjuvant discovery for peptide-based subunit vaccines. Human Vaccines and Immunotherapeutics, 10 (3), 778-796. doi: 10.4161/hv.27332

Cros, Cécile D., Toth, Istvan and Blanchfield, Joanne T. (2014). Delivery of a lactose derivative of endomorphin 1 to the brain via the olfactory epithelial pathway. Bioorganic and Medicinal Chemistry Letters, 24 (5), 1373-1375. doi: 10.1016/j.bmcl.2014.01.041

Toth, Istvan and Skwarczynski, Mariusz (2014). The immune system likes nanotechnology. Nanomedicine, 9 (17), 2607-2609. doi: 10.2217/nnm.14.199

Liu, Tzu-Yu, Fuaad, Abdullah Al-Hadi Ahmad, Toth, Istvan and Skwarczynski, Mariusz (2014). Self-assembled peptide-polymer conjugates as vaccines. Chimica Oggi - Chemistry Today, 32 (2 (Supplement)), 18-22.

Dougall, Annette M., Skwarczynski, Mariusz, Khoshnejad, Makan, Chandrudu, Saranya, Daly, Norelle L., Toth, Istvan and Loukas, Alex (2014). Lipid core peptide targeting the cathepsin D hemoglobinase of Schistosoma mansoni as a component of a schistosomiasis vaccine. Human Vaccines and Immunotherapeutics, 10 (2), 399-409. doi: 10.4161/hv.27057

Simerska, Pavla, Suksamran, Tittaya, Ziora, Zyta Maria, Rivera, Fabian de Labastida, Engwerda, Christian and Toth, Istvan (2014). Ovalbumin lipid core peptide vaccines and their CD4+ and CD8+ T cell responses. Vaccine, 32 (37), 4743-4750. doi: 10.1016/j.vaccine.2014.06.049

Ahmad Fuaad, Abdullah A. H., Jia, Zhongfan, Hartas, Jon, Ziora, Zyta M., Lin, I-Chun, Moyle, Peter M., Batzloff, Michael R., Good, Michael F., Monteiro, Michael J., Skwarczynski, Mariusz and Toth, Istvan (2014). Polymer–peptide hybrids as a highly immunogenic single-dose nanovaccine. Nanomedicine, 9 (1), 35-43. doi: 10.2217/NNM.13.7

Toth, Istvan (2014). Editorial (Thematic issue: nanotechnology for drug delivery applications). Current Drug Delivery, 11 (6), 665-665. doi: 10.2174/156720181106141202112943

Toth, Istvan (2014). Preface. Current Drug Delivery, 11 (1), 1-1. doi: 10.2174/156720181101140212161054

Varamini, Pegah and Toth, Istvan (2013). Lipid- and sugar-modified endomorphins: novel targets for the treatment of neuropathic pain. Frontiers in Pharmacology, 4 (155) Article 155, 1-7. doi: 10.3389/fphar.2013.00155

Eskandari, Sharareh, Varamini, Pegah and Toth, Istvan (2013). Formulation, characterization and permeability study of nano particles of lipo-endomorphin-1 for oral delivery.. Journal of Liposome Research, 23 (4), 311-317. doi: 10.3109/08982104.2013.805339

Ziora, Zyta M., Blaskovich, Mark A., Toth, Istvan and Cooper, Matthew A. (2013). ChemInform abstract: lipoamino acids as major components of absorption promoters in drug delivery. ChemInform, 44 (43), no-no. doi: 10.1002/chin.201343267

Toth, Istvan, Zaman, Mehfuz and Skwarczynski, Mariusz (2013). Feherje alapu vedooltasok nanotechnologiaval. Termézet Világa, 144 (11), 504-508.

Zaman, Mehfuz and Toth, Istvan (2013). Immunostimulation by synthetic lipopeptide-based vaccine candidates: structure-activity relationships. Frontiers in Immunology, 4 (318) Article 318, 1-12. doi: 10.3389/fimmu.2013.00318

Moyle, Peter M., Hartas, Jon, Henningham, Anna, Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2013). An efficient, chemically-defined semisynthetic lipid-adjuvanted nanoparticulate vaccine development system. Nanomedicine: Nanotechnology, Biology and Medicine, 9 (7), 935-944. doi: 10.1016/j.nano.2013.01.009

Simerska, Pavla, Ziora, Zyta Maria, Fagan, Vincent, Goodwin, Daryn, Edrous, Farrah and Toth, Istvan (2013). Design, synthesis and characterisation of mannosylated ovalbumin lipid core peptide self-adjuvanting vaccine delivery system. Drug Delivery and Translational Research, Online First (3), 1-10. doi: 10.1007/s13346-013-0173-8

Simerska, Pavla, Christie, Michelle P., Goodwin, Daryn, Jen, Freda E.-C., Jennings, Michael P. and Toth, Istvan (2013). alpha-1,4-Galactosyltransferase-catalyzed glycosylation of sugar and lipid modified Leu-enkephalins. Journal of Molecular Catalysis B: Enzymatic, In Press, Accepted Manuscript, 1-28. doi: 10.1016/j.molcatb.2013.08.018

Christie, Michelle P., Simerska, Pavla, Jen, Freda E.-C., Jennings, Michael P. and Toth, Istvan (2013). Liposomes for improved enzymatic glycosylation of lipid-modified lactose enkephalin. ChemPlusChem, 78 (8), 793-796. doi: 10.1002/cplu.201300115

Moradi, Shayli Varasteh, Mansfeld, Friederike M. and Toth, Istvan (2013). Synthesis and in vitro evaluation of glycosyl derivatives of luteinizing hormone-releasing hormone (LHRH). Bioorganic and Medicinal Chemistry, 21 (14), 4259-4265. doi: 10.1016/j.bmc.2013.04.068

Liu, Tzu-Yu, Hussein, Waleed M., Jia, Zhongfan, Ziora, Zyta M., McMillan, Nigel A. J., Monteiro, Michael J., Toth, Istvan and Skwarczynski, Mariusz (2013). Self-adjuvanting polymer-peptide conjugates as therapeutic vaccine candidates against cervical cancer. Biomacromolecules, 14 (8), 2798-2806. doi: 10.1021/bm400626w

Skwarczynski, Mariusz, Kowapradit, Jariya, Ziora, Zyta Maria and Toth, Istvan (2013). pH-Triggered peptide self-assembly into fibrils: a potential peptide-based subunit vaccine delivery platform. Biochemical Compounds, 1. doi: 10.7243/2052-9341-1-2

Varamini, Pegah, Blanchfield, Joanne T. and Toth, Istvan (2013). Endomorphin derivatives with improved pharmacological properties. Current Medicinal Chemistry, 20 (22), 2741-2758. doi: 10.2174/0929867311320220002

Chen, Ying-Shan, Toth, Istvan, Danesh-Meyer, Helen V., Green, Colin R. and Rupenthal, Ilva D. (2013). Cytotoxicity and vitreous stability of chemically modified connexin43 mimetic peptides for the treatment of optic neuropathy. Journal of Pharmaceutical Sciences, 102 (7), 2322-2331. doi: 10.1002/jps.23617

Zaman, Mehfuz, Good, Michael F. and Toth, Istvan (2013). Nanovaccines and their mode of action. Methods, 60 (3), 226-231. doi: 10.1016/j.ymeth.2013.04.014

Deng, Zhou J., Liang, Mingtao, Toth, Istvan, Monteiro, Michael and Minchin, Rodney F. (2013). Plasma protein binding of positively and negatively charged polymer-coated gold nanoparticles elicits different biological responses. Nanotoxicology, 7 (3), 314-322. doi: 10.3109/17435390.2012.655342

Chandrudu, Saranya, Simerska, Pavla and Toth, Istvan (2013). Chemical methods for peptide and protein production. Molecules, 18 (4), 4373-4388. doi: 10.3390/molecules18044373

Varamini, Pegah, Goh, Wei Huang, Mansfeld, Friederike M., Blanchfield, Joanne T., Wyse, Bruce D., Smith, Maree T. and Toth, Istvan (2013). Peripherally acting novel lipo-endomorphin-1 peptides in neuropathic pain without producing constipation. Bioorganic & Medicinal Chemistry, 21 (7), 1898-1904. doi: 10.1016/j.bmc.2013.01.044

Rafiee, Amirreza, Mansfeld, Friederike M., Moyle, Peter M. and Toth, Istvan (2013). Synthesis and characterization of luteinizing hormone-releasing hormone (LHRH)-functionalized mini-dendrimers. International Journal of Chemistry, 3 (1), 51-57. doi: 10.4236/ijoc.2013.31006

New, Roger, Bansal, Gurpal S., Bogus, Michael, Zajkowska, Kasia, Rickelt, Steffen and Toth, Istvan (2013). Use of mixed micelles for presentation of building blocks in a new combinatorial discovery methodology: proof-of-concept studies. Molecules, 18 (3), 3427-3441. doi: 10.3390/molecules18033427

Moyle, Peter Michael and Toth, Istvan (2013). Modern subunit vaccines: development, components, and research opportunities. ChemMedChem, 8 (3), 360-376. doi: 10.1002/cmdc.201200487

Zaman, Mehfuz, Chandrudu, Saranya and Toth, Istvan (2013). Strategies for intranasal delivery of vaccines. Drug Delivery and Translational Research, 39 (1), 100-109. doi: 10.1007/s13346-012-0085-z

Toth, Istvan (2013). Preface. Current Drug Delivery, 10 (1), 1-1. doi: 10.2174/1567201811310010001

Skwarczynski, Mariusz, Kamaruzaman, Khairul A., Srinivasan, Saranya, Zaman, Mehfuz, Lin, I-Chun, Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2013). M-protein-derived conformational peptide epitope vaccine candidate against Group A Streptococcus. Current Drug Delivery, 10 (1), 39-45. doi: 10.2174/1567201811310010007

Giddam, Ashwini Kumar, Zaman, Mehfuz, Skwarczynski, Mariusz and Toth, Istvan (2013). Liposome-based delivery system for vaccine candidates: constructing an effective formulation (vol 7, pg 1877, 2012). Nanomedicine, 8 (2), 312-312. doi: 10.2217/nnm.13.0

Hussein, Waleed M., Liu, Tzu-Yu, Toth, Istvan and Skwarczynski, Mariusz (2013). Microwave-assisted synthesis of difficult sequence-containing peptides using the isopeptide method. Organic and Biomolecular Chemistry, 11 (14), 2370-2376. doi: 10.1039/c3ob00030c

Ahmad Fuaad, Abdullah A. H., Azmi, Fazren, Skwarczynski, Mariusz and Toth, Istvan (2013). Peptide conjugation via CuAAC 'click' chemistry. Molecules, 18 (11), 13148-13174. doi: 10.3390/molecules181113148

Giddam, Ashwin Kumar, Zaman, Mehfuz, Skwarczynski, Mariusz and Toth, Istvan (2012). Liposome-based delivery system for vaccine candidates: constructing an effective formulation. Nanomedicine, 7 (12), 1877-1893. doi: 10.2217/nnm.12.157

Lin, I-Chun, Liang, Mingtao, Liu, Tzu-Yu, Jia, Zhongfan, Monteiro, Michael J. and Toth, Istvan (2012). Effect of polymer grafting density on silica nanoparticle toxicity. Bioorganic & Medicinal Chemistry, 20 (23), 6862-6869. doi: 10.1016/j.bmc.2012.09.045

Varamini, Pegah, Hussein, Waleed M., Mansfeld, Friederike M. and Toth, Istvan (2012). Synthesis, biological activity and structure-activity relationship of endomorphin-1/substance P derivatives. Bioorganic & Medicinal Chemistry, 20 (21), 6335-6343. doi: 10.1016/j.bmc.2012.09.003

Skwarczynski, Mariusz, Dougall, Annette M., Khoshnejad, Makan, Chandrudu, Saranya, Pearson, Mark S., Loukas, Alex and Toth, Istvan (2012). Peptide-Based Subunit Vaccine against Hookworm Infection. PLoS One, 7 (10 Article #e46870) e46870, e46870. doi: 10.1371/journal.pone.0046870

Zaman, Mehfuz, Abdel-Aal, Abu-Baker M., Fujita, Yoshio, Ziora, Zyta M., Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2012). Structure-activity relationship for the development of a self-adjuvanting mucosally active lipopeptide vaccine against Streptococcus pyogenes. Journal of Medicinal Chemistry, 55 (19), 8515-8523. doi: 10.1021/jm301074n

Goodwin, D., Simerska, P. and Toth, I. (2012). Peptides as therapeutics with enhanced bioactivity. Current Medicinal Chemistry, 19 (26), 4451-4461. doi: 10.2174/092986712803251548

Mansfeld, Friederike M. and Toth, Istvan (2012). Lipidated analogues of luteinizing hormone-releasing hormone (LHRH) reduce serum levels of follicle-stimulating hormone (FSH) after oral administration. International Journal of Pharmaceutics, 439 (1-2), 216-222. doi: 10.1016/j.ijpharm.2012.09.038

Apte, Simon H., Groves, Penny L., Skwarczynski, Mariusz, Fujita, Yoshio, Chang, Chenghung, Toth, Istvan and Doolan, Denise L. (2012). Vaccination with lipid core peptides fails to induce epitope-specific T cell responses but confers non-specific protective immunity in a malaria model.. PLoS One, 7 (8 Article. No.e40928) e40928, e40928. doi: 10.1371/journal.pone.0040928

Varamini, Pegah, Mansfeld, Friederike M., Blanchfield, Joanne T., Wyse, Bruce D., Smith, Maree T. and Toth, Istvan (2012). Lipo-endomorphin-1 derivatives with systemic activity against neuropathic pain without producing constipation. PLoS One, 7 (8 Article. No.e41909) e41909, e41909. doi: 10.1371/journal.pone.0041909

Abdel-Aal, Abu-Baker M., El-Naggar, Dina, Zaman, Mehfuz, Batzloff, Michael and Toth, Istvan (2012). Design of fully synthetic, self-adjuvanting vaccine incorporating the tumor-associated carbohydrate Tn antigen and lipoamino acid-based toll-like receptor 2 ligand. Journal of Medicinal Chemistry, 55 (15), 6968-6974. doi: 10.1021/jm300822g

Liu, Tzu-Yu, Hussein, Waleed M., Toth, Istvan and Skwarczynski, Mariusz (2012). Advances in peptide-based Human papillomavirus therapeutic vaccines. Current Topics in Medicinal Chemistry, 12 (14), 1581-1592. doi: 10.2174/156802612802652402

Ziora, Zyta M., Blaskovich, Mark A., Toth, Istvan and Cooper, Matthew A. (2012). Lipoamino acids as major components of absorption promoters in drug delivery. Current Topics in Medicinal Chemistry, 12 (14), 1562-1580. doi: 10.2174/156802612802652448

Abdelrahim, Adel S., Simerska, Pavla and Toth, Istvan (2012). Development and characterization of anionic liposaccharides for enhanced oral drug delivery. International Journal of Pharmaceutics, 430 (1-2), 120-128. doi: 10.1016/j.ijpharm.2012.04.018

Varamini, Pegah, Mansfeld, Friederike M., Blanchfield, Joanne T., Wyse, Bruce D., Smith, Maree T. and Toth, Istvan (2012). Synthesis and biological evaluation of an orally active glycosylated endomorphin-1. Journal of Medicinal Chemistry, 55 (12), 5859-5867. doi: 10.1021/jm300418d

Abdelrahim, Adel S., Simerska, Pavla and Toth, Istvan (2012). Liposaccharide-based nanoparticulate drug delivery system. Tetrahedron, 68 (25), 4967-4975. doi: 10.1016/j.tet.2012.04.064

Abdelrahim, Adel S., Simerska, Pavla and Toth, Istvan (2012). Liposaccharides for improved oral delivery of tobramycin. Drug Delivery Letters, 2 (2), 92-97. doi: 10.2174/2210304x11202020092

Ziora, Zyta M., Wimmer, Norbert, New, Roger, Skwarczynski, Mariusz and Toth, Istvan (2012). Lipopeptides for the fragment-based pharmaceutics design. International Journal of Organic Chemistry, 2 (01), 75-81. doi: 10.4236/ijoc.2012.21013

Mansfeld, Friederike M. and Toth, Istvan (2012). Synthesis and plasma stability of disulfide-bridged cyclic endomorphin-1 derivatives. International Journal of Organic Chemistry, 2 (1), 1-6. doi: 10.4236/ijoc.2012.21001

Zaman, Mehfuz, Abdel-Aal, Abu-Baker M., Fujita, Yoshio, Phillipps, Karen S. M., Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2012). Immunological evaluation of lipopeptide group A streptococcus (GAS) vaccine: Structure-activity relationship. PLoS One, 7 (1) e30146, e30146.1-e30146.7. doi: 10.1371/journal.pone.0030146

Lin, I-Chun, Liang, Mingtao, Liu, Tzu-Yu, Monteiro, Michael J. and Toth, Istvan (2012). Cellular transport pathways of polymer coated gold nanoparticles. Nanomedicine, 8 (1), 8-11. doi: 10.1016/j.nano.2011.09.014

Deng, Zhou J., Liang, Mingtao, Toth, Istvan, Monteiro, Michael J. and Minchin, Rodney F. (2012). Molecular interaction of poly(acrylic acid) gold nanoparticles with human fibrinogen. ACS Nano, 6 (10), 8962-8969. doi: 10.1021/nn3029953

Toth, Istvan (2012). Foreword. Current Drug Delivery, 9 (1), i-i. doi: 10.2174/156720112798376023

Skwarczynski, Mariusz, Parhiz, Bibi Hamideh, Soltani, Fatemeh, Srinivasan, Saranya, Kamaruzaman, Khairul A., Lin, I-Chun and Toth, Istvan (2012). Lipid peptide core nanoparticles as multivalent vaccine candidates against Streptococcus pyogenes. Australian Journal of Chemistry, 65 (1), 35-39. doi: 10.1071/CH11292

Bulmer, A. C., Coombes, J. S., Blanchfield, J. T., Toth, I., Fassett, R. G. and Taylor, S. M. (2011). Bile pigment phamacokinetics and absorption in the rat: Therapeutic potential for enteral administration. British Journal of Pharmacology, 164 (7), 1857-1870. doi: 10.1111/j.1476-5381.2011.01413.x

Abdel-Aal, Abu-Baker M., Al-Isae, Kalifa, Zaman, Mehfuz and Toth, Istvan (2011). Simple synthetic toll-like receptor 2 ligands. Bioorganic and Medicinal Chemistry Letters, 21 (19), 5863-5865. doi: 10.1016/j.bmcl.2011.07.102

Ziora, Zyta M., Wimmer, Norbert, New, Roger, Skwarczynski, Mariusz and Toth, Istvan (2011). Synthesis of glycolipopeptidic building blocks for carbohydrate receptor discovery. Carbohydrate Research, 346 (12), 1439-1444. doi: 10.1016/j.carres.2011.03.019

Simerska, Pavla, Moyle, Peter M. and Toth, Istvan (2011). Modern lipid-, carbohydrate-, and peptide-based delivery systems for peptide, vaccine, and gene products. Medicinal Research Reviews, 31 (4), 520-547. doi: 10.1002/med.20191

Skwarczynski, Mariusz and Toth, Istvan (2011). Peptide-based subunit nanovaccines. Current Drug Delivery, 8 (3), 282-289. doi: 10.2174/156720111795256192

Lin, I-Chun, Liang, Mingtao, Liu, Tzu-Yu, Ziora, Zyta M., Monteiro, Michael J. and Toth, Istvan (2011). Interaction of densely polymer-coated gold nanoparticles with epithelial Caco-2 monolayers. Biomacromolecules, 12 (4), 1339-1348. doi: 10.1021/bm200116z

Zaman, Mehfuz, Skwarczynski, Mariusz, Malcolm, Jessica M., Urbani, Carl N., Jia, Zhongfan, Batzloff, Michael R., Good, Michael F., Monteiro, Michael J. and Toth, Istvan (2011). Self-adjuvanting polyacrylic nanoparticulate delivery system for Group A streptococcus (GAS) vaccine. Nanomedicine: Nanotechnology, Biology and Medicine, 7 (2), 168-173. doi: 10.1016/j.nano.2010.10.002

Skwarczynski, Mariusz, Ahmad Fuaad, Abdullah A. H., Rustanti, Lina, Ziora, Zyta M., Aqil, Mohammed, Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2011). Group A streptococcal vaccine candidates based on the conserved conformational epitope from M protein. Drug Delivery Letters, 1 (1), 2-8. doi: 10.2174/2210304X11101010002

Wilke, DV, Jimenez, PC, Araujo, RM, da Silva, WMB, Pessoa, ODL, Silveira, ER, Pessoa, C, de Moraes, MO, Skwarczynski, M, Simerska, P, Toth, I and Costa-Lotufo, LV (2011). Pro-apoptotic activity of lipidic alpha-amino acids isolated from Protopalythoa variabilis (vol 18, pg 7997, 2010). Bioorganic and Medicinal Chemistry, 19 (3), 1366-1366. doi: 10.1016/j.bmc.2010.12.041

Cros, Cecile D., Toth, Istvan and Blanchfield, Joanne T. (2011). Lipophilic derivatives of leu-enkephalinamide: In vitro permeability, stability and in vivo nasal delivery. Bioorganic and Medicinal Chemistry, 19 (4), 1528-1534. doi: 10.1016/j.bmc.2010.12.042

Deng, Zhou J., Liang, Mingtao, Monteiro, Michael, Toth, Istvan and Minchin, Rodney F. (2011). Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation. Nature Nanotechnology, 6 (1), 39-44. doi: 10.1038/NNANO.2010.250

Benson, Heather and Toth, Istvan (2011). The eighth Australian peptide conference: Peptides - Tools, targets and therapeutics. Biopolymers, 96 (2), iii-iii. doi: 10.1002/bip.21610

Abdel-Aal, Abu-Baker M., Zaman, Mehfuz, Fujita, Yoshio, Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2010). Design of three-component vaccines against group A streptococcal infections: Importance of spatial arrangement of vaccine components. Journal of Medical Chemistry, 53 (22), 8041-8046. doi: 10.1021/jm1007787

Wilke, Diego Veras, Jimenez, Paula Christine, Araújo, Renata Mendonça, da Silva, Wildson Max Barbosa, Pessoa, Otília Deusdênia Loiola, Silveira, Edilberto Roch, Pessoa, Claudia, de Moraes, Manoel Odorico, Skwarczynski, Mariusz, Simerska, Paul, Toth, Istvan and Costa-Lotufo, Letícia Veras (2010). Pro-apoptotic activity of lipidic α-amino acids isolated from Protopalythoa variabilis. Bioorganic and Medicinal Chemistry, 18 (22), 7997-8004. doi: 10.1016/j.bmc.2010.09.027

Szécsi, M., Ondré, Dóra, Tóth, I., Magony, S., Wölfling, J., Schneider, Gy and Julesz, J. (2010). Determination of rat 5α-reductase type 1 isozyme activity and its inhibition by novel steroidal oxazolines. Acta Biologica Hungarica, 61 (3), 274-281. doi: 10.1556/ABiol.61.2010.3.4

Skwarczynski, Mariusz, Zaman, Mehfuz, Urbani, Carl N., Lin, I-Chun, Jia, Zhongfan, Batzloff, Michael R., Good, Michael F., Monteiro, Michael J. and Toth, Istvan (2010). Polyacrylate dendrimer nanoparticles: A self-adjuvanting vaccine delivery system. Angewandte Chemie (International Edition), 49 (33), 5742-5745. doi: 10.1002/anie.201002221

Skwarczynski, Mariusz, Zaman, Mehfuz, Urbani, Carl N., Lin, I-Chun, Jia, Zhongfan, Batzloff, Michael R., Good, Michael F., Monteiro, Michael J. and Toth, Istvan (2010). Polyacrylate dendrimer nanoparticles: a self-adjuvanting vaccine delivery system. Angewandte Chemie, 122 (33), 5878-5881. doi: 10.1002/ange.201002221

Coles, DJ, Esposito, A, Chuah, HT and Toth, I (2010). The synthesis and characterization of lipophilic peptide-based carriers for gene delivery. Tetrahedron, 66 (29), 5435-5441. doi: 10.1016/j.tet.2010.05.031

Bergeon, Julie A., Ziora, Zyta M., Abdelrahim, Adel S., Pernevi, Niklas, Moss, Anne R. and Toth, Istvan (2010). In vitro and in vivo evaluation of positively charged liposaccharide derivatives as oral absorption enhancers for the delivery of anionic drugs. Journal of Pharmaceutical Sciences, 99 (5), 2333-2342. doi: 10.1002/jps.21999

Zaman, Mehfuz, Simerska, Pavla and Toth, Istvan (2010). Synthetic polyacrylate polymers as particulate intranasal vaccine delivery systems for the induction of mucosal immune response. Current Drug Delivery, 7 (2), 118-124. doi: 10.2174/156720110791011846

Zaman, M, Abdel-Aal, AM, Phillipps, KSM, Fujita, Y, Good, MF and Toth, I (2010). Structure-activity relationship of lipopeptide Group A streptococcus (GAS) vaccine candidates on toll-like receptor 2. Vaccine, 28 (10), 2243-2248. doi: 10.1016/j.vaccine.2009.12.046

Liang, Mingtao, Lin, I-Chun, Whittaker, Michael R., Minchin, Rodney F., Monteiro, Michael J. and Toth, Istvan (2010). Cellular uptake of densely packed polymer coatings on gold nanoparticles. ACS Nano, 4 (1), 403-413. doi: 10.1021/nn9011237

Skwarczynski, Mariusz, Ziora, Zyta M., Coles, Daniel J., Lin, I-Chun and Toth, Istvan (2010). Thymine, adenine and lipoamino acid based gene delivery systems. Chemical Communications, 46 (18), 3140-3142. doi: 10.1039/b924371b

Zhong, Wei, Skwarczynski, Mariusz and Toth, Istvan (2009). Development of conformational mimetics of conserved Streptococcus pyogenes minimal epitope as vaccine candidates. Current Drug Delivery, 6 (5), 520-527. doi: 10.2174/156720109789941650

Phillipps, Karen S. M., Wykes, Michelle N., Liu, Xue Q., Brown, Melissa, Blanchfield, Joanne T. and Toth, Istvan (2009). A novel synthetic adjuvant enhances dendritic cell function. Immunology, 128 (1), e582-e588. doi: 10.1111/j.1365-2567.2008.03038.x

Abdelrahim, Adel. S., Ziora, Zyta M., Bergeon, Julie A., Moss, Anne R. and Toth, Istvan (2009). Design and synthesis of a series of novel, cationic liposaccharide derivatives as potential penetration enhancers for oral drug delivery. Tetrahedron, 65 (45), 9436-9442. doi: 10.1016/j.tet.2009.08.072

Simerska, Pavla, Moyle, Peter M., Olive, Colleen and Toth, Istvan (2009). Oral vaccine delivery - New strategies and technologies. Current Drug Delivery, 6 (4), 347-358. doi: 10.2174/156720109789000537

Coles, Daniel J. and Toth, Istvan (2009). Dendritic peptide-based carriers for gene delivery. Current Drug Delivery, 6 (4), 338-342. doi: 10.2174/156720109789000465

Toth, Istvan (2009). 2nd Annual Meeting of the Australian Chapter of the Controlled Release Society, Canberra 2009. Current Drug Delivery, 6 (4), 321-321. doi: 10.2174/156720109789000528

Zhong, Wei, Skwarczynski, Mariusz, Simerska, Pavla, Good, Michael F. and Toth, Istvan (2009). Development of highly pure alpha-helical lipoglycopeptides as self-adjuvanting vaccines. Tetrahedron, 65 (17), 3459-3464. doi: 10.1016/j.tet.2009.02.060

Yong, Michelle, Mitchell, Daniel, Caudron, Audrey, Toth, Istvan and Olive, Colleen (2009). Expression of maturation markers on murine dendritic cells in response to group A streptococcal lipopeptide vaccines. Vaccine, 27 (25-26), 3313-3318. doi: 10.1016/j.vaccine.2009.01.087

Simerska, Pavla, Lu, Hao and Toth, Istvan (2009). Synthesis of a Streptococcus pyogenes vaccine candidate based on the M protein PL1 epitope. Bioorganic & Medicinal Chemistry Letters, 19 (3), 821-824. doi: 10.1016/j.bmcl.2008.12.013

Zhong, Wei, Skwarczynski, Mariusz, Fujita, Yoshio, Simerska, Pavla, Good, Michael F. and Toth, Istvan (2009). Design and synthesis of lipopeptide-carbohydrate assembled multivalent vaccine candidates using native chemical ligation. Australian Journal of Chemistry, 62 (9), 993-999. doi: 10.1071/CH09065

Zhong, Wei, Skwarczynski, Mariusz and Toth, Istvan (2009). Lipid core peptide system for gene, drug, and vaccine delivery. Australian Journal of Chemistry, 62 (9), 956-967. doi: 10.1071/CH09149

Yang, Shu, Coles, David J., Esposito, Anna, Mitchell, Deanne J., Toth, Istvan and Minchin, Rodney F. (2009). Cellular uptake of self-assembled cationic peptide-DNA complexes: Multifunctional role of the enhancer chloroquine. Journal of controlled release, 135 (2), 159-165. doi: 10.1016/j.jconrel.2008.12.015

Toth, I., Simerska, P. and Fujita, Y. (2008). Recent advances in design and synthesis of self-adjuvanting lipopeptide vaccines. International Journal of Peptide Research and Therapeutics, 14 (4), 333-340. doi: 10.1007/s10989-008-9147-y

Fujita, Yoshio, Abdel-Aal, Abu-Baker M., Wimmer, Norbert, Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2008). Synthesis and immunological evaluation of self-adjuvanting glycolipopeptide vaccine candidates. Bioorganic & Medicinal Chemistry, 16 (19), 8907-8913. doi: 10.1016/j.bmc.2008.08.064

Ross, Benjamin P., Falconer, Robert A. and Toth,, Istvan (2008). N-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl (N-Dde) Lipoamino Acids. Molbank, 2008: M566 (2), M566. doi: 10.3390/M566

Bulmer, Andrew C., Blanchfield, Joanne T., Toth, Istvan, Fassett, Robert G. and Coombes, Jeff S. (2008). Improved resistance to serum oxidation in Gilbert's syndrome: A mechanism for cardiovascular protection. Atherosclerosis, 199 (2), 390-396. doi: 10.1016/j.atherosclerosis.2007.11.022

Sarpietro, Maria Grazia, Micieli, Dorotea, Pignatello, Rosario, Liang, Ming Tao, Toth, Istvan and Castelli, Francesco (2008). Effect of variation in the chain length and number in modulating the interaction of an immunogenic lipopeptide with biomembrane models. Thermochimica Acta, 471 (1-2), 14-19. doi: 10.1016/j.tca.2008.02.006

Del Borgo, Mark P., Blanchfield, Joanne T. and Toth, Istvan (2008). Internalisation of the mu-opioid receptor by endomorphin-1 and leu-enkephalin is dependant on aromatic amino acid residues. Bioorganic & Medicinal Chemistry, 16 (8), 4341-4346. doi: 10.1016/j.bmc.2008.02.074

Violette, Aude, Faria Cortes, Diego A., Bergeon, Julie A., Falconer, Robert A. and Toth, I. (2008). Optimized LC–MS/MS quantification method for the detection of piperacillin and application to the development of charged liposaccharides as oral penetration enhancers. International Journal of Pharmaceutics, 351 (1-2), 152-157. doi: 10.1016/j.ijpharm.2007.09.039

Liang, M., Toth, I. and Davies, N. M. (2008). A novel method for preparing immune stimulating complexes (ISCOMs) by hydration of freeze-dried lipid matrix. European Journal of Pharmaceutics and Biopharmaceutics, 68 (3), 840-845. doi: 10.1016/j.ejpb.2007.11.017

Simerska, Pavla, Abdel-Aal, Abu-Baker M., Fujita, Yoshio, Moyle, Peter M., McGeary, Ross P., Batzloff, Michael R., Olive, Colleen, Good, Michael F. and Toth, Istvan (2008). Development of a liposaccharide-based delivery system and its application to the design of Group A streptococcal vaccines. Journal of Medicinal Chemistry, 51 (5), 1447-1452. doi: 10.1021/jm701410p

Abdel-Aal, Abu-Baker M., Batzloff, Michael R., Fujita, Yoshio, Barozzi, Nadia, Faria, Andres, Simerska, Pavla, Moyle, Peter M., Good, Michael F. and Toth, Istvan (2008). Structure-activity relationship of a series of synthetic lipopeptide self-adjuvanting group A streptococcal vaccine candidates. Journal of Medicinal Chemistry, 51 (1), 167-172. doi: 10.1021/jm701091d

Koda, Y., Liang, M., Blanchfield, J. T. and Toth, I. (2008). In vitro stability and permeability studies of liposomal delivery systems for a novel lipophilic endomorphin 1 analogue. International Journal of Pharmaceutics, 356 (1-2), 37-43. doi: 10.1016/j.ijpharm.2007.12.036

Koda, Y., Del Borgo, M., Wessling, S., Lazarus, L. H., Okada, Y., Toth, I. and Blanchfield, J. T. (2008). Synthesis and in vitro evaluation of a library of modified endomorphin 1 peptides. Bioorganic & Medicinal Chemistry, 16 (11), 6286-6296. doi: 10.1016/j.bmc.2008.04.020

Liang, M., Davies, N. M. and Toth, I. (2008). Increasing entrapment of peptides within poly(alkyl cyanoacrylate) nanoparticles prepared from water-in-oil microemulsions by copolymerization. International Journal of Pharmaceutics, 362 (1-2), 141-146. doi: 10.1016/j.ijpharm.2008.06.005

Bulmer, A.C., Blanchfield, J.T., Coombes, J.S. and Toth, I. (2008). In vitro permeability and metabolic stability of bile pigments and the effects of hydrophilic and lipophilic modification of biliverdin. Bioorganic & Medicinal Chemistry, 16 (7), 3616-3625. doi: 10.1016/j.bmc.2008.02.008

Bergeon, Julie A., Chan, Yiu-Ngok, Charles, Bruce G. and Toth, Istvan (2008). Oral absorption enhancement of dipeptide L-Glu-L-Trp-OH by lipid and glycosyl conjugation. Peptide Science, 90 (5), 633-643. doi: 10.1002/bip.21003

Moyle, P.M. and Toth, I. (2008). Self-adjuvanting lipopeptide vaccines. Current Medicinal Chemistry, 15 (5), 506-516. doi: 10.2174/092986708783503249

Benson, H. and Toth, I. (2008). Discovery to Drugs: The Peptide Pipeline. Peptide Science, 90 (5), 588.

Benson, Heather and Toth, Istvan (2008). The Fourth International Peptide Symposium: Discovery to drugs: The peptide pipeline. Biopolymers, 90 (5), 588-588. doi: 10.1002/bip.21069

Coles, Daniel J., Yang, Shu, Esposito, Anna, Mitchell, Deanne, Minchin, Rodney F. and Toth, Istvan (2007). The synthesis and characterisation of a novel dendritic system for gene delivery. Tetrahedron, 63 (49), 12207-12214. doi: 10.1016/j.tet.2007.09.048

Olive, C., Moyle, P. and Toth, I. (2007). Towards the Development of a Broadly Protective Group A Streptococcal Vaccine Based on the Lipid-Core Peptide System. Current Medicinal Chemistry, 14 (28), 2976-2988. doi: 10.2174/092986707782794069

Bergeon, JA and Toth, I (2007). Enhancement of oral drug absorption - Effect of lipid conjugation on the enzymatic stability and intestinal permeability of L-GlU-L-Trp-NH2. Bioorganic & Medicinal Chemistry, 15 (22), 7048-7057. doi: 10.1016/j.bmc.2007.07.040

Falconer, RA and Toth, I (2007). Design, synthesis and biological evaluation of novel lipoamino acid-based glycolipids for oral drug delivery. Bioorganic & Medicinal Chemistry, 15 (22), 7012-7020. doi: 10.1016/j.bmc.2007.07.048

Blanchfield, J., Gallagher, O., Cros, C., Lewis, R., Alewood, P. and Toth, I. (2007). Oral absorption and in vivo biodistribution of alpha-conotoxin MII and a lipidic analogue. Biochemical and Biophysical Research Communication, 361 (1), 97-102. doi: 10.1016/j.bbrc.2007.06.138

Moyle, PM, Hari, Y, Huang, N, Olive, C, Good, MF and Toth, I (2007). A technique for the synthesis of highly-pure, mono-epitopic, multi-valent lipid core peptide vaccines. Tetrahedron Letters, 48 (29), 4965-4967. doi: 10.1016/j.tetlet.2007.05.129

Wessling, Susanne T., Ross, Benjamin P., Koda, Yasuko, Blanchfield, Joanne T. and Toth, Istvan (2007). Caco-2 cell permeability and stability of two D-glucopyranuronamide conjugates of thyrotropin-releasing hormone. Bioorganic & Medicinal Chemistry, 15 (14), 4946-4950. doi: 10.1016/j.bmc.2007.04.042

Pignatello, R., Noce, C., Campisi, A., Acquaviva, R., Bucolo, C., Puglisi, G. and Toth, I. (2007). Evaluation of Cell Tolerability of a Series of Lipoamino Acids Using Biological Membranes and a Biomembrane Model.. Current Drug Delivery, 4 (2), 109-121. doi: 10.2174/156720107780362348

Chan, E, Amon, M, Marano, R. J., Wimmer, N, Kearns, P. S., Manolios, N, Rakoczy, P. E. and Toth, I (2007). Novel cationic lipophilic peptides for oligodeoxynucleotide delivery. Bioorganic & Medicinal Chemistry, 15 (12), 4091-4097. doi: 10.1016/j.bmc.2007.03.078

Moyle, Peter M., Olive, Colleen, Ho, Mei-Fong, Pandey, Manisha, Dyer, Joanne, Suhrbier, Andreas, Fujita, Yoshio and Toth, Istvan (2007). Toward the development of prophylactic and therapeutic human papillomavirus type-16 lipopeptide vaccines. Journal of Medicinal Chemistry, 50 (19), 4721-4727. doi: 10.1021/jm070287b

Bulmer, A., Ried, K., Coombes, J., Blanchfield, J., Toth, I. and Wagner, K. (2007). The anti-mutagenic and antioxidant effects of bile pigments in the Ames Salmonella test. Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 629 (2), 122-132. doi: 10.1016/j.mrgentox.2007.01.008

Koda, Y., Shiotani, K., Toth, I., Tsuda, Y., Okada, Y. and Blanchfield, J. (2007). Comparison of the in vitro apparent permeability and stability of opioid mimetic compounds with that of the native peptide. Bioorganic & Medicinal Chemistry Letters, 17 (7), 2043-2046. doi: 10.1016/j.bmcl.2007.01.051

Matthias, A., Blanchfield, J., Penman, K., Bone, K., Toth, I. and Lehmann, R. (2007). Permeability studies of Kavalactones using a Caco-2 cell monolayer model. Journal of Clinical Pharmacy and Therapeutics, 32 (3), 233-239. doi: 10.1111/j.1365-2710.2007.00810.x

Toth, I. (2007). A védőoltások gyógyszerkémiájának egyik legújabb fejezete. Zsír-aminosav komplexen alapuló vakcinák (Recent developments in prophylactic drug chemistry. Vaccines based on fatty-amino acid complexes). Magyar kémikusok lapja, 62, 274-276.

Khoshnejad, M., Young, P. R., Toth, I. and Minchin, R. F. (2007). Modified Influenza Virosomes: Recent Advances and Potential in Gene Delivery. Current Medicinal Chemistry, 14 (29), 3152-3156. doi: 10.2174/092986707782793989

Kim, I., Nishi, I., Tsai, H., Bradford, T., Koda, Y., Watanabe, T., Morriseau, C., Blanchfield, J., Toth, I. and Hammock, B. (2007). Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase. Bioorganic & Medicinal Chemistry, 15 (1), 312-323. doi: 10.1016/j.bmc.2006.09.057

Olive, C., Schulze, K., Sun, H. K., Ebensen, T., Horváth, A., Toth, I. and Guzman, C. A. (2007). Enhanced protection against Streptococcus pyogenes infection by intranasal vaccination with a dual antigen component M protein/SfbI lipid core peptide vaccine formulation. Vaccine, 25 (10), 1789-1797. doi: 10.1016/j.vaccine.2006.11.031

Moyle, P. M., Olive, C., Ho, M. F., Burgess, M., Karpati, L., Good, M. F. and Toth, I. (2006). Method for the Synthesis of Multi-Epitopic Streptococcus pyogenes Lipopeptide Vaccines Using Native Chemical Ligation. Journal of Organic Chemistry, 71 (18), 6846-6850. doi: 10.1021/jo060960p

Amon, Michael A., Ali, Marina, Bender, Vera, Chan, Yiu-Ngok, Toth, Istvan and Manolios, Nicholas (2006). Lipidation and glycosylation of a T cell antigen receptor (TCR) transmembrane hvdrophobic peptide dramatically enhances in vitro and in vivo function. Biochimica Et Biophysica Acta-molecular Cell Research, 1763 (8), 879-888. doi: 10.1016/j.bbamcr.2006.04.013

Olive, Colleen, Sun, Hsien Kuo, Ho, Mei‐Fong, Dyer, Joanne, Horvath, Aniko, Toth, Istvan and Good, Michael F. (2006). Intranasal administration is an effective mucosal vaccine delivery route for self-adjuvanting lipid core peptides targeting the group A streptococcal M protein. Journal of Infectious Diseases, 194 (3), 316-324. doi: 10.1086/505580

Olive, Colleen, Ho, Mei‐Fong, Dyer, Joanne, Lincoln, Douglas, Barozzi, Nadia, Toth, Istvan and Good, Michael F. (2006). Immunization with a tetraepitopic lipid core peptide vaccine construct induces broadly protective immune responses against group A streptococcus. Journal of Infectious Diseases, 193 (12), 1666-1676. doi: 10.1086/504266

Toth, Istvan, Moyle, Peter, Karpati, Levente, Horvath, Aniko, Olive, Colleen and Good, Michael (2006). The lipid core peptide system in vaccine delivery. International Congress Series, 1289, 307-310. doi: 10.1016/j.ics.2005.11.057

Hayes, Patricia Y., Ross, Benjamin P., Thomas, Bradley G. and Toth, Istvan (2006). Polycationic lipophilic-core dendrons as penetration enhancers for the oral administration of low molecular weight heparin. Bioorganic & Medicinal Chemistry, 14 (1), 143-152. doi: 10.1016/j.bmc.2005.08.004

Moyle, P. M., Olive, C., Ho, M. F., Good, M. F. and Toth, I. (2006). Synthesis of a highly pure lipid core peptide based self-adjuvanting triepitopic group A Streptococcal vaccine, and subsequent immunological evaluation. Journal of Medicinal Chemistry, 49 (21), 6364-6370. doi: 10.1021/jm060475m

Everett, Ruth S., Vanhook, Miriam K., Barozzi, Nadia, Toth, Istvan and Johnson, Larry G. (2006). Specific modulation of airway epithelial tight junctions by apical application of an occludin peptide. Molecular Pharmacology, 69 (2), 492-500. doi: 10.1124/mol.105.017251

Liang, M T, Davies, N M, Blanchfield, J T and Toth, I (2006). Particulate systems as adjuvants and carriers for peptide and protein antigens. Current Drug Delivery, 3 (4), 379-388. doi: 10.2174/156720106778559029

Bornaghi, L., Dekany, G., Drinnan, N. B., Taylor, S., Toth, I. and West, M. L. (2006). Dde as a protecting group for carbohydrate synthesis. Journal of Carbohydrate Chemistry, 25 (1), 1-18. doi: 10.1080/07328300500388685

Wimmer, N., Robinson, J. A., Gopisetty Venkata, N., Roberts-Thomson, S. J., Monteith, G. R. and Toth, I. (2006). Anti-proliferative effects of novel Glyco-lipid-arsenicals (III) on MCF-7 human breast cancer cells. Medicinal Chemistry, 2 (1), 79-87. doi: 10.2174/157340606775197714

Moyle, P. M., Olive, C., Ho, M.-F., Burgess, M., Karpati, L., Good, M. F. and Toth, I. (2006). Towards the synthesis of a highly pure, multiepitopic, mucosal group A streptoccal lipopeptide vaccine. International Congress Series, 1289, 324-328. doi: 10.1016/j.ics.2005.11.084

Moyle, P. M., Olive, C., Good, M. F. and Toth, I. (2006). Method for the synthesis of highly pure vaccines using the lipid core peptide system. Journal of Peptide Science, 12 (12), 800-807. doi: 10.1002/psc.815

White, Karen, Rades, Thomas, Kearns, Philip, Toth, Istvan and Hook, Sarah (2006). Immunogenicity of liposomes containing lipid core peptides and the adjuvant Quil A. Pharmaceutical Research, 23 (7), 1473-1481. doi: 10.1007/s11095-006-0272-z

Pignatello, Rosario, Guccione, Salvatore, Castelli, Francesco, Sarpietro, Maria G., Giurato, Laura, Lombardo, Massimo, Puglisi, Giovanni and Toth, Istvan (2006). Enhancement of drug affinity for cell membranes by conjugation with lipoamino acids II. Experimental and computational evidence using biomembrane models. International Journal of Pharmaceutics, 310 (1-2), 53-63. doi: 10.1016/j.ijpharm.2005.11.044

Caccetta, R., Blanchfield, J. T., Harrison, J., Toth, I. and Benson, H. A. E. (2006). Epidermal penetration of a therapeutic peptide by lipid conjugation; Stereo-selective peptide availability of a topical diastereomeric lipopeptide. International Journal of Peptide Research and Therapeutics, 12 (3), 327-333. doi: 10.1007/s10989-006-9024-5

Wu, S., Christopher, C., Koda, Y., Blanchfield, J. T. and Toth, I. (2006). Investigation of the route of absorption of lipid and sugar modified leu-enkephalin analogues and their enzymatic stability using the Caco-2 cell monolayer system. Medicinal Chemistry, 2 (2), 203-211. doi: 10.2174/157340606776056205

Parekh, H. S., Marano, R. J., Rakoczy, E. P., Blanchfield, J. and Toth, I. (2006). Synthesis of a library of polycationic lipid core dendrimers and their evaluation in the delivery of an oligonucleotide with hVEGF inhibition. Bioorganic & Medicinal Chemistry, 14 (14), 4775-4780. doi: 10.1016/j.bmc.2006.03.029

Bayele, Henry K., Ramaswamy, Chandrasekaran, Wilderspin, Andrew F., Srai, Kaila S., Toth, Istvan and Florence, Alexander T. (2006). Protein transduction by lipidic peptide dendrimers. Journal of Pharmaceutical Sciences, 95 (6), 1227-1237. doi: 10.1002/jps.20606

Marano, R. J., Toth, I., Wimmer, N., Brankov, M. and Rakoczy, E. P. (2005). Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: A long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity. Gene Therapy, 12 (21), 1544-1550. doi: 10.1038/sj.gt.3302579

Ross, B. P. and Toth, I. (2005). Gastrointestinal absorption of Heparin by lipidization or coadministration with penetration enhancers. Current Drug Delivery, 2 (3), 277-287. doi: 10.2174/1567201054367968

Dulhunty, Angela F., Cengia, Louise, Young, Jacqui, Pace, Suzy M., Harvey, Peta J., Lamb, Graham D., Chan, Yiu-Ngok, Wimmer, Norbert, Toth, Istvan and Casarotto, Marco G. (2005). Functional implications of modifying RyR‐activating peptides for membrane permeability. British Journal of Pharmacology, 144 (6), 743-754. doi: 10.1038/sj.bjp.0705981

Johnstone, K. D., Dieckelmann, M., Jennings, M. P., Toth, I. and Blanchfield, J. T. (2005). Chemo-enzymatic synthesis of a trisaccharide-linked peptide aimed at improved drug-delivery. Current Drug Delivery, 2 (3), 215-222. doi: 10.2174/1567201054367977

Bayele, Henry, Sakthivel, T., O'Donell, Martin, Pasi, K. John, Wilderspin, Andrew F., Lee, Christine A., Toth, Istvan and Florence, Alexander T. (2005). Versatile peptide dendrimers for nucleic acid delivery. Journal of Pharmaceutical Sciences, 94 (2), 446-457. doi: 10.1002/jps.20230

Blanchfield, J. T., Lew, R. A., Smith, A. I. and Toth, I. (2005). The stability of lipidic analogues of GnRH in plasma and kidney preparations: the stereoselective release of the parent peptide. Bioorganic & Medicinal Chemistry Letters, 15 (6), 1609-1612. doi: 10.1016/j.bmcl.2005.01.069

Liang, M. T., Davies, N. M. and Toth, I. (2005). Encapsulation of lipopeptides within liposomes: Effect of number of lipid chains, chain length and method of liposome preparation. International Journal of Pharmaceutics, 301 (1-2), 247-254. doi: 10.1016/j.ijpharm.2005.06.010

White, K., Kearns, P., Toth, I. and Hook, S. (2004). Increased adjuvant activity of minimal CD8 T cell peptides incorporated into lipid-core-peptides. Immunology And Cell Biology, 82 (5), 517-522. doi: 10.1111/j.1440-1711.2004.01269.x

Marano, Robert J., Wimmer, Norbert, Kearns, Philip S., Thomas, Bradley G., Toth, Istvan, Brankov, Meliha and Rakoczy, P. Elizabeth (2004). Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotide. Experimental Eye Research, 79 (4), 525-535. doi: 10.1016/j.exer.2004.06.023

Ross, Benjamin P., Braddy, April C., McGeary, Ross P., Blanchfield, Joanne T., Prokai, Laszlo and Toth, Istvan (2004). Micellar aggregation and membrane partitioning of bile salts, fatty acids, sodium dodecyl sulfate, and sugar-conjugated fatty acids: correlation with hemolytic potency and implications for drug delivery. Molecular Pharmaceutics, 1 (3), 233-245. doi: 10.1021/mp049964d

Matthias, A., Blanchfield, J. T., Penman, K. G., Toth, I., Lang, C. S., De Voss, J. J. and Lehmann, R. P. (2004). Permeability studies of alkylamides and caffeic acid conjugates from echinacea using a Caco-2 cell monolayer model. Journal of Clinical Pharmacy And Therapeutics, 29 (1), 7-13. doi: 10.1046/j.1365-2710.2003.00530.x

Russell, F. D., Kearns, P., Toth, I. and Molenaar, P. (2004). Urotensin-II-converting enzyme activity of furin and trypsin in human cells in vitro. Journal of Pharmacology And Experimental Therapeutics, 310 (1), 209-214. doi: 10.1124/jpet.104.065425

Olive, C., Batzloff, M., Horvath, A., Clair, T., Yarwood, P., Toth, I. and Good, M. F. (2004). Group A streptococcal vaccine delivery by immunization with a self-adjuvanting M protein-based lipid core peptide construct. Indian Journal of Medical Research, 119 (Suppl.), 88-94.

Horvath, Anikó, Olive, Colleen, Karpati, Levente, Sun, H. K., Good, Hsien K. and Toth, Istvan (2004). Toward the development of a synthetic group A streptococcal vaccine of high purity and broad protective coverage. Journal of Medicinal Chemistry, 47 (16), 4100-4104. doi: 10.1021/jm040041w

Blanchfield, J. and Toth, I. (2004). Lipid, sugar and liposaccharide based delivery systems 2. Current Medicinal Chemistry, 11 (17), 2375-2382. doi: 10.2174/0929867043364621

Moyle, P.M., McGeary, R. P., Blanchfield, J. T. and Toth, I. (2004). Mucosal immunization: Adjuvants and delivery systems. Current Drug Delivery, 1 (4), 385-396. doi: 10.2174/1567201043334588

Olive, C., Batzloff, M.R. and Toth, I. (2004). Lipid core peptide technology and group A streptococcal vaccine delivery. Expert Review of Vaccines, 3 (1), 43-58. doi: 10.1586/14760584.3.1.43

McGeary, R. P., Rasoul Amini, S., Tang, V. W. S. and Toth, I. (2004). Nucleophilic substitution reactions of pyranose polytosylates. Journal of Organic Chemistry, 69 (8), 2727-2730. doi: 10.1021/jo035779k

Ross, B. P., DeCruz, S. E., Lynch, T. B., Davis-Goff, K. and Toth, I. (2004). Design, Synthesis, and Evaluation of a Liposaccharide Drug Delivery Agent: Application to the Gastrointestinal Absorption of Gentamicin. Journal of Medicinal Chemistry, 47 (5), 1251-1258. doi: 10.1021/jm030474j

Moyle, P. M., Horvath, A., Olive, C., Good, M. F. and Toth, I. (2003). Development of lipid-core-peptide (LCP) based vaccines for the prevention of the group A streptococcal (GAS) infection. Letters In Peptide Science, 10 (5-6), 605-613. doi: 10.1007/BF02442594

Benson, Heather A. E., Caccetta, Rima, Chen, Yan, Kearns, Philip and Toth, Istvan (2003). Transdermal delivery of a tetrapeptide: Evaluation of passive diffusion. Letters in Peptide Science, 10 (5-6), 615-620. doi: 10.1007/BF02442595

Olive, Colleen, Batzloff, Michael, Horvath, Aniko, Clair, Timothy, Yarwood, Penny, Toth, Istvan and Good, Michael F. (2003). Potential of lipid core peptide technology as a novel self-adjuvanting vaccine delivery system for multiple different synthetic peptide immunogens. Infection And Immunity, 71 (5), 2373-2383. doi: 10.1128/IAI.71.5.2373-2383.2003

Blanchfield, J. T., Dutton, J. T., Hogg, R. C., Gallagher, O. P., Craik, D. J., Jones, A., Adams, D. J., Lewis, R. J., Alewood, P. F. and Toth, I. (2003). Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of α-conotoxin MII. Journal of Medicinal Chemistry, 46 (7), 1266-1272. doi: 10.1021/jm020426j

Tavelin, S., Hashimoto, K., Malkinson, J., Lazorova, L., Toth, I. and Artursson, P. (2003). A new principle for tight junction modulation based on occludin peptides. Molecular Pharmacology, 64 (6), 1530-1540. doi: 10.1124/mol.64.6.1530

Russell, F. D., Meyers, D. E., Galbraith, A., Bett, N., Toth, I., Kearns, P. S. and Molenaar, P. (2003). Elevated plasma levels of human urotensin-II immunoreactivity in congestive heart failure. American Journal of Physiology - Heart & Circulatory Physiology, 285 (Oct.2003), H1576-H1581. doi: 10.1152/ajpheart.00217.2003

McGeary, R. P., Olive, C. and Toth, I. (2003). Lipid and carbohydrate based adjuvant/carriers in immunology. Journal of Peptide Science, 9 (7), 405-418. doi: 10.1002/psc.467

McGeary, R. P., Szyczew, A. J. and Toth, I. (2003). Biological properties and therapeutic potential of billirubin. Mini Reviews in Medicinal Chemistry, 3 (3), 253-256. doi: 10.2174/1389557033488213

Toth, Istvan (2003). Preface. Mini-Reviews in Medicinal Chemistry, 3 (7), I-I. doi: 10.2174/1389557033487764

Wimmer, Norbert, Marano, Robert J., Kearns, Phillip S., Rakoczy, Elizabeth P. and Toth, Istvan (2002). Syntheses of polycationic dendrimers on lipophilic peptide core for complexation and transport of oligonucleotides. Bioorganic and Medicinal Chemistry Letters, 12 (18), 2635-2637. doi: 10.1016/S0960-894X(02)00511-5

Wong, AK, Ross, BP, Chan, YN, Artursson, P, Lazorova, L, Jones, A and Toth, I (2002). Determination of transport in the Caco-2 cell assay of compounds varying in lipophilicity using LC-MS: enhanced transport of Leu-enkephalin analogues. European Journal of Pharmaceutical Sciences, 16 (3), 113-118. doi: 10.1016/S0928-0987(02)00078-7

Olive, Colleen, Batzloff, Michael R., Horvath, Aniko, Wong, Allan, Clair, Timothy, Yarwood, Penny, Toth, Istvan and Good, Michael F. (2002). A lipid core peptide construct containing a conserved region determinant of the group a streptococcal M protein elicits heterologous opsonic antibodies. Infection And Immunity, 70 (5), 2734-2738. doi: 10.1128/IAI.70.5.2734-2738.2002

Hayman, W. A., Toth, I., Flinn, N., Scanlon, M. and Good, M. F. (2002). Enhancing the immunogenicity and modulating the fine epitope recognition of antisera to a helical group A streptococcal peptide vaccine candidate from the M protein using lipid-core peptide technology. Immunology And Cell Biology, 80 (2), 178-187. doi: 10.1046/j.1440-1711.2002.01067.x

Horvath, Aniko, Olive, Colleen, Wong, Allan, Clair, Timothy, Yarwood, Penny, Good, Michael and Toth, Istvan (2002). Lipoamino acid-based adjuvant carrier system: Enhanced immunogenicity of group a streptococcal peptide epitopes. Journal of Medicinal Chemistry, 45 (6), 1387-1390. doi: 10.1021/jm0110441

Wong, A. and Toth, I. (2001). Lipid, sugar and liposaccharide based delivery systems. Current medicinal chemistry, 8 (9), 1123-36.

Blanchfield, Joanne T., Dutton, Julie T., Hogg, R. C., Craik, D. J., Adams, D. J., Lewis, R. J., Alewood, P. and Toth, I. (2001). The synthesis and structure of an n-terminal dodecanoic acid conjugate of a-conotoxin MII. Letters in Peptide Science, 8 (3-5), 235-239. doi: 10.1023/A:1016577832311

Horvath, Aniko, Olive, Colleen, Wong, Allan, Clair, Timothy, Yarwood, Penny, Good, Michael and Toth, Istvan (2001). A lipophilic adjuvant carrier system for antigenic peptides. Letters in Peptide Science, 8 (3-5), 285-288. doi: 10.1007/BF02446530

McGeary, Ross P., Jablonkai, Istvan and Toth, Istvan (2001). Towards synthetic vaccines built on carbohydrate cores. Letters in Peptide Science, 8 (3-5), 273-276. doi: 10.1007/bf02446528

Drinnan, Nicholas, West, Michael L., Broadhurst, Max, Kellam, Barrie and Toth, Istvan (2001). A novel method for solid-phase synthesis of oligosaccharides using the N-1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl (Dde) linker. Tetrahedron Letters, 42 (6), 1159-1162. doi: 10.1016/S0040-4039(00)02197-3

Wong, A. and Toth, I. (2001). Lipid, sugar and liposaccharide based delivery systems. Current Medicinal Chemistry, 8 (9), 1123-1136.

Pignatello, R., Toth, I. and Puglisi, G. (2001). Structural effects of lipophilic methotrexate conjugates on model phospholipid biomembranes. Thermochimica Acta, 380 (2), 255-264. doi: 10.1016/S0040-6031(01)00679-7

Pignatello, R., Vicari, L., Sorrenti, V., Di Giacomo, C., Spampinato, G., Puglisi, G. and Toth, I. (2001). Lipophilic methotrexate conjugates with glucose-lipoamino acid moieties: Synthesis and in vitro antitumor activity. Drug Development Research, 52 (3), 454-461. doi: 10.1002/ddr.1147

Olive, C., Toth, I. and Jackson, D. (2001). Technological advances in antigen delivery and synthetic peptide vaccine developmental strategies.. Mini Reviews in Medicinal Chemistry, 1 (4), 429-438. doi: 10.2174/1389557013406666

McGeary, R. P., Jablonkai, I. and Toth, I. (2001). Carbohydrate-based templates for synthetic vaccines and drug delivery. Tetrahedron, 57 (41), 8733-8742. doi: 10.1016/S0040-4020(01)00852-3

McGeary, R. P., Wright, K. and Toth, I. (2001). Conversion of glucosamine to galactosamine and allosamine derivatives: Control of inversions of stereochemistry at C-3 and C-4. Journal of Organic Chemistry, 66 (15), 5102-5105. doi: 10.1021/jo010210+

Wong, A. and Toth, I. (2001). Lipid, sugar and liposaccharide based delivery systems. Current Medicinal Chemistry, 8 (9), 1123-1136. doi: 10.2174/0929867013372535

Shah, DS, Sakthivel, T, Toth, I, Florence, AT and Wilderspin, AF (2000). DNA transfection and transfected cell viability using amphipathic asymmetric dendrimers. International Journal of Pharmaceutics, 208 (1-2), 41-48. doi: 10.1016/S0378-5173(00)00534-2

Pignatello, R., Spampinato, G., Sorrenti, V., Di Giacomo, C., Vicari, L., McGuire, J. J. and Toth, I. (2000). Lipophilic methotrexate conjugates with antitumor activity. European Journal of Pharmaceutical Sciences, 10 (3), 237-245. doi: 10.1016/S0928-0987(00)00062-2

Falconer, R. A. and Toth, I. (2000). Synthesis of C-linked sugar-lipoamino acid conjugates. Journal of Peptide Science, 6, 106.

Malkinson, J. P., Falconer, R. A. and Toth, I. (2000). Solid phase synthesis of C-terminal glycopeptides. Journal of Peptide Science, 6, 108.

Wong, A. K., Malkinson, J. P., Keri, G., Artursson, P. and Toth, I. (2000). Liposaccharide based peptide delivery system for tumour selective somatostatin analogues. Journal of Peptide Science, 6 (Supplement 1: 26th European Peptide Society Meeting), 109.

Malkinson, John P., Falconer, Robert A. and Toth, Istvan (2000). Synthesis of C-terminal glycopeptides from resin-bound glycosyl azides via a modified staudinger reaction. Journal of Organic Chemistry, 65 (17), 5249-5252. doi: 10.1021/jo000381z

Florence, A. T., Sakthivel, T. and Toth, I. (2000). Oral uptake and translocation of a polylysine dendrimer with a lipid surface. Journal of Controlled Release, 65 (1-2), 253-259. doi: 10.1016/S0168-3659(99)00237-0

Tóth, Istvan, Oswald, Eric, Mainil, Jacques G., Awad-Masalmeh, Mohamed and Nagy, Béla (2000). Characterization of intestinal cnf1+ Escherichia coli from weaned pigs. International Journal of Medical Microbiology, 290 (6), 539-542. doi: 10.1016/S1438-4221(00)80019-3

Tóth, István, Oswald, Eric, Mainil, Jacques, Awad-Masalmeh, Mohamed and Nagy, Béla (2000). Porcine postweaning diarrhea isolates of Escherichia coli with uropathogenic characters. Advances in Experimental Medicine and Biology, 485, 331-334.

Tóth, István, Oswald, Eric, Szabó, Béla, Barcs, István and Emődy, Levente (2000). Virulence markers of human uropathogenic Escherichia coli strains isolated in Hungary. Advances in Experimental Medicine and Biology, 485, 335-338.

Fletcher, K., Florence, A. T., Gard, P. R., Hillery, A. M., Lloyd, A. W. and Toth, I. (1999). The formation of a paniculate delivery system using MG145-LCP. Journal of Pharmacy and Pharmacology, 51 (SUPPL.).

Toth, I., Sakthivel, T., Wilderspin, A. F., Bayele, H., Lee, C. A. and Florence, A. T. (1999). Novel cationic lipidic peptide dendrimer vectors. In vitro gene delivery. (1).. STP Pharma Sciences, 9 (9), 93-99.

Shah, D. S., Sakthivel, T., Toth, I., Florence, A. T. and Wilderspin, A. F. (1999). Investigation of transfection & cell viability using high concentrations of lipidic dendrimeric lysine.. Journal of Pharm.Pharmacol., 51 (51), 138.

Falconer, R. A., Florence, A. T. and Toth, I. (1999). Lipoamino acid based glycolipids for drug delivery. Journal of Pharm.Pharmacol., 51 (51), 335.

Artursson, P., Keri, G., Malkinson, J. P. and Toth, I. (1999). Lipoamino acid & liposaccharide based peptide delivery system for tumour selective somatostatin analogues. Journal of pharmacy and pharmacology, 51 (51), 299.

Falconer, R. A., Jablonkai, I. and Toth, I. (1999). Efficient synthesis of thioglycosides via a Mitsunobu condensation.. Tetrahedron Letters, 40 (40), 8663-8666. doi: 10.1016/S0040-4039(99)01834-1

Sakthivel, T., Toth , I. and Florence, A. T. (1999). Distribution of a lipidic 2.5 nm diameter dendrimer carrier after oral administration. International Journal of Pharmaceutics, 183 (183), 51-55. doi: 10.1016/S0378-5173(99)00043-5

Toth, I., Malkinson, J. P., Flinn, N. S., Drouillat, B., Artursson, P. M. D. and Keri, G. (1999). Novel lipoamino acid & liposaccharide based system for peptide delivery: application for administering tumour selective somatostatin analogues. Journal of Medicinal Chemistry, 42 (42), 4010-4013. doi: 10.1021/jm9910167

Toth, I., Sakthivel, T., Wilderspin, A. F., Bayele, H., O'Donnell, M., Perry, D. J., Pasi, K. J., Lee, C. A. and Florence, A. T. (1999). Novel cationic lipidic peptide dendrimer vectors in vitro gene delivery. S.T.P. Pharma Sciences, 9 (1), 93-99.

Gadó, I., Ruzsics, Zs, Tóth, I., Király, Margit and Milch, Hedda (1998). Partial inhibition of amplifications by primers of EHEC genes. Acta Microbiologica et Immunologica Hungarica, 45 (2), 239-252.

Kittivoravitkul, Sasitorn, Flinn, Nicholas S., Toth, Istvan and Gregoriadis, Gregory (1998). Preparation and characterization of an IgG-dehydroepiandrosterone conjugate. Journal of Pharmacy and Pharmacology, 50 (SUPPL. 9), 243-243. doi: 10.1111/j.2042-7158.1998.tb02443.x

Lang'at, Caroline C., Watt, Robert A., Toth, Istvan and Phillipson, J. David (1998). Semisynthetic derivatives of quassin. Tetrahedron, 54 (24), 6841-6856. doi: 10.1016/S0040-4020(98)00367-6

Lang'at, Caroline C., Watt, Robert A., Toth, Istvan and Phillipson, J. David (1998). Synthetic bicyclic analogues of quassinoids. Tetrahedron, 54 (24), 6857-6866. doi: 10.1016/S0040-4020(98)00368-8

Sakthivel, T, Toth, I and Florence, AT (1998). Synthesis and physicochemical properties of lipophilic polyamide dendrimers. Pharmaceutical Research, 15 (5), 776-782. doi: 10.1023/A:1011935406664

Pignatello, R, Jansen, G, Kathmann, I, Puglisi, G and Toth, I (1998). Lipoamino acid conjugates of methotrexate with antitumor activity. Journal of Pharmaceutical Sciences, 87 (3), 367-371. doi: 10.1021/js970194p

Kellam, Barrie, Drouillat, Bruno, Dekany, Gyula, Starr, Mike S. and Toth, Istvan (1998). Synthesis and in vitro evaluation of lipoamino acid and carbohydrate-modified enkephalins as potential antinociceptive agents. International Journal of Pharmaceutics, 161 (1), 55-64. doi: 10.1016/S0378-5173(97)00328-1

Drouillat, B, Hillery, AM, Dekany, G, Falconer, R, Wright, K and Toth, I (1998). Novel liposaccharide conjugates for drug and peptide delivery. Journal of Pharmaceutical Sciences, 87 (1), 25-30. doi: 10.1021/js9702123

Wright, K., Falconer, R., Dekany, G., Cocksedge, M. and Toth, I. (1998). Polymeric lipoamino acid based C-glycosides for drug and peptide delivery. Carbohydrate Letters, 3 (3), 187-190.

Drouillat, Bruno, Kellam, Barrie, Dekany, Gyula, Starr, Mike S. and Toth, Istvan (1997). Solid phase synthesis of C-terminal carbohydrate modified enkephalins. Bioorganic and Medicinal Chemistry Letters, 7 (17), 2247-2250. doi: 10.1016/S0960-894X(97)00395-8

Tóth, István, Szécsi, Mihály, Julesz, János and Faredin, Imre (1997). Activity and inhibition of 3-beta-hydroxysteroid dehydrogenase/delta-5-4-lsomerase in human skin. Skin Pharmacology and Physiology, 10 (3), 160-168. doi: 10.1159/000211481

Dekany, Gyula, Wright, Karen and Toth, Istvan (1997). An economical synthesis of Lewis X, sialyl lewis X and their α-galactosyl analogues. Journal of Carbohydrate Chemistry, 16 (7), 983-999. doi: 10.1080/07328309708005732

Dekany, Gyula, Wright, Karen, Ward, Peter and Toth, Istvan (1997). Synthesis of Sialyl Lewis X analogues 2. Journal of Carbohydrate Chemistry, 16 (1), 11-24. doi: 10.1080/07328309708006507

Hillery, A. M., Toth, I. and Florence, A. T. (1996). Biological activity of luteinizing hormone releasing hormone after oral dosing with a novel nanoparticulate delivery system: Co-polymerized peptide particles. Pharmaceutical Sciences, 2 (6), 281-283.

Flinn, Nicholas, Hussain, Ishfaq, Shaw, Andrew, Artursson, Per, Gibbons, William A. and Toth, Istvan (1996). Erratum: 'Oral absorption studies of lipid-polylysine conjugates of thyrotropin releasing hormone (TRH1) and luteinizing hormone releasing hormone (LHRH1)' (Int. J. of Pharaceutics 138 (1996) (167)). International Journal of Pharmaceutics, 143 (1). doi: 10.1016/S0378-5173(96)04762-X

Flinn, Nicholas, Coppard, Steve and Toth, Istvan (1996). Oral absorption studies of lipidic conjugates of thyrotropin releasing hormone (TRH) and luteinizing hormone-releasing hormone (LHRH). International Journal of Pharmaceutics, 137 (1), 33-39. doi: 10.1016/0378-5173(95)04391-8

Hillery, Anya M., Toth, Istvan, Shaw, Andrew J. and Florence, Alexander T. (1996). Co-polymerised peptide particles (CPP) I: Synthesis, characterisation and in vitro studies on a novel oral nanoparticuIate delivery system. Journal of Controlled Release, 41 (3), 271-281. doi: 10.1016/0168-3659(96)01342-9

Hillery, Anya M., Toth, Istvan and Florence, Alexander T. (1996). Co-polymerised peptide particles II: Oral uptake of a novel co-polymeric nanoparticulate delivery system for peptides. Journal of Controlled Release, 42 (1), 65-73. doi: 10.1016/0168-3659(96)01368-5

Flinn, Nicholas, Hussain, Ishfaq, Shaw, Andrew, Artursson, Per, Gibbons, William A. and Toth, Istvan (1996). Oral absorption studies of lipid-polylysine conjugates of thyrotropin releasing hormone (TRH) and luteinizing hormone releasing hormone (LHRH). International Journal of Pharmaceutics, 138 (2), 167-174. doi: 10.1016/0378-5173(96)04538-3

Dekany, Gyula, Wright, Karen, Ward, Peter and Toth, Istvan (1996). Synthesis of sialyl Lewis X analogues. Journal of Carbohydrate Chemistry, 15 (4), 383-398. doi: 10.1080/07328309608005661

Toth, Istvan, Christodoulou, Marika, Bankowsky, Krzysztof, Flinn, Nick, Gibbons, William A, Godeau, Gastou, Moczar, Elemer and Hornebeck, William (1995). Design of potent lipophilic-peptide inhibitors of human neutrophil elastase: In vitro and in vivo studies. International Journal of Pharmaceutics, 125 (1), 117-122. doi: 10.1016/0378-5173(95)00127-5

Zloh, M, Anderson, G, Clarklewis, I, Thomas, R, Benedetti, E, Toth, I and Gibbons, WA (1994). Nmr-Studies of the Cytoplasmic C-Terminal Beta-Subunit Domain of the High-Affinity Ige Receptor. Biochemical Society Transactions, 22 (4), 1027-1029.

Zloh, M, Anderson, G, Clarklewis, I, Nicolau, A, Thomas, R, Toth, I and Gibbons, WA (1994). Spectroscopic and Conformational Studies of the C-Terminal Cytoplasmic Beta-Subunit 46-Peptide of the High-Affinity Ige Receptor. Biochemical Society Transactions, 22 (4), S450-S450.

Flinn, N, Danton, M, Hillery, AM, Wood, IP, Gibbons, WA and Toth, I (1994). A Lipidic Alpha-Amino-Acid Based Synthetic Adjuvant Peptide Complex for Increasing Immunogenicity of Vaccines. Biochemical Society Transactions, 22 (4), 1055-1058.

France, LL, Piatti, PG, Newman, Jfe, Toth, I, Gibbons, WA and Brown, F (1994). Circular dichroism, molecular modeling, and serology indicate that the structural basis of antigenic variation in foot-and-mouth disease virus is α-helix formation. Proceedings of the National Academy of Sciences of the United States of America, 91 (18), 8442-8446. doi: 10.1073/pnas.91.18.8442

Toth, I, Hughes, RA, Dekany, G, Hillery, AM and Ward, P (1994). Synthesis and Oral Uptake Studies of Lipidic and Glyco-Lipidic Conjugates of Beta-Lactam Antibiotics. Liebigs Annalen der Chemie, 1994 (7), 685-688. doi: 10.1002/jlac.199419940709

Toth, I, Flinn, N, Hillery, A, Gibbons, WA and Artursson, P (1994). Lipidic conjugates of luteinizing hormone releasing hormone (LHRH)+ and thyrotropin releasing hormone (TRH)+ that release and protect the native hormones in homogenates of human intestinal epithelial (Caco-2) cells. International Journal of Pharmaceutics, 105 (3), 241-247. doi: 10.1016/0378-5173(94)90108-2

Toth, I, Thompson, G and Ward, P (1994). Lipophilic peptide inhibitors of ribonucleotide reductase enzyme of herpes simplex virus. International Journal of Pharmaceutics, 106 (1), 85-88. doi: 10.1016/0378-5173(94)90279-8

Toth, I, Hillery, AM, Wood, IP, Magnusson, C and Artursson, P (1994). Oral absorption of lipidic amino acid conjugates. International Journal of Pharmaceutics, 102 (1-3), 223-230. doi: 10.1016/0378-5173(94)90059-0

Toth, I (1994). A Novel Chemical Approach to Drug-Delivery - Lipidic Amino-Acid Conjugates. Journal of Drug Targeting, 2 (3), 217-239. doi: 10.3109/10611869408996805

Korakas, D, Valko, K, Wood, I, Gibbons, W and Toth, I (1994). Structure-retention relationships of diastereomeric mixtures of lipidic amino acid conjugates on reversed-phase stationary phases. Journal of Chromatography a, 659 (2), 307-315. doi: 10.1016/0021-9673(94)85072-0

Nagy, Z, Rajnavolgyi, E, Hollosi, M, Toth, GK, Varadi, G, Penke, B, Toth, I, Horvath, A, Gergely, J and Kurucz, I (1994). The Intersubunit Region of the Influenza Virus Haemagglutinin is Recognized by Antibodies During Infection. Scandinavian Journal of Immunology, 40 (3), 281-291. doi: 10.1111/j.1365-3083.1994.tb03464.x

Faredin, I., Toth, I., Wolfing, J., Schneider Gy., Gy and Mesko, E. (1994). In vitro inhibitory effects of 16-methyl-substituted steroids on 5α-reductase in rat and human prostates. Acta Pharmaceutica Hungarica, 64 (5), 171-174.

Anderson, G. J., Biekofsky, R. R., Zloh, M., Toth, G. K., Toth, I., Benedetti, E. and Gibbons, W. A. (1994). Spectroscopy and modelling of the cytoplasmic domain of the gamma-subunit of the high affinity immunoglobulin E receptor. Biomedical peptides, proteins & nucleic acids : structure, synthesis & biological activity, 1 (1), 31-38.

Zhong, Guanming, Toth, Istvan, Reid, Ronald and Brunham, Robert C. (1993). Immunogenicity Evaluation of a Lipidic Amino Acid-Based Synthetic Peptide Vaccine for Chlamydia-Trachomatis. Journal of Immunology, 151 (7), 3728-3736.

Toth, I, Danton, M, Flinn, N and Gibbons, WA (1993). A combined adjuvant and carrier system for enhancing synthetic peptides immunogenicity utilising lipidic amino acids. Tetrahedron Letters, 34 (24), 3925-3928. doi: 10.1016/S0040-4039(00)79265-3

Gao, B, Anderson, GJ, Brammer, MJ, James, CH, Danton, M, Toth, G, Toth, I and Gibbons, WA (1993). Sequence-Specific Antipeptide Antibodies That Recognize Different Subunits of the High-Affinity Ige Receptor. Biochemical Society Transactions, 21 (2), 302-304.

Allen, D, Toth, I, Wright, CW, Kirby, GC, Warhurst, DC and Phillipson, JD (1993). Invitro Antimalarial and Cytotoxic Activities of Semisynthetic Derivatives of Brusatol. European Journal of Medicinal Chemistry, 28 (3), 265-269. doi: 10.1016/0223-5234(93)90143-3

Thomas, RC, Anderson, GJ, Ashton, D, Drake, AF, Toth, I and Gibbons, WA (1992). Synthetic and Conformational Studies of the Alpha-Subunit Cytoplasmic Domain of the Immunoglobulin-E Receptor. Biochemical Society Transactions, 20 (4), 840-841. doi: 10.1042/bst0200840

Wood, IP, Toth, I, Holley, JL and Gibbons, WA (1992). Lipidic peptides. XIII: Synthesis, structure elucidation and in vitro toxicity assessment of chlorambucil conjugates with lipidic acids, lipidic amino acids and their oligomers. International Journal of Pharmaceutics, 87 (1-3), 141-147. doi: 10.1016/0378-5173(92)90237-V

Kokotos, G., Constantinoukokotou, V., Fernandez, E.D., Toth, I. and Gibbons, W.A. (1992). Lipidic Peptides .14. Conversion of Racemic Lipidic Amino-Acids Into Sphingosine and Ceramide Analogs and 1,2-Diamines. Liebigs Annalen der Chemie, 1992 (9), 961-964. doi: 10.1002/jlac.1992199201158

Hughes, RA, Toth, I, Ward, P, McColm, AM, Cox, DM, Anderson, GJ and Gibbons, WA (1992). Lipidic Peptides .5. Penicillin and Cephalosporin Acid Conjugates with Increased Lipophilic Character. Journal of Pharmaceutical Sciences, 81 (8), 845-848. doi: 10.1002/jps.2600810826

Anderson, GJ, Haris, PI, Chapman, D, Romer, JT, Toth, GK, Toth, I and Gibbons, WA (1992). Synthesis and Spectroscopy of Membrane-Receptor Proteins - the Gamma Subunit of the Ige Receptor. European Journal of Biochemistry, 207 (1), 51-54. doi: 10.1111/j.1432-1033.1992.tb17018.x

TOTH, , FERNANDEZ, ED, HAFEEZ, RA, HOLLEY, JL, WOOD, IP, WARD, P and GIBBONS, WA (1992). LIPIDIC PEPTIDES .12. CELLULAR UPTAKE STUDIES OF A LIPIDIC AMINO-ACID, ITS OLIGOMERS AND HIGHLY LIPOPHILIC DRUG CONJUGATES ON EHRLICH ASCITES TUMOR-CELLS. International Journal of Pharmaceutics, 83 (1-3), 131-138. doi: 10.1016/0378-5173(82)90015-1

Delolmo, E, Toth, I, Fonteh, AN and Gibbons, WA (1992). Lipid methyl transferase inhibitory activity of novel α-amino alkylic acid derivatives. International Journal of Pharmaceutics, 81 (2-3), 267-269. doi: 10.1016/0378-5173(92)90019-X

Toth, I, Griffith, IP, Fernandez, ED, Hafeez, RA, Holley, JL, Ward, P and Gibbons, WA (1992). Lipidic peptides. VIII. Cellular uptake studies of lipidic amino acid, its oligomers and highly lipophilic drug conjugates. International Journal of Pharmaceutics, 79 (1-3), 39-45. doi: 10.1016/0378-5173(92)90091-F

Hussain, Rohanah, Toth, Istvan and Gibbons, William A. (1992). Lipidic Peptides, IX. Synthesis, resolution and structural elucidation of lipidic amino acids and their homo‐ and hetero‐oligomers. Liebigs Annalen der Chemie, 1992 (2), 169-171. doi: 10.1002/jlac.199219920131

Toth, I, Anderson, GJ, Hussain, R, Wood, IP, Fernandez, ED, Ward, P and Gibbons, WA (1992). Lipidic peptides X. Synthesis, structural and physico-chemical elucidation of lipidic amino acid conjugates with hydrophilic compounds. Tetrahedron, 48 (5), 923-930. doi: 10.1016/S0040-4020(01)88194-1

Hussain, Rohanah, Toth, Istvan and Gibbons, William A. (1992). Lipidic Peptides, IX. Synthesis and Structural Elucidation of Lipophilic Azidothymidine Conjugates. Liebigs Annalen der Chemie, 1992 (2), 169-171. doi: 10.1002/jlac.199219920131

Hughes, RA, Toth, I, Ward, P, Ireland, SJ and Gibbons, WA (1991). Lipidic Peptides .3. Lipidic Amino-Acid and Oligomer Conjugates of Morphine. Journal of Pharmaceutical Sciences, 80 (12), 1103-1105. doi: 10.1002/jps.2600801202

TOTH, , HUGHES, RA, WARD, P, MCCOLM, AM, COX, DM, ANDERSON, GJ and GIBBONS, WA (1991). FATTY PEPTIDES .6. PENICILLIN AND CEPHALOSPORIN ESTERS WITH INCREASED LIPOPHILIC CHARACTER. International Journal of Pharmaceutics, 77 (1), 13-20.

Hussain, Rohanah, Toth, Istvan and Gibbons, William A. (1991). Lipidic Peptides .7. Synthesis and Structure Elucidation of Gamma-Aminobutyric-Acid Conjugates with Lipidic Acids, Lipidic Amino-Acids and Lipidic Peptides. Liebigs Annalen der Chemie, 1991 (9), 963-966. doi: 10.1002/jlac.1991199101165

Toth, I, Hughes, RA, Ward, P, Baldwin, MA, Welham, KJ, McColm, AM, Cox, DM and Gibbons, WA (1991). Lipidic peptides. IV. Penicillin and cephalosporin amide conjugates with lipidic amino acids and their oligomers. International Journal of Pharmaceutics, 73 (3), 259-266. doi: 10.1016/0378-5173(91)90418-N

Toth, I, Hughes, RA, Munday, MR, Murphy, CA, Mascagni, P and Gibbons, WA (1991). Lipidic peptides. II. Synthesis, activity and transport of anti-inflammatory benzoquinolizine-lipidic peptide conjugates. International Journal of Pharmaceutics, 68 (1-3), 191-198. doi: 10.1016/0378-5173(91)90141-A

Kahan Zs., Zs, Toth, I. and Vecsernyes, M. (1991). Low dose aminoglutethimide therapy without glycocorticoid administration. Clinical and hormonal findings. Magyar Onkologia, 35 (1), 7-12.

Gibbons, William A., Hughes, Richard A., Charalambous, Mario, Christodoulou, Marika, Szeto, Alice, Aulabaugh, Anne E., Mascagni, Paolo and Toth, Istvan (1990). Lipidic peptides, I. Synthesis, resolution and structural elucidation of lipidic amino acids and their homo‐ and hetero‐oligomers. Liebigs Annalen der Chemie, 1990 (12), 1175-1183. doi: 10.1002/jlac.1990199001215

SENALDI, E, LEE, MH, TOTH, and GRACE, W (1990). HODGKINS-DISEASE AFTER NON-HODGKINS MALIGNANT-LYMPHOMA IN ACQUIRED-IMMUNE-DEFICIENCY-SYNDROME. Cancer, 66 (5), 960-964. doi: 10.1002/1097-0142(19900901)66:5<960::AID-CNCR2820660525>3.0.CO;2-3

Toth, I., Cohen, M. L., Rumschlag, H. S., Riley, L. W., White, E. H., Carr, J. H., Bond, W. W. and Wachsmuth, I. K. (1990). Influence of the 60-megadalton plasmid on adherence of Escherichia coli 0157:H7 and genetic derivatives. Infection and Immunity, 58 (5), 1223-1231. doi: 10.1128/IAI.58.5.1223-1231.1990

Baldwin, MA, Welham, KJ, Toth, I and Gibbons, WA (1988). Hydride abstraction in fast atom bombardment. Organic Mass Spectrometry, 23 (10), 697-699. doi: 10.1002/oms.1210231004

Vizi, E. Sylvester, Toth, Istvan, Somogyi, George T., Szabo, Lajos, Harsing, Laszlo G. and Szantay, Csaba (1987). Berbanes: A New Class of Selective α2-adrenoceptor Antagonists. Journal of Medicinal Chemistry, 30 (8), 1355-1359. doi: 10.1021/jm00391a015

Tóth, István, Bozsár, Gabriella, Szabó, Lajos, Baitz‐Gács, Eszter, Tamás, József and Szántay, Csaba (1987). Investigations on the Chemistry of Berbanes, XII. Synthesis of Pseudo‐Depyrroloyohimbine Analogues. Liebigs Annalen der Chemie, 1987 (3), 243-247. doi: 10.1002/jlac.198719870315

Tóth, István, Bozsár, Gabriella, Szabó, Lajos, Tamás, József, Baitz‐Gács, Eszter and Szántay, Csaba (1987). Investigations on the Chemistry of Berbanes, XIII. Selective Reduction of Normal‐, Allo‐, Pseudo‐, and Epiallo‐Depyrrolo‐Yohimbone Analogues. Liebigs Annalen der Chemie, 1987 (12), 1021-1024. doi: 10.1002/jlac.198719870867

Toth, I, Szabo, L, Bozsar, G, Szantay, C, Szekeres, L and Papp, JG (1984). Investigations On the Chemistry of Berbanes .10. Synthesis of Raunescinone Analogs with Hypotensive and Antihypertensive Activity. Journal of Medicinal Chemistry, 27 (11), 1411-1415. doi: 10.1021/jm00377a006

TOTH, and TOTH, M (1983). EFFECT OF THIOCARBAMATE HERBICIDES ON THE MEMBRANE-STRUCTURE AND TRANSPORT PROCESSES OF THE RICE ROOT. Botanikai Kozlemenyek-Botanical Publications, 70 (3-4), 139-149.

Valko, K, Toth, I, Ward, P, Slegel, P and Gibbons, WA (1982). Lipidic peptides. XI. Quantitative structure-activity relationships of a series of lipidic amino acid conjugates of β-lactam antibiotics. International Journal of Pharmaceutics, 83 (1-3), 123-130. doi: 10.1016/0378-5173(82)90014-X

Toth, I, Szabo, L, Tamas, J and Szantay, C (1979). Investigation On the Chemistry of Berbans .8. Synthesis of Inside Depyrrolo-Yohimbine Analogs. Tetrahedron, 35 (17), 2043-2047. doi: 10.1016/S0040-4020(01)88976-6

Szabo, L, Nogradi, K, Toth, I, Szantay, C, Radics, L, Virag, S and Kanyo, E (1979). Synthesis of Benzo[A]Quinolizidine Derivatives Showing Anti-Inflammatory Activity Without Ulcerogen Side-Effect. Acta Chimica Academiae Scientarium Hungaricae, 100 (1-4), 19-36.

Apsimon, JW and Toth, I (1979). Approaches to triterpene synthesis. Methyl group migration during catalytic hydrogenation of some precursors. Journal of the Chemical Society-Chemical Communications (2), 67-67. doi: 10.1039/C39790000067

Szabo, L., Nogradi, K. and Toth, I. (1979). Synthesis of benzo[a]quinolizidine derivatives showing antiinflammatory activity without ulcerogen side effect. Acta Chimica Academiae Scientiarum Hungaricae, 100 (1-4), 19-36.

Toth, I, Szabo, L, Kajtarperedi, M, Baitzgacs, E, Radics, L and Szantay, C (1978). Investigation On Chemistry of Berbans .7. Synthesis of 10,11-Dimethoxy(Depyrrolo)Raunescine Stereoisomers. Tetrahedron, 34 (14), 2113-2122. doi: 10.1016/0040-4020(78)89011-5

Szabo, L, Toth, I, Toke, L and Szantay, C (1977). Investigations On Chemistry of Berbans .5. Synthesis of 18-Acyloxy-10,11-Dimethoxy-(Depyrrolo)Alloyohimbinones. Justus Liebigs Annalen der Chemie (4), 634-641.

Szabo, L, Toth, I, Toke, L, Szantay, C and Tamas, J (1977). Investigations On Chemistry of Berbans .6. New Synthesis of 10-Methoxy(Depyrrolo)-Reserpine and its Stereoisomers. Justus Liebigs Annalen der Chemie (4), 642-663.

Szabó, Lajos, Tóth, István, Tőke, László and Szántay, Csaba (1977). Untersuchungen über Verbindungen mit Berban‐Gerüst, V. Über die Synthese von 18‐Acyloxy‐10,11‐dimethoxy(despyrrolo)‐alloyohimbinone. Justus Liebigs Annalen der Chemie, 1977 (4), 634-641. doi: 10.1002/jlac.197719770414

Szabó, Lajos, Tóth, István, Tőke, László, Szántay, Csaba and Tamás, József (1977). Untersuchungen über Verbindungen mit Berban‐Gerüst, VI. Neue Synthese von 10‐Methoxy(despyrrolo)reserpin und seinen Stereoisomeren. Justus Liebigs Annalen der Chemie, 1977 (4), 642-663. doi: 10.1002/jlac.197719770415

Szabo, L, Toth, I, Toke, L, Kolonits, P and Szantay, C (1976). Investigation On Chemistry of Berbans .4. Synthesis of Halogen Containing Depyrroloyohimbon Derivatives with Pg-Like and Pg-Antagonistic Effect. Chemische Berichte-Recueil, 109 (10), 3390-3403. doi: 10.1002/cber.19761091017

Szabo, L, Toth, I, Honty, K, Toke, L, Tamas, J and Szantay, C (1976). Investigation On Chemistry of Berbans .3. Regiospecific Synthesis of Depyrroloyohimbinone by Dieckmann Condensation of Unsaturated Esters. Chemische Berichte-Recueil, 109 (5), 1724-1736. doi: 10.1002/cber.19761090516

Szabó, Lajos, Honty, Katalin, Töke, László, Tóth, István and Szántay, Csaba (1972). Untersuchungen über Verbindungen mit Berban‐Gerüst, I Synthese von Dimethoxy‐despyrrolo‐yohimbin und Dimethoxy‐despyrrolo‐β‐yohimbin. Chemische Berichte, 105 (10), 3215-3230. doi: 10.1002/cber.19721051010

Szabó, Lajos, Honty, Katalin, Töke, László, Tóth, István and Szántay, Csaba (1972). Untersuchungen über Verbindungen mit Berban‐Gerüst, II Aufbau des allo‐Berban und epi‐allo‐Berban‐Gerüsts. Chemische Berichte, 105 (10), 3231-3243. doi: 10.1002/cber.19721051011

Madge, Harrison, Alexander, Suzy, Azuar, Armira, Zhang, Jiahui, Koirala, Prashamsa, Burne, Thomas, Toth, Istvan and Stephenson, Rachel (2024). Synthetic anti-cocaine nano-vaccine successfully prevents cocaine-induced hyperlocomotion. 37th European Peptide Symposium 14th International Peptide Symposium, Florence, Italy, 25-29 August 2024. Oxford, United Kingdom: John Wiley & Sons.

Tóth, István and Skwarczynski, Mariusz (2021). Lipopeptide nanoparticulate vaccine candidates for the induction of protective immune responses. DDRS 2021 Conference, Budapest, Hungary, 15-17 November 2021. Budapest, Hungary: Hungarian Pharmaceutical Association. doi: 10.33892/aph.2021.91.124-125

Nevagi, Reshma Jayprakash, Dai, Wei, Khalil, Zeinab, Hussein, Waleed, Capon, Robert, Skwarczynski, Mariusz and Toth, Istvan (2019). Development of polymer-based nanoparticulate intranasal lipopeptide vaccine constructs against group A streptococcus. National Meeting of the American Chemical Society (ACS), Orlando, FL, United States, 31 March - 4 April, 2019. Washington, DC, United States: American Chemical Society.

Aljohani, Salwa, Hussein, Waleed M., Toth, Istvan and Simerska, Pavla (2019). Carbohydrates in vaccine development. Controlled Release Asia Meeting, Singapore, 24-25 September, 2018. Sharjah, United Arab Emirates: Bentham Science Publishers. doi: 10.2174/1567201816666190702153612

Moradi, S. V., Varamini, P. and Toth, I. (2014). Glycosylation of Luteinizing Hormone Releasing Hormone: Towards the Development of Orally Active Peptides. HOBOKEN: WILEY.

Skwarczynski, Mariusz, Liu, Tzu-Yu, Hussein, Waleed M., Jia, Zhongfan, Ziora, Zyta M., McMillan, Nigel A. J., Monteiro, Michael J. and Toth, Istvan (2014). Synthesis of therapeutic vaccine against cervical cancer. 4th Asia-Pacific International Peptide Symposium in conjunction with 50th Japanese Peptide Symposium, Osaka, Japan, 6-8 November 2013. Osaka, Japan: Japanese Peptide Society.

Moradi, S. V., Varamini, P. and Toth, I. (2014). Glycosylation of luteninzing hormone releasing hormoe: towards the development of orally active peptide. Dr. Bert L. Schram Young Investigators' Mini-Symposium. 33EPS 2014: 33rd European Peptide Symposium, Sofia, Bulgaria, 31 August-5 September, 2014. Chichester, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.2686

Rupenthal, I., Chen, Y. S., Teague, R., Perrett, J., Danesh-Meyer, H., Toth, I. and Green, C. (2013). Modified connexin43 mimetic peptide shows higher efficacy in reducing retinal ganglion cell loss and vessel leak after retinal ischemia. European Association for Vision and Eye Research Annual Meeting 2013, Nice, France, 18-21 September 2013. Malden, MA, United States: Wiley-Blackwell. doi: 10.1111/j.1755-3768.2013.1744.x

Skwarczynski, M., Fuaad, A. A. H. A., Zaman, M., Jia, Z., Kowapradit, J., Rustanti, L., Ziora, Z. M., Monteiro, M. L. J., Batzloff, M. R., Goodc, M. F. and Toth, I. (2012). Nanoparticles-based peptide subunit vaccines against group A Streptococcus. 32nd European Peptide Symposium, Athens, Greece, 2-7 September 2012. Chichester, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.2448

Toth, Istvan, Simerska, Pavla and Skwarczynsky, Mariusz (2011). Dendritic delivery systems for peptide vaccines. 1st European Conference of Microbiology and Immunology, Budapest, Hungary, 12-14 May 2011. Budapest, Hungary: Akademiai Kiado. doi: 10.1556/EuJMI.1.2011.2.1

Coles, Daniel J., Simerska, Pavla, Fujita, Yoshio and Toth, Istvan (2011). The influence of incorporating lipids or liposaccharides on the particle size of peptide therapeutics. 8th Australian Peptide Conference. Peptides: Tools, Targets and Therapeutics, Coran Cove, South Stradbroke Island, QLD, Australia, 11-16 October 2009. Hoboken, NJ, U.S.A.: John Wiley & Sons. doi: 10.1002/bip.21459

Zaman, Mehfuz, Abdel-Aal, Abu-Baker, Fujita, Yoshio, Batzloff, Michael, Good, Michael and Toth, Istvan (2011). Development of 3-component Mucosal Group A streptococcus (GAS) Vaccine Candidate. 22nd American Peptide Symposium, San Diego Ca, Jun 25-30, 2011. MALDEN: WILEY-BLACKWELL.

Toth, Istvan, Moyle, Peter M., Simerska, Pavla, Fujita, Yoshio, Olive, Colleen and Good, Michael F. (2009). Vaccine delivery: Synthesis and investigation of a highly pure, multi-epitopic lipopeptide vaccine candidate. 20th American Peptide Symposium, Montréal, Quebec, Canada, 26-30 June 2007. New York: Springer. doi: 10.1007/978-0-387-73657-0_154

Simerska, Pavla, McGeary, Ross P., Abdel-Aal, Abu-Baker M., Moyle, Peter M., Olive, Colleen, Good, Michael F. and Toth, Istvan (2009). Vaccine delivery utilizing liposaccharides. The 20th American Peptide Symposium, Montreal, Canada, 26-30 June, 2007. United States: Springer. doi: 10.1007/978-0-387-73657-0_153

Toth, Istvan, Simerska, Pavla and Fujita, Yoshio (2008). Recent advances in design and synthesis of self-adjuvanting lipopeptide vaccines. doi: 10.1007/s10989-008-9147-y

Bergeon, Julie A., Chan, Yiu-Ngok, Charles, Bruce G. and Toth, Istvan (2008). Oral absorption enhancement of dipeptide L-Glu-L-Trp-OH by lipid and glycosyl conjugation. doi: 10.1002/bip.21003

Coles, Daniel J., Yang, Shu, Minchin, Rodney F. and Toth, Istvan (2008). The characterization of a novel dendritic system for gene delivery by isothermal titration calorimetry. New York, N.Y.: John Wiley & Sons Ltd. doi: 10.1002/bip.21019

Bulmer, A.C., Coombes, J.S., Blanchfield, J.T., Toth, I. and Taylor, S.M. (2008). Absorption and pharmacokinetics of bilirubin and biliverdin administration in the rat. Australian Health and Medical Research Congress, Brisbane, 16 - 21 November, 2008.

Bulmer, A. C., Blanchfield, J. T., Toth, I., Fassett, R. G. and Coombes, J. S. (2008). Improved resistance to serum oxidation in Gilberts syndrome: a mechanism for cardiovascular protection. The 2008 meeting of the Society for Free Radical Research - Europe (SFRR-E, Berlin, Germany, 5th-9th July 2008. London: Gordon and Breach. doi: 10.1080/10715760802207914

Simerska, Pavla, Abdel-Aal, Abu-Baker M., Fujita, Yoshio, Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2008). Synthesis and in vivo studies of carbohydrate-based vaccines against group A Streptococcus. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/bip.20992

Bulmer, A. C., Coombes, J. S., Blanchfield, J. T., Toth, I., Fassett, R. G. and Taylor, S. M. (2008). Intestinal and intraperitoneal absorption and bioavailability of the antioxidants unconjugated bilirubin, biliverdin and bilirubin ditaurate in the rat. SFRR-E Berlin, Berlin, Germany, 5-9 July, 2008. London: Gordon and Breach. doi: 10.1080/10715760802207914

Fujita, Yoshio, Moyle, Peter M., Hieu, Suzanne, Simerska, Pavla and Toth, Istvan (2008). Investigation toward multi-epitope vaccine candidates using native chemical ligation. Hoboken, NJ, U.S.A.: John Wiley & Sons. doi: 10.1002/bip.21002

Toth, I., Moyle, P. M., Simerska, P., Fujita, Y., Olive, C. and Good, M. F. (2007). Vaccine delivery: Synthesis and investigation of a highly pure, multi-epitopic lipopeptide vaccine candidate. 20th American Peptide Symposium, Montréal, Quebec, Canada, 26-30 June 2007. HOBOKEN: Wiley Periodicals. doi: 10.1002/bip.20783

Simerska, P., Moyle, P. M., Zhong, W., McGeary, R., Abdel-Aal, A. B., Good, M. F. and Toth, I. (2007). Vaccine Delivery Utilizing Liposaccharides. 20th American Peptide Symposium, Montréal, Quebec, Canada, 26-30 June 2007. Hoboken: John Wiley & Sons. doi: 10.1002/bip.20783

Simerska, P., Abdel-Aal, A. B., McGeary, R., Moyle, P.M., Fujita, Y., Good, M.F. and Toth, I. (2007). Peptide-lipid-carbohydrate based vaccine against group A Streptococcal infection.. 13th International Congress of Immunology, Rio de Janeiro, Brazil, August 21-25.

Toth, I., Moyle, P. M., Simerska, P., Fujita, Y., Olive, C. and Good, M. F. (2007). Novel lipoamino acid based vaccine adjuvant carrier system. International Congress of Immunology, Rio de Janeiro, Brazil, 21-25 August 2007. Toronto, Canada: Hogrefe & Huber.

Abdel-Aal, A. M., Batzloff, M. R., Faria, A., Fujita, Y., Good, M. F., Phillipps, K. S. M., Simerska, P., Toth, I. and Zaman, M. (2007). The importance of epitope and lipid orientation in the design of synthetic self-adjuvanting group A streptococcal (GAS) vaccine. 4th international Peptide Symposium in conjunction with the 7th Australian Peptide Conference and the 2nd Asia-Pacific International Peptide Symposium, 2007, Cairns, Queensland, Australia, 21 - 25 October 2007. Australian Peptide Association.

Fujita, Y., Moyle, P., Abdel-Aal, A., Batzloff, M., Good, M. and Toth, I. (2007). Development of a Multivalent Heteroepitopic Group A Streptococcus Vaccine. 4th International Peptide Symposium, Cairns, 21-25 October 2007. Australia: Australian Peptide Association.

Simerska, P., Moyle, P. M., Abdel-Aal, A. M., Fujita, Y., Olive, C., Batzloff, M. R., Good, M. F. and Toth, I. (2007). Liposaccharides in Peptide Vaccine Delivery. 4th International Peptide Symposium, Cairns, 21-25 October 2007. Australia: Australian Peptide Association.

Coles, D., Yang, S., Esposito, A., Mitchell, D., Minchin, R. and Toth, I. (2007). The Characterisation of Novel Dendritic Carriers with DNA by Isothermal Titration Calorimetry. 4th International Peptide Symposium, Cairns, 21-25 October 2007. Australia: Australian Peptide Association.

Bergeon, J., Chan, Y. and Toth, I. (2007). Enhancement of Oral Drug Absorption - Effect of Lipid and Glycoside Conjugation on the Enzymatic Stability and Intestinal Permeability of IM862. 4th International Peptide Symposium, Cairns QLD Australia, 21-25 October 2007. Australia: Australian Peptide Association.

Caccetta, Rima, Blanchfield, Joanne T., Harrison, Jessica, Toth, Istvan and Benson, Heather A. E. (2006). Epidermal penetration of a therapeutic peptide by lipid conjugation; stereo-selective peptide availability of a topical diastereomeric lipopeptide. doi: 10.1007/s10989-006-9024-5

Moyle, Peter M., Horvath, Aniko, Karpati, Levente, Olive, Colleen, Barozzi, Nadia, Wimmer, Norbert, Good, Michael and Toth, Istvan (2006). Development of peptide vaccines against HPV-16 associated cervical cancer and group a streptococci. 19th American Peptide Symposium, San Diego, United States, 18-23 June 2005. New York, United States: Springer. doi: 10.1007/978-0-387-26575-9_169

Liang, M, Hennessy, T., Toth, I, Davies, N M and Hook, S. (2006). Synthetic lipopeptides formulated in liposomes: Effect on their immune stimulatory capacity in vitro. 2006 International Conference on Nanoscience and Nanotechnoloy, Brisbane / Brisbane Convention Centre, 3-7 July 2006. Canberra: IEEE.

Abdel-Aal, A. M. and Toth, I (2006). Structure-activity relationships of potential self-adjuvanting vaccines against Group A streptococcus based on the carboxyl group of its M-protein. Brisbane Biological & Organic Chemistry Symposium, Brisbane, 24 November 2006.

Bergeon, J and Toth, I (2006). Enhancement of drug oral absorption - effect of lipidic conjugation on the stability and permeability of a dipeptide amide derivative in Caco-2 models. Brisbane Biological & Organic Chemistry Symposium, Brisbane, 24 November 2006.

Coles, D. J., Yang, S, Esposito, A., Mitchell, D J, Minchin, R F and Toth, I (2006). The synthesis of a novel dendritic system for gene delivery. Brisbane Biological & Organic Chemistry Symposium, Brisbane, 24 November 2006.

Del Borgo, M, Wang, R., Toth, I and Blanchfield, J T (2006). Synthesis and characterisation of Trp modified Leu-Enkephalin analogues. Brisbane Biological & Organic Chemistry Symposium, Brisbane, 24 Nov 2006.

Khoshnejad, M., Toth, I., Young, P. R. and Minchin, R. F. (2006). Modified influenza virosomes for gene delivery. Brisbane Biological & Organic Chemistry Symposium, Brisbane, Qld, 24 Nov 2006.

Moyle, P. M., Olive, C., Ho, M.-F., Good, M F and Toth, I (2006). Highly pure, multi-epitopic lipopeptide vaccine delivery system: Synthesis and investigation. Brisbane Biological & Organic Chemistry Symposium, Brisbane, 24 Nov 2006.

Simerska, P, Moyle, P. M., Olive, C., Sun, H., Ho, M.-F., Pandy, M.G., Dyer, J. R., Burgess, M L and Toth, I (2006). Development of vaccines for the prevention and/or treatment of human papillomavirus type-16 associated cervical cancer. Brisbane Biological & Organic Chemistry Symposium, Brisbane, 24 November 2006.

Wessling, S., Ross, B P, Blanchfield, J T and Toth, I (2006). Caco-2 cell permeability and stability assays of two d-glycopyranuronanamide conjugates of thyrotropic releasing hormone. Brisbane Biological & Organic Chemistry Symposium, Brisbane, 24 Nov 2006.

Simerska, P., Bong, Y. K., McGeary, R. P., Moyle, P. M. and Toth, I. (2006). Liposaccharide based vaccine carrier adjuvant systems. Drug Design Amongst the Vines, Hunter Valley, 3 - 7 December 2006.

Toth, I., Moyle, P. M., Simerska, P., Fujita, Y., Olive, C. and Good, M. F. (2006). Liposaccharides in peptide, gene and vaccine delivery. Drug Design Amongst the Vines, Hunter Valley, 3 - 7 December, 2006.

Abdel-Aal, A. M., Fujita, Y., Faria, A., Simerska, P., Batzloff, M. R., Good, M. F. and Toth, I. (2006). Development of totally synthetic self-adjuvanting vaccines against Group A streptococcus. Annual Conference of the Australasian Pharmaceutical Science n, Adelaide, Australia, 3-5 December 2006. Malvern, VIC: Australasian Pharmaceutical Science Association.

Yang, S, Coles, D. J., Esposito, A., Mitchell, D J, Toth, I and Minchin, R F (2006). Uptake of a multi-component non-viral gene delivery system and gene expression in mammalian cells. Annual Conference of the Australasian Pharmaceutical Science n, Adelaide, 3-5 December, 2006.

Del Borgo, M, Koda, Y., Blanchfield, J T, Toth, I and Okada, Y. (2006). Drug development of endomorphin-1. 29th European Peptide Symposium, Gdansk, 3-8 Sept, 2006. CHICHESTER: JOHN WILEY & SONS LTD.

Toth, I, Moyle, P. M., Koda, Y., Olive, C. and Good, M F (2006). Liposaccharides in peptide, gene and vaccine delivery. 10th Naples Workshop on Bioactive Peptides, Naples, 11-14 June, 2006.

Coles, D. J., Yang, S., Esposito, A., Mitchell, D. J., Minchin, R. F. and Toth, I. (2006). The synthesis of a novel dendritic system for gene delivery. Annual Conference of the Australasian Pharmaceutical Science Association, Adelaide, Australia, 3-5 December, 2006.

Liang, M, Monteiro, M J and Toth, I (2006). Chemoselective peptide attachment to well-defined star polymer for peptide delivery. Annual Conference of the Australasian Pharmaceutical Science n, Adelaide, 3-5 Dec, 2006.

Toth, I., Moyle, P. M., Koda, Y., Olive, C. and Good, M. F. (2006). Liposaccharides in peptide, gene and vaccine delivery. 33rd Annual Meeting and Exposition of the Controlled Release Soy, Vienna, 22-26 July, 2006.

Moyle, P. M., Olive, C., Ho, M.-F. and Toth, I (2006). Highly pure, multi-epitopic lipopeptide vaccine delivery system: Synthesis and investigation. GPEN 2006, Lawrence, USA, 25 - 27 Oct, 2006.

Simerska, P., Moyle, P. M., Olive, C., Sun, H. K., Ho, M. F., Pandy, M. G., Dyer, J. R., Burgess, M. L. and Toth, I. (2006). Development of vaccines for the prevention and/or treatment of human papillomavirus type-16 associated cervical cancer. GPEN 2006, Lawrence, USA, 25-27 October, 2006.

Wimmer, N, Robinson, JA, Gopisetty-Venkatta, N, Roberts-Thomson, SJ, Monteith, GR and Toth, I (2006). Novel glyco-lipid-arsenicals(III) with anti-proliferative effects on MCF-7 human breast cancer cells. 19th American Peptide Symposium, San Diego, CA, United States, June 18-23 2005. New York, N.Y., United States: Springer. doi: 10.1007/978-0-387-26575-9_148

Toth, I., Moyle, P. M., Karpati, L., Horvath, A., Olive, C. and Good, M. F. (2006). The lipid core peptide system in vaccine delivery. XVIth Lancefield International Symposium on Streptococci and Streptococcal Diseases, Palm Cove, Australia, 25 and 29 September 2005. Amsterdam, The Netherlands: Excerpta Medica Foundation. doi: 10.1016/j.ics.2005.11.057

Moyle, Peter Michael, Olive, Colleen, Karpati, Levente, Barozzi, Nadia, Ho, Mei-Fong, Dyer, Joanne, Sun, Hsien Kuo, Good, Michael and Toth, Istvan (2006). Synthesis and immunological evaluation of M protein targeted tetra-valent and tri-valent group A streptococcal vaccine candidates based on the lipid-core peptide system. 6th Australian Peptide Conference, Whitsunday Islands, Australia, 9-14 October, 2005. Netherlands: Springer. doi: 10.1007/s10989-006-9021-8

Fujita, Y, Moyle, P. M., Olive, C., Good, M F and Toth, I (2006). Multi-epitopic lipid core peptide vaccine with broad protective immune responses against Group A streptococcus. 29th European Peptide Symposium, Gdansk, 3-8 Sept, 2006.

Fujita, Y., Moyle, P., Olive, C., Good, M. and Toth, I. (2006). Multi-epitopic lipid core peptide vaccine with broad protective immune responses against Group A Streptococcus. CHICHESTER: JOHN WILEY & SONS LTD.

Liang, Ming T., Hennessy, Tania, Toth, Istvan, Davies, Nigel M. and Hook, Sarah (2006). Synthetic lipopeptides formulated in liposomes: effect on their immune stimulatory capacity in vitro. International Conference on Nanoscience and Nanotechnology, Brisbane Australia, Jul 03-07, 2006. NEW YORK: IEEE.

Johnstone, Ken D., Dieckelmann, Manuela, Jennings, Michael P., Blanchfield, Joanne T. and Toth, Istvan (2006). The chemo-enzymatic synthesis of oligosaccharide-linked peptides aimed at improved drug delivery. 19th American Peptide Symposium, San Diego, CA, United States, 18-23 June 2005. New York, NY, United States: Springer. doi: 10.1007/978-0-387-26575-9_221

Liang, Ming T., Hennessy, Tania, Toth, Istvan, Davies, Nigel M. and Hook, Sarah (2006). Synthetic lipopeptides formulated in liposomes: effect on their immune stimulatory capacity in vitro. International Conference on Nanoscience and Nanotechnology, Brisbane, QLD, Australia, 3-7 July 2006. Piscataway, NJ, United States: IEEE. doi: 10.1109/ICONN.2006.340608

Olive, C., Hsien, K., Horvath, A., Clair, T., Yarwood, P., Toth, I. and Good, M. F. (2005). Protection against group A streptococcal infection by vaccination with self-adjuvanting lipid core M protein peptides. 4th World Congress on Vaccines and Immunisation (WCVI), Tokyo Japan, Sep 30-Oct 03, 2004. Oxford, U.K.: Elsevier. doi: 10.1016/j.vaccine.2005.01.041

Moyle, Peter M., Olive, Colleen, Sun, Hsien, Good, Michael and Toth, Istvan (2005). The synthesis and immunological activity of a lipid-core peptide (LCP) based Human Papillomavirus (HPV) type-16 vaccine. 3rd International Peptide Symposium and 28th European Peptide Symposium, Prague, Czech Republic, 5-10 September 2004. GENEVA 1: Kenes International.

Wimmer, N., Robinson, J. A., Thomson, S. J., Monteith, G. R. and Toth, I. (2005). Anti-proliferative effects of novel glyco-lipoaminoacid-modified arsenicals (III) on MCF-7 human breast cancer cells. 19th American Peptide Symposium, San Diego, U.S., 18-23 June, 2005. Hoboken, U.S.: Wiley Interscience.

Horvath, Aniko, Olive, Colleen, Good, Michael F. and Toth, Istvan (2005). A synthetic group A streptococcal vaccine of high purity and broad protective range. 3rd International Peptide Symposium/28th European Peptide Symposium, Prague Czech Republic, Sep 05-10, 2004. GENEVA 1: KENES INT.

Johnstone, K.D., Dieckelmann, M., Jennings, M.P., Blanchfield, J.T. and Toth, I. (2005). The chemoenzymatic synthesis of oligosaccharide-linked peptides aimed at improved drug delivery. 19th American Peptide Symposium, San Diego, CA, United States, 18-23 June 2005. Hoboken, NJ, United States: John Wiley & Sons .

Toth, I., Horvath, A., Karpati, L., Moyle, P., Olive, C. and Good, M. (2004). Liposaccharides for drug and vaccine delivery. 3rd International and 28th European Peptide Symposium, Prague, Czech Republic, 5–10 September 2004. Chichester, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.618

Liang, M.T., Davies, N. M. and Toth, I. (2004). Incorporation of lipoamino acids - peptide conjugates within liposomes: Effect of alkyl chain length, number of alkyl chains and method of liposome preparation. Annual Conference of the APSA, 2004, Melbourne, Vic, Australia, 4-7 December, 2004. Mount Waverley, Victoria: Australasian Pharmaceutical Science Association.

Blanchfield, J. T., Gallagher, O. P., Koda, Y., Alewood, P.F., Lewis, R. J. and Toth, I. (2004). Liposaccharides in peptide drug delivery. 18th American Peptide Symposium, Boston, 19-23 July, 2003. WASHINGTON: AMER CHEMICAL SOC.

Toth, I., Horvath, A., Blanchfield, J. T., Olive, C., Good, M. F., Wimmer, N. and Rakoczy, E.P. (2004). Lipid and carbohydrate based macromolecules in drug and vaccine delivery. 18th American Peptide Symposium, Boston, 19-23 July, 2004.

Toth, I. (2004). Novel vaccine delivery systems. GPEN 2004, Kyoto, 26-28 May, 2004.

Blanchfield, J. T., Koda, Y., Gallagher, O. P. and Toth, I. (2004). Liposaccharide delivery system: application to conotoxin MII and endomorphin I. PSWC 2004, Kyoto, 29 May - 3 June, 2004.

Koda, Y., Blanchfield, J. T., Okada, Y. and Toth, I. (2004). A novel liposaccharide system for the delivery of Endormorphin 1. PSWC 2004, Kyoto, 29 May- 3 June, 2004.

Blanchfield, J. T., Koda, Y., Gallagher, O. P. and Toth, I. (2004). Liposaccharide delivery system: Application to Conotoxin MII and Endomorphin 1. 20th RACI Organic Chemistry Conference, Cairns, 4-8 July, 2004.

Liang, M. T., Davies, N. M. and Toth, I. (2004). Preparation of peptide functionalized nanoparticles by interfacial polymerisation of w/o microemulsions. CTP 2004, Brisbane, 1-6 Aug 2004. Australia: Blackwell Publishing Asia.

Kearns, P., Russell, F. D., Toth, I. and Molenaar, P. (2004). Investigation of urotensin-II converting enzyme activity in human cells and blood. 8th Annual Scientific Sessions of the Latin American Section of the International-Society for Heart Research, Brisbane, Qld, Australia, 7th - 11th August, 2004. United Kingdom: Academic Press. doi: 10.1016/j.yjmcc.2004.05.003

Toth, I., Horvath, A., Olive, C., Good, M. F., Wimmer, N. and Rakoczy, E. P. (2003). Lipid and carbohydrate based macromolecules in drug and vaccine delivery. 26th Australian Polymer Symposium, Noosa, Queensland, 13-17 July 2003. Australia: Royal Australian Chemical Institute.

Toth, I., Horvath, A., Blanchfield, J. T., Olive, C., Good, M. F., Wimmer, N. and Rakoczy, E. P. (2003). Lipid and carbohydrate based macromolecules in drug and vaccine delivery. Brisbane Biological and Organic Chemistry Symposium, Gold Coast, 28 November, 2003.

Blanchfield, J. T., Gallagher, O. P., Koda, Y. and Toth, I. (2003). Liposacchride delivery system: Application to peptides conotoxin MII and endomorphin I. Brisbane Biological and Organic Chemistry Symposium, Gold Coast, 28 Nov, 2003.

Blanchfield, J. T., Chan, Y., Rhee, H., Alewood, P.F., Adams, D. J. and Toth, I. (2003). Liposaccharide delivery system: Application for peptide IT-100, LHRH and conotoxin MII. 18th American Peptide Symposium, Boston, USA, 19-23 July, 2003. HOBOKEN: JOHN WILEY & SONS INC.

Toth, I, Horvath, A, Olive, C and Good, MF (2003). Vaccine design against streptococcal infection. 18th American Peptide Symposium, Boston Ma, Jul 19-23, 2003. HOBOKEN: JOHN WILEY & SONS INC.

Marano, R. J., Wimmer, N., Kearns, P. S., Thomas, B. G., Toth, I., Wilson, A. S., Brankov, M. and Rakoczy, P. E. (2003). Use of synthetic dendrimer peptide's to mediate the delivery of a sense oligonucleotide. Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology, Ft Lauderdale Florida, May, 2003. Rockville, MD United States: Association for Research in Vision and Ophthalmology.

Marano, R. J., Wimmer, N., Kearns, P. S., Thomas, B. G., Toth, I., Wilson, A. S., Brankov, M. and Rakoczy, P. E. (2003). Oligonucleotide gene therapy for choroidal neovascularisation enhanced by dendrimer mediated delivery. 3rd Meeting of the Australasian-Gene-Therapy-Society, Brisbane Australia, Apr 30-May 02, 2003. CHICHESTER: Wiley.

Horvath, A., Olive, C., Good, M. F. and Toth, I. (2002). A novel immunoadjuvant carrier system for synthetic peptides. 27th European Peptide Symposium, Sorrento, Italy, 31 Aug. - 6 Sept. 2002. Napoli, Italy: E. Ziino.

Toth, I., Horvath, A., McGeary, R. P., Hayman, W. A., Olive, C. and Good, M. F. (2002). Lipid-core-peptides for vaccination: Structure-activity relationship. 27th European Peptide Symposium, Sorrento, Italy, 31 Aug. - 6 Sept. 2002. Napoli, Italy: Edizioni Ziino.

Blanchfield, J. T. and Toth, I. (2002). Modify the bioactive to increase the availability and potency of a drug: Lipids and sugars in drug delivery and vaccine development. 8th International Pacific Rim Biotechnology Conference, Auckland, NZ, 17-20 Nov. 2002.

Toth, I., McGeary, R. P. and Tang, V.W.S. (2002). Reactions of carbohydrate tosylates and mesylates with nucleophiles: Control of inversions of stereochemistry. XX1st International Carbohydrate Symposium, Cairns, 7-12 July 2002.

Toth, I., Blanchfield, J. T., McGeary, R. P., Ross, B. P. and Chan, Y. (2002). Liposaccharides in drug delivery. XX1st International Carbohydrate Symposium, Cairns, 7-12 July 2002.

McGeary, Ross P., Jablonkai, Istvan and Toth, Istvan (2001). Towards synthetic vaccines built on carbohydrate cores. Netherlands: Springer. doi: 10.1023/A:1016212726860

Chan, Y., Wong, A. K. and Toth, I. (2001). Caco-2 cell permeability of peptide IT-100 and its conjugates; and investigation of transport mechanisms of sacchride conjugates. APSA Annual Conference 2001, Melbourne, 9-12 Dec 2001. Melbourne: Australasian Pharmaceutical Science Association.

Moyle, P.M., Mcgeary, R. P. and Toth, I. (2001). Solid-phase synthesis of oligosaccharides utilising a novel Dde-based linker. APSA Annual Conference 2001, Melbourne, 9-12 Dec 2001. Melbourne: Australasian Pharmaceutical Science Association.

Toth, I. (2001). Lipoamino acids and liposaccharides: Enhanced peptide delivery. 38th IUPAC World Chemistry Congress 2001, Brisbane, 1-6 July 2001. Brisbane: Royal Australian Chemical Institute.

Mcgeary, R. P., Blanchfield, J. T., Rhee, H., Alewood, P.F. and Toth, I. (2001). Enhancing peptide delivery using lipoamino acids and liposaccharides.. 7th International Symposium on Solid Phase Synthesis & Combinatorial Chemical Libraries, Southampton, UK, 18-22 Sept 2001. UK: European Peptide Society & BS/RSC Protein & Peptide Group, UK.

Toth, I., Mcgeary, R. P., Blanchfield, J. T., Rhee, H., Alewood, P.F. and Good, M. F. (2001). Lipids and sugars: Application for peptide delivery and for enhancing synthetic peptide immunogenicity. 4th Australian Peptide Conference, Lindeman Is., Queensland, 7-12 Oct 2001.

Toth, I., Mcgeary, R. P. and Blanchfield, J. T. (2001). Applications of lipoamino acids and liposaccharides for peptide delivery and enhancing immunogenicity. 2nd International Peptide Symposium, 17th American Peptide Symposium, San Diego, USA, 9-15 June 2001. San Diego, USA: American Peptide Society.

Blanchfield, J. T., Rhee, H. and Toth, I. (2001). The synthesis and biological activity of an orally available liposaccharide analogue of LHRH.. Brisbane Biological & Organic Chemistry Symposium 2001, University of Queensland, Brisbane, 30 Nov 2001. Brisbane:

Rhee, H., Blanchfield, J. T. and Toth, I. (2001). Novel liposaccharide based system for delivering LHRH orally.. APSA Annual Conference 2001, Melbourne, 9-12 Dec 2001. Melbourne: Australasian Pharmaceutical Science Association.

Blanchfield, J. T., Alewood, P.F., Lewis, R. J., Dutton, J. L., Craik, D. J. and Toth, I. (2001). Synthesis of lipo- and liposacchride a-conotoxin MII conjugates. World Chemistry Congress, Brisbane, Australia, 1-6 July, 2001. Royal Australian Chemical Institute.

Mcgeary, R. P., Wright, K. and Toth, I. (2001). Allosamines and galactosamines from glucosamine: Control of stereochemical inversions at C-3 and C-4. 11th European Carbohydrate Symposium, Lisbon, Portugal, 2-7 Sept 2001. Lisbon, Portugal:

Mcgeary, R. P., Wright, K. and Toth, I. (2001). Allosamines and galactosamines from glucosamine: Control of stereochemical inversions at C-3 and C-4.. Brisbane Biological and Organic Chemistry Symposium 2001, UQ, Brisbane, 30 Nov 2001. Brisbane:

Blanchfield, J. T., Dutton, J. L., Craik, D. J., Alewood, P.F., Lewis, R. J., Adams, D. J. and Toth, I. (2001). Synthesis of lipo- and liposaccharide a-conotoxin MII conjugates.. APSA Annual Conference 2001, Melbourne, Australia, 9-12 December, 2001. Melbourne, Australia: Australasian Pharmaceutical Science Association.

Mcgeary, R. P. and Toth, I. (2001). Carbohydrate-based carrier adjuvants in vaccine technology. Peptidomimetics Symposium 2001, Belgium, 9-14 Sept 2001. European Peptide Society.

Blanchfield, J. T., Rhee, H. and Toth, I. (2001). The synthesis and biological activity of an orally available liposaccharide analogue of LHRH.. APSA Annual Conference 2001, Melbourne, 9-12 Dec 2001. Melbourne: Australasian Pharmaceutical Science Association.

Chan, Y., Wong, A. K. and Toth, I. (2001). Lipoamino acid and liposaccharide conjugated peptides: Enhancement of bioavailability.. 2nd International Peptide Symposium & 17th American Peptide Symposium, San Diego, California, 9-14 June 2001. California: American Peptide Society.

Kearns, P. S., Wimmer, N., Rakoczy, P. E. and Toth, I. (2001). Synthesis of cationic lipidic peptide dendrimer vectors for in vitro oligonucleotide delivery.. APSA Annual Conference 2001, Melbourne, 9-12 Dec 2001. Melbourne: Australasian Pharmaceutical Science Association.

Olive, C., Schubert, A., Wong, A. K., Good, M. F. and Toth, I. (2001). Lipid-core-peptides for vaccination: A structure-activity relationship study.. 4th Australian Peptide Conference, Lindeman Island, Qld., 7-12 Oct 2001.

Schubert, A., Olive, C., Wong, A. K., Good, M. F. and Toth, I. (2001). Enhanced immunogenicity of group A streptococcal peptide epitopes by lipoamino acid based adjuvant carrier system.. APSA Annual Conference 2001, Melbourne, 9-12 Dec 2001. Melbourne: Australasian Pharmaceutical Science Association.

Mcgeary, R. P., Schubert, A., Olive, C., Hayman, W., Good, M. F. and Toth, I. (2001). Synthetic vaccines containing multiple copies of group A streptococcus peptide epitopes.. APSA Annual Conference 2001, Melbourne, 9-12 Dec 2001. Melbourne: Australasian Pharmaceutical Science Association.

Mcgeary, R. P., Schubert, A., Olive, C., Hayman, W., Good, M. F. and Toth, I. (2001). Synthetic vaccines: Enhanced immunogenicity of Streptococcus peptide epitopes.. Brisbane Biological & Organic Chemistry Symposium 2001, University of Queensland, Brisbane, 30 Nov 2001.

Falconer, R. A. and Toth, I. (2001). C-linked sugar - lipoamino acid conjugates. 26th European Peptide Conference, Montpellier, France, 10-15 Sept 2000. Paris, France: EDK.

Malkinson, J. P., Lazorova, L., Artursson, P., Keri, G. and Toth, I. (2001). Glycolipid-modified peptides: Enhancement of absorption of an anti-tumour somatostatin analogue. 26th European Peptide Conference, Montpellier, France, 10-15 Sept 2000. Paris, France: EDK.

Wong, A. K., Ross, B. P., Artusson, P., Lazorova, L. and Toth, I. (2001). Determination of the transport across Caco-2 cell monolayers of compounds varying in lipophilicity using LC-MS. 26th European Peptide Conference, Montpellier, France, 10th - 15th September, 2000. Paris, France: EDK.

Jordan, L. R., Kearns, P. S. and Toth, I. (2001). Further characterization of an astrocyte secreted factor that increases transendothelial electrical resistance in an in vitro model of the blood-brain barrier. Int. Congress of Physiological Sciences 2001 Satellite, Tasmania, 21-24 August. International Union of Physiological Sciences (IUPS).

Toth, I., Mcgeary, R. P., Blanchfield, J. T., Rhee, H., Alewood, P. F., Adams, D. J. and Good, M. F. (2001). Liposaccharides: Utilisation for peptide delivery and for enhancing synthetic peptide immunogenicity.. 2nd International & 17th American Peptide Symposium, San Diego, California, US, 9-14 June, 2001. San Diego, CA: American Peptide Society.

Schubert, A., Olive, C., Wong, A. K., Good, M. F. and Toth, I. (2001). Lipid-core-peptides for vaccination.. Brisbane Biological & Organic Chemistry Symposium 2001, Univerity of Queensland, Brisbane, 30 Nov 2001. Brisbane:

Mcgeary, R. P. and Toth, I. (2001). Synthetic vaccines built on carbohydrate cores. 4th Australian Peptide Conference, Lindeman Is., Qld, 7-12 Oct 2001. Australian Peptide Society.

Malkinson, JP, Keri, G, Artursson, P and Toth, I (2000). Novel lipoamino acid and liposaccharide based peptide delivery system for tumor selective somatostatin analogs. 16th American Peptide Symposium, Minneapolis Mn, Jun 26-Jul 01, 1999. DORDRECHT: SPRINGER.

Malkinson, J. P., Keri, G., Artursson, P. and Toth, I. (2000). Novel lipoamino acid and liposaccharide based peptide delivery system for tumour selective somatostatin analogues. 16th American Peptide Symposium, Minnesota, USA, 26th June - 1 July, 1999. Dordrecht: Kluwer Academic.

Chan, Y., Wong, A. K. and Toth, I. (2000). Liposaccharides: Applications for oral peptide delivery. Departmental Seminar, School of Pharmacy, The University of Queensland, Brisbane, 8 November 2000. Brisbane: The University of Queensland.

Chan, Y., Wong, A. K. and Toth, I. (2000). Lipoamino acid and liposaccharide based peptide delivery system. APSA 2000 Annual Conference, Newcastle, NSW, 6-8 December 2000. Brisbane, Australia: University of Qld.

Chan, Y., Wong, A. K. and Toth, I. (2000). Synthesis of lipoamino acid and liposaccharide based peptides for enhancement of oral bioavailability. The First Brisbane Biological and Organic Chemistry Symposium, Griffith University, Brisbane, 27 November 2000. Brisbane, Australia: Griffith Unversity.

Malkinson, J. P., Lazorova, L., Artusson, P., Keri, G. and Toth, I. (2000). Glycolipid-modified peptides: Enhancement of absorption of an anti-tumour somatostatin analogue. 20th International Carbohydrate Symposium, Hamburg, Germany, 27 Aug - 1 Sep 2000. Hamburg, Germany: Carbohydrate Society.

Falconer, R. A. and Toth, I. (2000). Synthesis of C-linked lipoamino acid based glycolipids. 20th International Carbohydrate Symposium, Hamburg, Germany, 27 Aug - 1 Sep 2001. Hamburg: Carbohydrate Society.

Sakthivel, T., Yanai, S., Toth, I. and Florence, A. T. (2000). Synthesis and characterisation of linear amphipathic lysine-lipid conjugates. Millennial World Congress of Pharmaceutical Sciences, San Francisco, USA, 16-20 April 2000. San Francisco, USA: International Pharmaceutical Federation USA.

Falconer, R. A. and Toth, I. (2000). Synthesis of amphipathic glycolipids for drug delivery. Millennial World Congress of Pharmaceutical Sciences, San Francisco, USA, 16-20 April 2000. San Francisco, USA: International Pharmaceutical Federation USA.

Malkinson, J. P., Lazorova, L., Artursson, P., Keri, G. and Toth, I. (2000). Lipoamino acid and glycolipid conjugated peptides enhanced intestinal absorption of an anti-tumour somatostatin analogue. Millennial World Congress of Pharmaceutical Sciences, San Francisco, USA, 16-20 April 2000. San Francisco, USA: International Pharmaceutical Federation USA.

Wong, A. K., Ross, B. P., Jones, A., Artursson, P., Lazorova, L. and Toth, I. (2000). Measurement of the transport across CaCo -2 cell monolayers of compounds varying in lipophilicity using LC-MS. The First Brisbane Biological & Organic Chemistry Symposium, Griffith University, 27 Nov. 2000. Australia: McGraw Hill.

Blanchfield, J. T., Adams, D. J., Alewood, P. F., Lewis, R. J. and Toth, I. (2000). A novel liposaccharide based system for peptide drug delivery. The APSA 2000 Annual Conference, Newcastle, 6th - 8th December, 2000. Australia: APSA.

Wong, A. K., Ross, B. P., Jones, A., Artursson, P., Lazorova, L. and Toth, I. (2000). Determination of the transport across CACO-2 cell monolayers of compounds varying in lipophilicity using LC-MS. APSA 2000 Annual Conference, Newcastle, 6-8 December, 2000. Australia: The University of Queensland.

Adams, D. J., Alewood, P. F., Blanchfield, J. T., Lewis, R. J. and Toth, I. (2000). A novel liposaccharide based system for peptide drug delivery. The First Brisbane Biological and Organic Chemistry Symposium, Griffith University, Brisbane, 27 November. 2000.

Jablonkai, I and Toth, I (2000). Synthesis of glycopeptide modified IgE epitopes. 16th American Peptide Symposium, Minneapolis Mn, Jun 26-Jul 01, 1999. DORDRECHT: SPRINGER.

Tavelin, S., Hashimoto, K., Lazarova, L., Malkinson, J. P., Toth, I. and Artursson, P. (2000). A new approach to absorption enhancement based on the molecular structure of occludin. Millennial World Congress of Pharmaceutical Sciences, San Francisco, USA, 16-20 April 2000. San Francisco, USA: International Pharmaceutical Federation USA.

Jablonkai, I. and Toth, I. (2000). Synthesis of glycopeptide modified IgE epitopes. 16th American Peptide Symposium, Minnesota, USA, 26 June-1 Jul. 2000. Dordrecht: Kluwer Academic.

Falconer, RA and Toth, (2000). Lipoamino acid based glycoconjugates for peptide and drug delivery. 16th American Peptide Symposium, Minneapolis Mn, Jun 26-Jul 01, 1999. DORDRECHT: SPRINGER.

Pignatello, R., Toth, I., Fresta, M. and Puglishi, G. (1999). Amide & ester type conjugates of methotrexate with lipoamino acids: preparation & antitumour activity. Italian Hungarian Polish Joint Meeting on Medicinal Chemistry, Giardini Naxos, Taormina Sicily, 28 Sept - 1 Oct 1999. Catania: Universita degli Studi di Catania.

Toth, I. (1999). Novel liposaccharide conjugates for drug/peptide delivery & enhancing synthetic peptide immunogenicity. Australian Pharmaceutical Sciences Assoc. 1999 Annual Conf., Fremantle, WA, 28 Nov-1 Dec, 1999. Perth, WA: Curtin Uni.of Technology.

Falconer, R. A. and Toth, I. (1999). Synthesis of amphipathic lipoamino acid-based glycoconjugates PA061, 199. 10th European Carbohydrate Symposium, Galway, Ireland, 11-16 July 1999. Galway, Ireland: National Univ. of Ireland, Galway.

Jablonkai, I. and Toth, I. (1999). Synthesis of 2-amino-2-deoxy-glycoamino acids & glycolipids. 10th European Carbohydrate Symposium, Galway, Ireland, 11-16 July 1999. Galway, Ireland:

Malkinson, J. P., Falconer, R. A. and Toth, I. (1999). Solid phase synthesis of C-terminal glycopeptides via a modified Staudinger reaction. 10th European Carbohydrate Symposium, Galway, Ireland, 11-16 July 1999. Galway, Ireland:

Florence, A. T., Sakthivel, T., Carreno-Gomez, B. and Toth, I. (1999). Oral absorption of nanoparticles & dendrimers: facts & promise. 9th International symposium on recent advances in drug delivery, Salt Lake City, USA, 22-25 Feb 1999.

Malkinson, J. P., Keri, G., Artursson, P. and Toth, I. (1999). Novel lipoamino acid & liposaccharide based peptide delivery system for tumour selective somatostatin analogues. 16TH American Peptide Symposium, Minnesota, USA, 27 June - 1 July 1999. Menneapolis, USA: American Peptide Society.

Toth, I., Wright, K., Flinn, N. S., Malkinson, J. P. and Falconer, R. A. (1999). Novel liposaccharide based drug & peptide delivery systems. European Peptide Conference, Budapest, Hungary, 30 Aug-4 Sept, 1998. Budapest: Academiai Kiado.

Florence, A. T., Sakthivel, T. and Toth, I. (1999). Lipid dendrimers: Oral absorption and distribution.

Sakthivel, T., Florence, A. T. and Toth, I. (1998). Biodistribution and stability of a dendrimer carrier.

Hillery, A. M., Drouillat, B. and Toth, I. (1997). Novel liposaccharide colloidal drug carriers.

Hillery, A. M., Toth, I. and Florence, A. T. (1995). A novel nanoparticulate delivery system for the oral absorption of peptides, II: In vivo studies.

Hillery, A. M., Toth, I. and Florence, A. T. (1995). A novel oral nanoparticulate delivery system, I: Development and in vitro studies.

Toomey, C. M., Flinn, N., Van der Walle, C., Toth, I. and Munday, M. R. (1995). Peptide substrates for AMP-activated protein kinase. Portland Press Ltd. doi: 10.1042/bst023141s

Valkusz Zs., Zs, Galfi, M., Molnar, J., Gardi, J., Toth, I., Julesz, J. and Szarvas, F. (1995). The effects of phenothiazine derivatives on the membrane functions of cultured Leydig cells of rats.

Wright, C. W., Toth, I., Phillipson, J. D. and Warhurst, D. C. (1991). Antiamoebic testing of some natural and synthetic compounds structurally related to berberine.

Hussain, R., Toth, I., Bowery, N. G. and Gibbons, A. (1991). Brain uptake of lipophilic γ-aminobutyric acid conjugate.

Cobos, C., Daly, N., Loukas, A., Bansal, P., Toth, I. and Skwarczynski, M. (2022). New peptide comprising specified amino acid sequence useful for treating or preventing inflammatory or autoimmune condition including inflammatory bowel disease, asthma, rheumatoid arthritis and celiac disease. . WO2022120423.

Toth, I., Horvath, A., Good, M. F. and Olive, C. (2002). A multiple antigen lipophilic adjuvant carrier system (MALAC). Australian Provisional PS2233.

Toth, I. and Falconer, R. A. (2002). Charged liposaccarides for drug delivery. UK-0100115.5; WO2002-AUS-20020103.

Toth, I., Dekany, G. and Kellam, B. (2001). Protected aminosugars. 730910.

Toth, I., Dekany, G. and Kellam, B. (2001). Oligosaccharide synthesis. 728149.

Emeritus Professor Istvan Toth

Researcher biography

Research keywords

Location

Staff profile

Areas of research

Emeritus Professor Istvan Toth

Researcher biography

Research keywords

Location

Staff profile

Publications

Book Chapters

Journal Articles

Conference Papers

Patents

Areas of research